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Categories: Biology: Developmental, Physics: Acoustics and Ultrasound
Published Uncovering the secrets behind the silent flight of owls



Owls produce negligible noise while flying. While many studies have linked the micro-fringes in owl wings to their silent flight, the exact mechanisms have been unclear. Now, a team of researchers has uncovered the effects of these micro-fringes on the sound and aerodynamic performance of owl wings through computational fluid dynamic simulations. Their findings can inspire biomimetic designs for the development of low-noise fluid machinery.
Published Low-frequency ultrasound can improve oxygen saturation in blood



Scientists have revealed that low-frequency ultrasound influences blood parameters. The findings suggest that ultrasound's effect on haemoglobin can improve oxygen's transfer from the lungs to bodily tissues. The research was undertaken on 300 blood samples collected from 42 pulmonary patients.
Published Towards the quantum of sound



A team of scientists has succeeded in cooling traveling sound waves in wave-guides considerably further than has previously been possible using laser light. This achievement represents a significant move towards the ultimate goal of reaching the quantum ground state of sound in wave-guides. Unwanted noise generated by the acoustic waves at room temperature can be eliminated. This experimental approach both provides a deeper understanding of the transition from classical to quantum phenomena of sound and is relevant to quantum communication systems and future quantum technologies.
Published DNA construction led to unexpected discovery of important cell function



Researchers have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way. The result opens new avenues for understanding how the Notch signalling pathway works and how it is involved in several serious diseases.
Published Study throws our understanding of gene regulation for a loop



To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.
Published Machine learning reveals sources of heterogeneity among cells in our bodies



A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.
Published Pushing the boundaries of ultrasound imaging: Breaking new ground with ultrafast technology



Researchers have achieved a successful contrast agent-free imaging of complex structure of kidney vessels.
Published Surprisingly simple model explains how brain cells organize and connect



A new study by physicists and neuroscientists describes how connectivity among neurons comes about through general principles of networking and self-organization, rather than the biological features of an individual organism.
Published Bioinformatics: Researchers develop a new machine learning approach



To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.
Published 3D in vitro human atherosclerosis model for high-throughput drug screening



A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.
Published Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging



Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.
Published Aging mouse sperm affects MicroRNA, increasing the risk of neurodevelopmental disorders



Much is known about the added complication to pregnancy when it comes to the age of the mother, but recent studies show that the age of the father can also heighten the risk of neurodevelopmental disorders. A team of researchers has explored the impacts of paternal aging on microRNAs, the molecules that play a crucial role in regulating gene expression.
Published Lab-grown retinas explain why people see colors dogs can't



With human retinas grown in a petri dish, researchers discovered how an offshoot of vitamin A generates the specialized cells that enable people to see millions of colors, an ability that dogs, cats, and other mammals do not possess. The findings increase understanding of color blindness, age-related vision loss, and other diseases linked to photoreceptor cells. They also demonstrate how genes instruct the human retina to make specific color-sensing cells, a process scientists thought was controlled by thyroid hormones.
Published Molecularly designing polymer networks to control sound damping



The world is filled with a myriad of sounds and vibrations -- the gentle tones of a piano drifting down the hall, the relaxing purr of a cat laying on your chest, the annoying hum of the office lights. Imagine being able to selectively tune out noises of a certain frequency. Researchers have now synthesized polymer networks with two distinct architectures and crosslink points capable of dynamically exchanging polymer strands to understand how the network connectivity and bond exchange mechanisms govern the overall damping behavior of the network. The incorporation of dynamic bonds into the polymer network demonstrates excellent damping of sound and vibrations at well-defined frequencies.
Published Protein complex discovered to control DNA repair



The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team has now discovered a previously unrecognized control point for these processes. This could lead to a new approach for the development of cancer therapies aimed at inhibiting the repair of damaged cancer cells.
Published Study on lamprey embryos sheds light on the evolutionary origin of vertebrate head



Scientists have investigated lamprey embryos using cutting-edge microscopic techniques to reveal interesting insights about vertebrate head evolution, clarifying an unresolved mystery in basic science.
Published Smart skin bacteria are able to secrete and produce molecules to treat acne



An experimental study has shown that a type of skin bacterium can efficiently be engineered to produce a protein to regulate sebum production. This application could treat acne without compromising the homeostasis of the entire skin microbiome.
Published Stranger than friction: A force initiating life



As the potter works the spinning wheel, the friction between their hands and the soft clay helps them shape it into all kinds of forms and creations. In a fascinating parallel, sea squirt oocytes (immature egg cells) harness friction within various compartments in their interior to undergo developmental changes after conception.
Published Large-scale mapping of pig genes could pave the way for new human medicines



Researchers have carried out complex genetic analyses of hundreds of pigs and humans to identify differences and similarities. This new knowledge can be used to ensure healthier pigs for farmers and can help the pharmaceutical industry breed better laboratory pigs for testing new medicines.
Published Life span increases in mice when specific brain cells are activated



A new study identifies, in mice, a critical communication pathway connecting the brain and the body's fat tissue in a feedback loop that appears central to energy production throughout the body. The research suggests that the gradual deterioration of this feedback loop contributes to the increasing health problems that are typical of natural aging.