Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

New mechanism for DNA folding      (via sciencedaily.com)     Original source 

A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Biologists determine the evolutionary age of individual cell types providing critical insights for animal development      (via sciencedaily.com)     Original source 

A research team has recently made a significant discovery about the evolutionary age of different type of cells in a small animal called Caenorhabditis elegans (C. elegans). By using single-cell transcriptomic data and refined phylostratigraphy, the team determines the transcriptomic age of individual cells, which means they are able to estimate the evolutionary origin of different cells based on the age of the genes expressed in the cells.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Ecology: Sea Life
Published

How skates learned to fly through water      (via sciencedaily.com)     Original source 

Genes are not the only drivers of evolution. The iconic fins of skates are caused by changes in the non-coding genome and its three-dimensional structure, an international research team reports.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Genetics Biology: Molecular
Published

Oral barrier is similar in ceramide composition to skin barrier      (via sciencedaily.com)     Original source 

Acylceramides and protein-bound ceramides are vital for the formation of the oral barrier in mice, similar to their role in skin, protecting from infection.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Genes are read faster and more sloppily in old age      (via sciencedaily.com)     Original source 

Scientists have demonstrated the following findings which apply across the animal kingdom: with increasing age, the transcriptional elongation speed of genes increases, whereby the quality of the gene products suffers. With dietary restrictions, these processes could be reversed.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology
Published

Stow­aways in the genome      (via sciencedaily.com)     Original source 

Scientists have discovered over 30,000 viruses by using the high-performance computer cluster 'Leo' and sophisticated detective work. The viruses hide in the DNA of unicellular organisms. In some cases, up to 10% of microbial DNA consists of built-in viruses.

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Published

Jellyfish and fruit flies shed light on the origin of hunger regulation      (via sciencedaily.com)     Original source 

To survive, all organisms must regulate their appetite. Hormones and small proteins called neuropeptides perform this process, stimulating feelings of hunger and fullness. When researchers noted the similarities between GAWamide, a neuropeptide that regulates feeding in the Cladonema jellyfish, and myoinhibitory peptide, a neuropeptide that regulates feeding in fruit flies, they decided to test whether they could exchange the two. Their success in doing so highlights the deep evolutionary origins of feeding regulation.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Biology: Zoology
Published

Here's how a worm's embryonic cells changed its development potential      (via sciencedaily.com)     Original source 

Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary information for cell differentiation is mostly ingrained within DNA and other genetic factors.

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Published

Simple but revolutionary modular organoids      (via sciencedaily.com)     Original source 

A team has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without using elaborate techniques. The group also recently demonstrated the ability to use the device to build organoids that faithfully reproduce the asymmetric genetic expression that characterizes the actual development of organisms.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Researchers clear the way for well-rounded view of cellular defects      (via sciencedaily.com)     Original source 

New research investigates how cells divide, particularly in the fibrous environment of living tissue. Cells are typically studied in a flat environment, and the difference between flat and fibrous landscapes opens new windows into the behavior of cells and the diseases that impact them.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Offbeat: General Offbeat: Plants and Animals
Published

Researchers create embryo-like structures from monkey embryonic stem cells      (via sciencedaily.com)     Original source 

Human embryo development and early organ formation remain largely unexplored due to ethical issues surrounding the use of embryos for research as well as limited availability of materials to study. Investigators now report on the creation of embryo-like structures from monkey embryonic stem cells. The investigators also transferred these embryo-like structures into the uteruses of female monkeys and determined that the structures were able to implant and elicit a hormonal response similar to pregnancy.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Offbeat: General Offbeat: Plants and Animals
Published

A miniature heart in a petri dish: Organoid emulates development of the human heart      (via sciencedaily.com)     Original source 

A team has induced stem cells to emulate the development of the human heart. The result is a sort of 'mini-heart' known as an organoid. It will permit the study of the earliest development phase of our heart and facilitate research on diseases.

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Published

New cyber software can verify how much knowledge AI really knows      (via sciencedaily.com)     Original source 

With a growing interest in generative artificial intelligence (AI) systems worldwide, researchers have created software that is able to verify how much information an AI farmed from an organization's digital database.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Study to decode microbe-gut signaling suggests potential new treatment for IBD      (via sciencedaily.com)     Original source 

Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Molecular Chemistry: Biochemistry Engineering: Robotics Research
Published

Microrobot technology: Externally connecting in vivo neural networks      (via sciencedaily.com) 

Researchers have developed a technology for delivering a microrobot to a target point of a hippocampus in an in-vitro environment, connecting neural networks, and measuring neural signals. The findings are expected to contribute to neural network research and the verification and analysis of cell therapy products.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Microbiology Biology: Molecular
Published

Boosting the body's anti-viral immune response may eliminate aging cells      (via sciencedaily.com)     Original source 

Aging cells express a protein that is produced by human cytomegalovirus and is targeted by certain immune cells in the body. Harnessing the immune response to this protein could have multiple health benefits during aging.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: General
Published

T cells in human blood secrete a substance that affects blood pressure and inflammation      (via sciencedaily.com)     Original source 

Acetylcholine regulates blood flow, but the source of blood acetylcholine has been unclear. Now, researchers have discovered that certain T cells in human blood can produce acetylcholine, which may help regulate blood pressure and inflammation. The study also demonstrates a possible association between these immune cells in seriously ill patients and the risk of death.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

Components of cytoskeleton strengthen effect of sex hormones      (via sciencedaily.com) 

Researchers discover that actin acts in the cell nucleus and is partly responsible for the expression of male sexual characteristics.