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Categories: Biology: Developmental, Space: Structures and Features
Published Brilliant galaxies of early universe
(via sciencedaily.com) Scientists have used data from the James Webb Space Telescope (JWST) as part of the Cosmic Evolution Early Release Science (CEERS) Survey to change the way we think about the universe and its distant galaxies. Astronomers authored a paper confirming very bright galaxies in the early universe, while also disproving the identification of what would have been the most distant galaxy ever found.
Published Genome editing: Reducing off-target mutations in DNA
(via sciencedaily.com) Original source Researchers have developed a novel genome editing technique known as NICER, which results in significantly fewer off-target mutations than CRISPR/Cas9 editing. The technique uses a different type of enzyme that makes single-stranded 'nicks' in the DNA. Repair of these nicks is more efficient and accurate than repair of double-strand breaks caused by the current CRISPR/Cas9 editing. This technique represents a novel approach for the treatment of genetic diseases caused by heterozygous mutations.
Published Snaps supersonic outflow of young star
(via sciencedaily.com) Herbig-Haro (HH) objects are luminous regions surrounding newborn stars, formed when stellar winds or jets of gas spewing from these newborn stars form shock waves colliding with nearby gas and dust at high speeds. This image of HH 211 from NASA's James Webb Space Telescope reveals an outflow from a Class 0 protostar, an infantile analog of our Sun when it was no more than a few tens of thousands of years old and with a mass only 8% of the present-day Sun (it will eventually grow into a star like the Sun).
Published Genetically modified bacteria break down plastics in saltwater
(via sciencedaily.com) Original source Researchers have genetically engineered a marine microorganism to break down plastic in salt water. Specifically, the modified organism can break down polyethylene terephthalate (PET), a plastic used in everything from water bottles to clothing that is a significant contributor to microplastic pollution in oceans.
Published Using topology, Researchers advance understanding of how cells organize themselves
(via sciencedaily.com) Original source R esearchers created a machine learning algorithm using computational topology that profiles shapes and spatial patterns in embryos to study how these cells organize themselves into tissue-like architectures. In a new study, they take that system to the next level, opening a path to studying how multiple types of cells assemble themselves.
Published Researchers discover tissue-specific protection against protein aggregation
(via sciencedaily.com) Original source Researchers have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail. By understanding how different tissues tackle protein build up, this research could accelerate the identification of ways to protect tissues that are vulnerable to protein build up, possibly tackling both disease-associated protein aggregates and also age-dependent aggregates that accelerate the functional decline of tissues.
Published Electrons from Earth may be forming water on the Moon
(via sciencedaily.com) Planetary scientists have discovered that high energy electrons in Earth's plasma sheet are contributing to weathering processes on the Moon's surface and, importantly, the electrons may have aided the formation of water on the lunar surface.
Published Lack of maternal care affects development, microbiome and health of wild bees
(via sciencedaily.com) Original source Most wild bees are solitary, but one tiny species of carpenter bees fastidiously cares for and raises their offspring, an act that translates into huge benefits to the developing bee's microbiome, development and health, found researchers. Without maternal care the pathogen load of these developing bees ballooned -- 85 per cent of were fungi, while eight per cent were bacteria -- which can impact their microbiome, a critical component of bee health, as well as their development, immune system and gene expression.
Published From hagfish to membrane: Modeling age-related macular degeneration
(via sciencedaily.com) Original source Researchers have successfully demonstrated that hagfish slime proteins can accurately replicate membranes in the human eye. Scientists were able to properly grow retinal cells on hagfish slime proteins and prove that the protein's behavior changes as the membrane mimics stages of aging and disease.
Published Flu: Interferon-gamma from T follicular helper cells is required to create lung-resident memory B cells
(via sciencedaily.com) Original source During a bout of influenza, B cells interact with other immune cells and then take different paths to defend the body. One path is the B cells that differentiate into lung-resident memory B cells, or lung-BRMs, that are critical for pulmonary immunity. These long-lived, non-circulating lung-BRMs migrate to the lungs from draining lymph nodes and reside there permanently as the first layer of defense that can quickly react to produce antibodies in a future infection.
