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Categories: Biology: Developmental, Physics: Acoustics and Ultrasound

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A research team has discovered that parasites manipulate their hosts using stolen genes that they likely acquired through a phenomenon called horizontal gene transfer.

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New soft, implantable fibers can deliver light to major nerves through the body. They are an experimental tool for scientists to explore the causes and potential treatments for peripheral nerve disorders in animal models.

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Octopuses are fascinating animals -- and serve as important model organisms in neuroscience, cognition research and developmental biology. To gain a deeper understanding of their biology and evolutionary history, validated data on the composition of their genome is needed, which has been lacking until now. Scientists have now been able to close this gap and, in a new study, determined impressive figures: 2.8 billion base pairs -- organized in 30 chromosomes. What sounds so simple is the result of complex, computer-assisted genome analyses and comparisons with the genomes of other cephalopod species.

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A research group has developed a new method for studying how cancer cells function in softer and stiffer tissue environments. This insight challenges the existing paradigm, opening up new possibilities for research in cancer biology and tissue engineering.

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A group of international scientists have mapped the genetic, cellular, and structural makeup of the human brain and the nonhuman primate brain. This understanding of brain structure allows for a deeper knowledge of the cellular basis of brain function and dysfunction, helping pave the way for a new generation of precision therapeutics for people with mental disorders and other disorders of the brain.

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Researchers describe an acoustic meta-surface that uses pingpong balls, with small holes punctured in each, as Helmholtz resonators to create inexpensive but effective low-frequency sound insulation. The coupling between two resonators led to two resonance frequencies, and more resonant frequencies meant the device was able to absorb more sound. At the success of two coupled resonators, the researchers added more, until their device resembled a square sheet of punctured pingpong balls, multiplying the number of resonant frequencies that could be absorbed.

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A team found a way to deliver clear pictures of anyone's internal anatomy, no matter their skin tone.

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Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics. The genome of a protist has revealed a seemingly unique divergence in the DNA code signalling the end of a gene, suggesting the need for further research to better understand this group of diverse organisms.  

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Researchers have developed a new open-source computational method, dubbed Spectra, which improves the analysis of single-cell transcriptomic data. By guiding data analysis in a unique way, Spectra can offer new insights into the complex interplay between cells — like the interactions between cancer cells and immune cells, which are critical to improving immunotherapy treatments.

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Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study.

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Researchers have produced an engineered tissue representing a simplified cerebral cortex by 3D printing human stem cells. When implanted into mouse brain slices, the structures became integrated with the host tissue. The technique may ultimately be developed into tailored repairs to treat brain injuries.

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Researchers have found that a genetic change that increases the risk of inflammation, through a process described as ‘explosive’ cell death, is carried by up to 3% of the global population.

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Scientists reveal new plant cell walls can have significantly different mechanical properties compared to surrounding parental cell walls, enabling cells to change their local shape and influence the growth of plant organs.

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Researchers have identified a new enzyme called PUCH, which plays a key role in preventing the spread of parasitic DNA in our genomes. These findings may reveal new insights into how our bodies detect and fight bacteria and viruses to prevent infections.

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Researchers identified and characterized a new cellular compartment in vertebrate cells that might be a precursor of today's eucaryotic nucleus. The study reveals that mammalian cells recognize, cluster, sort and keep extrachromosomal DNA -- like transfected plasmid DNA and endogenous circular DNAs originating from telomeres of the chromosome -- away from chromosomal DNA. That suggests that there is a cell autonomous genome defense system.

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A new machine-learning approach helps scientists more efficiently identify the optimal intervention to achieve a certain outcome in a complex system, such as genome regulation, requiring far fewer experimental trials than other methods. 

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By genetically testing nearly one thousand embryos, scientists have provided the most detailed analysis of embryo fate following human in vitro fertilization.

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New research suggests that ultrasound may have potential in treating a group of harmful chemicals known as PFAS to eliminate them from contaminated groundwater.

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Surprising findings on the development of sea anemones suggest that a predatory lifestyle molded their evolution and had a significant impact on the origin of their nervous system. The researchers were able to show that the young life stages (larvae) of the small sea anemone Aiptasia actively feed on living prey and are not dependent on algae. To capture its prey, the anemone larvae use specialized stinging cells and a simple neuronal network.

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The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin to cause disfiguring disease, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.