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Categories: Biology: Developmental, Computer Science: Encryption
Published Basic 'toolkit' for organ development is illuminated by sea star



One of the basic and crucial embryonic processes to unfold in virtually every living organism is the formation of hollow, tubular structures that go on to form blood vessels or a digestive tract, and through branching and differentiation, complex organs including the heart and kidneys. This study illuminates fundamental design principles of tubulogenesis for all chordates, including mammals.
Published T cells can activate themselves to fight tumors



Scientists find an auto-signaling mechanism driving the T cell anti-tumor response; findings may inspire new cancer therapeutics and biomarkers.
Published An unprecedented view of gene regulation



Using a new technique, researchers have shown that they can map interactions between gene promoters and enhancers with 100 times higher resolution than has previously been possible.
Published Elucidating the mysteries of enzyme evolution at the macromolecular level



Researchers have made a major breakthrough earlier this year in the field of evolutionary conservation of molecular dynamics in enzymes. Their work points to potential applications in health, including the development of new drugs to treat serious diseases such as cancer or to counter antibiotic resistance.
Published The evolution of honey bee brains



Researchers have proposed a new model for the evolution of higher brain functions and behaviors in the Hymenoptera order of insects. The team compared the Kenyon cells, a type of neuronal cell, in the mushroom bodies (a part of the insect brain involved in learning, memory and sensory integration) of 'primitive' sawflies and sophisticated honey bees. They found that three diverse, specialized Kenyon cell subtypes in honey bee brains appear to have evolved from a single, multifunctional Kenyon cell-subtype ancestor. In the future, this research could help us better understand the evolution of some of our own higher brain functions and behaviors.
Published Happy worms have healthy eggs



Researchers have exposed roundworms (a well-established model organism in biological research) to selective serotonin reuptake inhibitors (SSRIs), a class of drugs used for treating depression and anxiety. Surprisingly, this treatment improved the quality of aging females' egg cells.
Published Scientists discover the dynamics of an 'extra' chromosome in fruit flies



Most chromosomes have been around for millions of years. Now, researchers have revealed the dynamics of a new, very young chromosome in fruit flies that is similar to chromosomes that arise in humans and is associated with treatment-resistant cancer and infertility. The findings may one day lead to developing more targeted therapies for treating these conditions.
Published A novel stem cell adhesive using mussels



A team of researchers develops stem cell adhesive for arthritis treatment using mussel adhesion protein and hyaluronic acid.
Published Scientists present evidence for a billion-years arms race between viruses and their hosts



Researchers have proposed a new evolutionary model for the origin of a kingdom of viruses called Bamfordvirae, suggesting a billion-years evolutionary arms race between two groups within this kingdom and their hosts.
Published Do people and monkeys see colors the same way?



New findings in color vision research imply that humans can perceive a greater range of blue tones than monkeys do. Distinct connections found in the human retina may indicate recent evolutionary adaptations for sending enhanced color vision signals from the eye to the brain.
Published Scientists slow aging by engineering longevity in cells



Researchers have developed a biosynthetic 'clock' that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.
Published Information 'deleted' from the human genome may be what made us human



What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard. The new findings, published April 28 in the journal Science, fill an important gap in what is known about historical changes to the human genome.
Published Mammalian evolution provides hints for understanding the origins of human disease



Even though it is important to know where these variations are located in the genome, it's also useful to know how or why these genetic variations happened in the first place.
Published Brain circuits for locomotion evolved long before appendages and skeletons



Scientists found parallels between the neural circuitry that guides locomotion in sea slugs and in more complex animals like mammals.
Published Researchers reveal an ancient mechanism for wound repair



The study is the first to identify a damage response pathway that is distinct from but parallel to the classical pathway triggered by pathogens.
Published Algae in Swedish lakes provide insights to how complex life on Earth developed



By studying green algae in Swedish lakes, a research team has succeeded in identifying which environmental conditions promote multicellularity. The results give us new clues to the amazing paths of evolution.
Published Fungal genetics could help develop novel biotechnologies



An essential pillar of Earth's ecological system, fungi have long been used to better the lives of humans. While these organisms are still vastly understudied, a new review paper suggests that their unique genomes could be used to make progress in the biotech industry.
Published Engineering the next generation of cell and gene therapies



Investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.
Published Study links 'stuck' stem cells to hair turning gray



Certain stem cells have a unique ability to move between growth compartments in hair follicles, but get stuck as people age and so lose their ability to mature and maintain hair color, a new study shows.
Published Loops, flags and tension in DNA



Two protein complexes carry the major responsibility for the spatial organization of chromosomes in our cell nuclei. DNA tension plays a surprising role in this. Nanoscientists now publish how they have visualized this.