Published Matter comprises of 31% of the total amount of matter and energy in the universe
(via sciencedaily.com) One of the most interesting and important questions in cosmology is, 'How much matter exists in the universe?' An international team has now succeeded in measuring the total amount of matter for the second time. The team determined that matter makes up 31% of the total amount of matter and energy in the universe, with the remainder consisting of dark energy.
Published 'Dormant' HIV produces RNA and proteins during anti-retroviral therapy
(via sciencedaily.com) Original source HIV anti-retroviral therapy is considered a treatment and not a cure because patients usually carry a reservoir of HIV-infected cells that can re-emerge if treatment stops. These reservoirs have long been thought to be dormant, but two independent groups of researchers report that a subset of these cells spontaneously produce HIV RNA and proteins that may impact patients' HIV-specific immune responses.
Published Discovery of two potential Polar Ring galaxies suggests these stunning rare clusters might be more common than previously believed
(via sciencedaily.com) These new detections suggest polar ring galaxies might be more common than previously believed.
Published Dark matter halos measured around ancient quasars
(via sciencedaily.com) At the center of every galaxy is a supermassive black hole. Beyond a certain size, these become active, emitting huge amounts of radiation, and are then called quasars. It is thought these are activated by the presence of massive dark matter halos (DMH) surrounding the galaxy, directing matter towards the center, feeding the black hole. A team has now surveyed hundreds of ancient quasars and found this behavior is very consistent throughout history. This is surprising, as many large-scale processes show variation throughout the life of the universe, so the mechanism of quasar activation could have implications for the evolution of the entire universe.
Published Auxin signaling pathway controls root hair formation for nitrogen uptake
(via sciencedaily.com) Original source Root hairs represent a low-cost strategy to enhance nutrient uptake because they can significantly increase the nutrient-acquiring surface of plant roots. While primary and lateral roots are stimulated to elongate when plants grow under mild nitrogen deficiency, the existence of such a foraging response for root hairs and its underlying regulatory mechanism remain elusive. Now, researchers have revealed a framework composed of specific molecular players meditating auxin synthesis, transport and signaling that triggers root hair elongation for nitrogen acquisition.
Published The universe caught suppressing cosmic structure growth
(via sciencedaily.com) As the universe evolves, scientists expect large cosmic structures to grow at a certain rate: dense regions such as galaxy clusters would grow denser, while the void of space would grow emptier.
Published Water world? Methane, carbon dioxide in atmosphere of massive exoplanet
(via sciencedaily.com) A new investigation with NASA's James Webb Space Telescope into K2-18 b, an exoplanet 8.6 times as massive as Earth, has revealed the presence of carbon-bearing molecules including methane and carbon dioxide. Webb's discovery adds to recent studies suggesting that K2-18 b could be a Hycean exoplanet, one which has the potential to possess a hydrogen-rich atmosphere and a water ocean-covered surface.
Published New insights into neutrino interactions
(via sciencedaily.com) Original source Elusive fundamental particles called neutrinos are predicted to interact unexpectedly with photons under extreme conditions.
Published Nutrients drive cellular reprogramming in the intestine
(via sciencedaily.com) Original source Researchers have unveiled an intriguing phenomenon of cellular reprogramming in mature adult organs, shedding light on a novel mechanism of adaptive growth. The study, which was conducted on fruit flies (Drosophila), provides further insights into dedifferentiation -- where specialized cells that have specific functions transform into less specialized, undifferentiated cells like stem cells.
Published These worms have rhythm
(via sciencedaily.com) Original source Researchers have developed a new imaging technique to observe active gene expression in real time. They found that four molecules work together to control the timing of each stage of the C. elegans worm's development. This timekeeping process could provide important clues about the natural rhythm of development in humans and other animals.