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Categories: Biology: Developmental, Computer Science: Encryption
Published New mechanism for DNA folding



A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.
Published Biologists determine the evolutionary age of individual cell types providing critical insights for animal development



A research team has recently made a significant discovery about the evolutionary age of different type of cells in a small animal called Caenorhabditis elegans (C. elegans). By using single-cell transcriptomic data and refined phylostratigraphy, the team determines the transcriptomic age of individual cells, which means they are able to estimate the evolutionary origin of different cells based on the age of the genes expressed in the cells.
Published How skates learned to fly through water



Genes are not the only drivers of evolution. The iconic fins of skates are caused by changes in the non-coding genome and its three-dimensional structure, an international research team reports.
Published Oral barrier is similar in ceramide composition to skin barrier



Acylceramides and protein-bound ceramides are vital for the formation of the oral barrier in mice, similar to their role in skin, protecting from infection.
Published Genes are read faster and more sloppily in old age



Scientists have demonstrated the following findings which apply across the animal kingdom: with increasing age, the transcriptional elongation speed of genes increases, whereby the quality of the gene products suffers. With dietary restrictions, these processes could be reversed.
Published Stowaways in the genome



Scientists have discovered over 30,000 viruses by using the high-performance computer cluster 'Leo' and sophisticated detective work. The viruses hide in the DNA of unicellular organisms. In some cases, up to 10% of microbial DNA consists of built-in viruses.
Published Male yellow crazy ants are real-life chimeras



Researchers discovered that males of the yellow crazy ant have maternal and paternal genomes in different cells of their body and are thus chimeras.
Published Jellyfish and fruit flies shed light on the origin of hunger regulation



To survive, all organisms must regulate their appetite. Hormones and small proteins called neuropeptides perform this process, stimulating feelings of hunger and fullness. When researchers noted the similarities between GAWamide, a neuropeptide that regulates feeding in the Cladonema jellyfish, and myoinhibitory peptide, a neuropeptide that regulates feeding in fruit flies, they decided to test whether they could exchange the two. Their success in doing so highlights the deep evolutionary origins of feeding regulation.
Published Engineered plants produce sex perfume to trick pests and replace pesticides



Tobacco plants have been engineered to manufacture an alluring perfume of insect sex pheromones, which could be used to confuse would-be pests looking for love and reduce the need for harmful pesticides.
Published Here's how a worm's embryonic cells changed its development potential



Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary information for cell differentiation is mostly ingrained within DNA and other genetic factors.
Published Simple but revolutionary modular organoids



A team has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without using elaborate techniques. The group also recently demonstrated the ability to use the device to build organoids that faithfully reproduce the asymmetric genetic expression that characterizes the actual development of organisms.
Published Researchers clear the way for well-rounded view of cellular defects



New research investigates how cells divide, particularly in the fibrous environment of living tissue. Cells are typically studied in a flat environment, and the difference between flat and fibrous landscapes opens new windows into the behavior of cells and the diseases that impact them.
Published Researchers create embryo-like structures from monkey embryonic stem cells



Human embryo development and early organ formation remain largely unexplored due to ethical issues surrounding the use of embryos for research as well as limited availability of materials to study. Investigators now report on the creation of embryo-like structures from monkey embryonic stem cells. The investigators also transferred these embryo-like structures into the uteruses of female monkeys and determined that the structures were able to implant and elicit a hormonal response similar to pregnancy.
Published A miniature heart in a petri dish: Organoid emulates development of the human heart



A team has induced stem cells to emulate the development of the human heart. The result is a sort of 'mini-heart' known as an organoid. It will permit the study of the earliest development phase of our heart and facilitate research on diseases.
Published New cyber software can verify how much knowledge AI really knows



With a growing interest in generative artificial intelligence (AI) systems worldwide, researchers have created software that is able to verify how much information an AI farmed from an organization's digital database.
Published Study to decode microbe-gut signaling suggests potential new treatment for IBD



Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.
Published Microrobot technology: Externally connecting in vivo neural networks


Researchers have developed a technology for delivering a microrobot to a target point of a hippocampus in an in-vitro environment, connecting neural networks, and measuring neural signals. The findings are expected to contribute to neural network research and the verification and analysis of cell therapy products.
Published Boosting the body's anti-viral immune response may eliminate aging cells



Aging cells express a protein that is produced by human cytomegalovirus and is targeted by certain immune cells in the body. Harnessing the immune response to this protein could have multiple health benefits during aging.
Published T cells in human blood secrete a substance that affects blood pressure and inflammation



Acetylcholine regulates blood flow, but the source of blood acetylcholine has been unclear. Now, researchers have discovered that certain T cells in human blood can produce acetylcholine, which may help regulate blood pressure and inflammation. The study also demonstrates a possible association between these immune cells in seriously ill patients and the risk of death.
Published Components of cytoskeleton strengthen effect of sex hormones


Researchers discover that actin acts in the cell nucleus and is partly responsible for the expression of male sexual characteristics.