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Categories: Biology: Developmental, Physics: Optics

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Making a personalized T cell therapy for cancer patients currently takes at least six months. Scientists have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.

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Researchers have discovered a new class of plasma oscillations -- the back-and-forth, wave-like movement of electrons and ions. The research paves the way for improved particle accelerators and commercial fusion energy.

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Electrical engineers have determined the theoretical fundamental limit for how much electromagnetic energy a transparent material with a given thickness can absorb. The finding will help engineers optimize devices designed to block certain frequencies of radiation while allowing others to pass through, for applications such as stealth or wireless communications.

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In examining the mating rituals of roundworms, researchers uncovered a unique approach to reproduction that maximizes genetic fitness.

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Which process is best suited for mass production of perovskite solar cells? While solvent-based manufacturing processes are used in laboratories around the world, vacuum vapor-phase deposition processes are still the standard for the production of thin films for photovoltaics or organic light-emitting diodes. A new study that reveals major differences in the scientific discussion of these production processes.

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After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo, a new study finds. The work also explains how mutations in egg coat proteins can cause female infertility and may eventually lead to new contraceptive methods.

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To combine two low-energy photons into one high-energy photon efficiently, the energy must be able to hop freely, but not too quickly, between randomly oriented molecules of a solid. The discovery provides a much-needed design guideline for developing materials for more efficient PV cells, displays, or even anti-cancer therapies.

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Mechanical engineers have devised a diagnostic platform that uses sound waves to spin an individual drop of water up to 6000 revolutions per minute. These speeds separate tiny biological particles within samples placed in a very light disc sitting on top of the spinning drop. The technique could allow new point-of-care applications ranging from precision bioassays to cancer diagnosis. The technique requires less time and sample volume while inflicting less damage to delicate exosomes.

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A new process for microscale 3D printing creates particles of nearly any shape for applications in medicine, manufacturing, research and more -- at the pace of up to 1 million particles a day.

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Through steady advances in the development of quantum computers and their ever-improving performance, it will be possible in the future to crack our current encryption processes. To address this challenge, researchers are developing encryption methods that will apply physical laws to prevent the interception of messages. To safeguard communications over long distances, the QUICK space mission will deploy satellites.

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An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.

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A new study reports the discovery of an entirely new stable, earth-abundant, high-performance material for solar absorbers -- the central part of a solar cell that turns light into electricity. While identifying new solar materials is typically very time-consuming, the researchers used a unique high-throughput computational screening method to quickly evaluate around 40,000 candidate materials.

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A team achieves successful mass production of metalenses designed for application in the ultraviolet region.

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Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.

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Adding a fourth light to traffic signals -- in addition to red, green and yellow -- would shorten wait times at street corners for pedestrians, as well as improve traffic flow for both autonomous vehicles and human drivers. And the more autonomous vehicles there are in the traffic network, the shorter the wait times for everyone.

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Research in quantum materials is paving the way for groundbreaking discoveries and is poised to drive technological advancements that will redefine the landscapes of industries like mining, energy, transportation, and medtech. A technique called time- and angle-resolved photoemission spectroscopy (TR-ARPES) has emerged as a powerful tool, allowing researchers to explore the equilibrium and dynamical properties of quantum materials via light-matter interaction.

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A team develops an ultrasensitive broadband transparent ultrasound transducer.

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Researchers have identified the protein that enables mammals to sense cold, filling a long-standing knowledge gap in the field of sensory biology.

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Artificial intelligence (AI) is known for its high energy consumption, especially in data-intensive tasks like health monitoring. To address this, researchers have developed a flexible paper-based sensor composed of nanocellulose and zinc oxide (ZnO) nanoparticles that operates like the human eyes and brain. The sensor is energy-efficient, responds to optical input in real-time, and is both flexible and easy to dispose of, making it ideal for health monitoring applications.

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Researchers have developed a photoacoustic imaging watch for high-resolution imaging of blood vessels in the skin. The wearable device could offer a non-invasive way to monitor hemodynamic indicators such as heart rate, blood pressure and oxygen saturation that can indicate how well a person's heart is working.