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Categories: Biology: Developmental, Computer Science: General

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A team of computer scientists recently unveiled a prize-winning Python profiler called Scalene. Programs written with Python are notoriously slow -- up to 60,000 times slower than code written in other programming languages -- and Scalene works to efficiently identify exactly where Python is lagging, allowing programmers to troubleshoot and streamline their code for higher performance.

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Findings can open up new avenues for targeted approaches toward therapeutic strategies against the malaria-causing P. falciparum that are aimed at stopping the parasite's life cycle progression and its sexual differentiation, thus blocking the transmission of the parasite into mosquitoes.

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Researchers have implemented a quantum-based method to observe a quantum effect in the way light-absorbing molecules interact with incoming photons. Known as a conical intersection, the effect puts limitations on the paths molecules can take to change between different configurations. The observation method makes use of a quantum simulator, developed from research in quantum computing, and offers an example of how advances in quantum computing are being used to investigate fundamental science.

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Researchers have succeeded in transforming brain signals into audible speech. By decoding signals from the brain through a combination of implants and AI, they were able to predict the words people wanted to say with an accuracy of 92 to 100%.

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Researchers have developed and demonstrated a new method for high-throughput single-cell sorting that uses stimulated Raman spectroscopy rather than the traditional approach of fluorescence-activated cell sorting. The new approach could offer a label-free, nondestructive way to sort cells for a variety of applications, including microbiology, cancer detection and cell therapy.

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The NSL (non-specific lethal) complex regulates thousands of genes in fruit flies and mammals. Silencing the NSL genes leads to the death of the organism, which gave the complex its curious name. Researchers have now discovered that the genes regulated by the NSL complex also include genes of the intraciliary transport system. This enables different cell types to form cilia on their surface, which are important for cell communication. The study shows that these genes are 'switched on' by the NSL complex, regardless of whether a particular cell has cilia or not. The researchers found that this class of cilia-associated genes is crucial for the function of podocytes. This is a highly specialized cell type of the kidney that, paradoxically, does not have cilia. These findings have important implications for ciliopathies and kidney disease.

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Researchers see potential in educational settings for the newest official ChatGPT plugin, called Code Interpreter, they've found limitations for its use by scientists who work with biological data utilizing computational methods to prioritize targeted treatment for cancer and genetic disorders.

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A new AI technique enables a robot to develop complex plans for manipulating an object using its entire hand, not just fingertips. This model can generate effective plans in about a minute using a standard laptop.

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A bitter taste in the mouth is often a symptom or side effect of illness, which may be the result of how the body reacts to pathogens. A new study sheds light on the mechanisms involved in the complex interplay between taste perception and immune function. Their work also highlights the potential of a sequencing tool for investigating epigenetic mechanisms that affect taste-cell gene expression.

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Researchers have discovered a novel approach for engrafting engineered cells into injured lung tissue. These findings may lead to new ways for treating lung diseases, such as emphysema, pulmonary fibrosis and COVID-19. The two studies describe the methodologies for engineering lung stem cells and transplanting them into injured experimental lungs without immunosuppression.

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In the form of DNA, nature shows how data can be stored in a space-saving and long-term manner. Bioinformatics specialists are developing DNA chips for computer technology. Researchers show how a combination of molecular biology, nanotechnology, novel polymers, electronics and automation, coupled with systematic development, could make DNA data storage useful for everyday use possible in a few years.

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Researchers have discovered how proteins work in tandem to regulate 'treadmilling', a mechanism used by the network of microtubules inside cells to ensure proper cell division.

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Researchers have designed a new type of quantum computer that uses fermionic atoms to simulate complex physical systems. The processor uses programmable neutral atom arrays and is capable of simulating fermionic models in a hardware-efficient manner using fermionic gates. The team demonstrated how the new quantum processor can efficiently simulate fermionic models from quantum chemistry and particle physics.

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Regulatory genes -- genes that control how other genes are used -- are responsible for 69% of the heritability of dairy cattle traits such as milk production and fertility, according to a new study. This contribution is 44% more than expected and much higher than previous studies of regulatory genes in humans. The findings, reported by a team of animal and human geneticists, could improve the efficiency of agricultural breeding programs. The study also helps solve the longstanding mystery of why mammalian genomes contain so much noncoding DNA.

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Researchers have developed a brain-computer interface (BCI) that has enabled a woman with severe paralysis from a brainstem stroke to speak through a digital avatar.

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Which structures do complex proteins adopt in solution? Biophysicists answer this question using the example of ubiquitin dimers as well as a new combination of high-resolution NMR spectroscopy and sophisticated computer simulations.

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Researchers have developed a platform that uses artificial neural networks to translate chemical structural formulae into machine-readable form. With this platform, they have created a tool with which this information from scientific publications can be automatically fed into databases. Until now, this had to be done literally by hand and was time-consuming.

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Researchers model and map how neurons across the tiny brain of a C. elegans worm encode its behaviors, revealing many new insights about the robustness and flexibility of its nervous system.

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Genetic remnants of viruses that are naturally present in the human genome could affect the development of neurodegenerative diseases. Researchers come to this conclusion on the basis of studies on cell cultures.

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Quantum physicists have successfully simulated super diffusion in a system of interacting quantum particles on a quantum computer. This is the first step in doing highly challenging quantum transport calculations on quantum hardware and, as the hardware improves over time, such work promises to shed new light in condensed matter physics and materials science.