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Categories: Biology: Developmental, Space: Structures and Features

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The central question in the ongoing hunt for dark matter is: what is it made of? One possible answer is that dark matter consists of particles known as axions. A team of astrophysicists has now shown that if dark matter consists of axions, it may reveal itself in the form of a subtle additional glow coming from pulsating stars.

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Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics. The genome of a protist has revealed a seemingly unique divergence in the DNA code signalling the end of a gene, suggesting the need for further research to better understand this group of diverse organisms.  

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Scientists have detected the highest energy gamma rays ever from a dead star called a pulsar. The energy of these gamma rays clocked in at 20 tera-electronvolts, or about ten trillion times the energy of visible light. This observation is hard to reconcile with the theory of the production of such pulsed gamma rays, as the international team reports.

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A pair of theoretical physicists are reporting that the same observations inspiring the hunt for a ninth planet might instead be evidence within the solar system of a modified law of gravity originally developed to understand the rotation of galaxies.

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Researchers have developed a new open-source computational method, dubbed Spectra, which improves the analysis of single-cell transcriptomic data. By guiding data analysis in a unique way, Spectra can offer new insights into the complex interplay between cells — like the interactions between cancer cells and immune cells, which are critical to improving immunotherapy treatments.

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Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study.

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Researchers have produced an engineered tissue representing a simplified cerebral cortex by 3D printing human stem cells. When implanted into mouse brain slices, the structures became integrated with the host tissue. The technique may ultimately be developed into tailored repairs to treat brain injuries.

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In the James Webb Space Telescope’s (JWST) first images of the universe’s earliest galaxies, the young galaxies appear too bright, too massive and too mature to have formed so soon after the Big Bang. Using new simulations, a team of astrophysicists now has discovered that these galaxies likely are not so massive after all. Although a galaxy’s brightness is typically determined by its mass, the new findings suggest that less massive galaxies can glow just as brightly from irregular, brilliant bursts of star formation.

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Researchers have found that a genetic change that increases the risk of inflammation, through a process described as ‘explosive’ cell death, is carried by up to 3% of the global population.

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Scientists reveal new plant cell walls can have significantly different mechanical properties compared to surrounding parental cell walls, enabling cells to change their local shape and influence the growth of plant organs.

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Researchers have identified a new enzyme called PUCH, which plays a key role in preventing the spread of parasitic DNA in our genomes. These findings may reveal new insights into how our bodies detect and fight bacteria and viruses to prevent infections.

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In recent years, astronomy has seen itself in a bit of crisis: Although we know that the Universe expands, and although we know approximately how fast, the two primary ways to measure this expansion do not agree. Now astrophysicists suggest a novel method which may help resolve this tension.

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Researchers identified and characterized a new cellular compartment in vertebrate cells that might be a precursor of today's eucaryotic nucleus. The study reveals that mammalian cells recognize, cluster, sort and keep extrachromosomal DNA -- like transfected plasmid DNA and endogenous circular DNAs originating from telomeres of the chromosome -- away from chromosomal DNA. That suggests that there is a cell autonomous genome defense system.

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A new machine-learning approach helps scientists more efficiently identify the optimal intervention to achieve a certain outcome in a complex system, such as genome regulation, requiring far fewer experimental trials than other methods. 

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By genetically testing nearly one thousand embryos, scientists have provided the most detailed analysis of embryo fate following human in vitro fertilization.

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Surprising findings on the development of sea anemones suggest that a predatory lifestyle molded their evolution and had a significant impact on the origin of their nervous system. The researchers were able to show that the young life stages (larvae) of the small sea anemone Aiptasia actively feed on living prey and are not dependent on algae. To capture its prey, the anemone larvae use specialized stinging cells and a simple neuronal network.

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The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin to cause disfiguring disease, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.

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Some substances in medicines, household items and the environment are known to affect prenatal child development. Researchers tested the effects of five drugs (including caffeine and the blood thinner warfarin) on the growth of zebrafish embryos. They found that all five had the same effect, impairing the migration of bone-forming cells which resulted in the onset of facial malformation. Zebrafish embryos grow quickly, are transparent and develop outside of the parent's body, making them ideal for studying early development. A zebrafish-based system could be used to easily screen for potentially harmful substances, reducing animal testing on mammals and supporting parents-to-be when making choices for themselves and their baby.

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Brain circuits for vision develop without any kind of input from the retina in zebrafish.

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A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development.