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Categories: Biology: Developmental, Computer Science: Quantum Computers

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Scientists have revealed a never-before-seen phenomenon in a protein: Alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound to help bacteria commit suicide.

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A team has realized a key milestone in the quest for stable, scalable quantum computing. For the first time, the team has created a programmable, logical quantum processor, capable of encoding up to 48 logical qubits, and executing hundreds of logical gate operations. Their system is the first demonstration of large-scale algorithm execution on an error-corrected quantum computer, heralding the advent of early fault-tolerant, or reliably uninterrupted, quantum computation.

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The complexity of living organisms is encoded within their genes, but where do these genes come from? Researchers resolved outstanding questions regarding the origin of small regulatory genes, and described a mechanism that creates their DNA palindromes. Under suitable circumstances, these palindromes evolve into microRNA genes.

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Researchers have discovered that electric eels can alter the genes of tiny fish larvae with their electric shock. Their findings help to better understand electroporation, a method by which genes can be transported using electricity.

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Researchers have discovered magnetic monopoles -- isolated magnetic charges -- in a material closely related to rust, a result that could be used to power greener and faster computing technologies.

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Researchers have developed a new technique called MAbID. This allows them to simultaneously study different mechanisms of gene regulation, which plays a major role in development and disease. MAbID offers new insights into how these mechanisms work together or against each other.

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Long before researchers discovered the electron and its role in generating electrical current, they knew about electricity and were exploring its potential. One thing they learned early on was that metals were great conductors of both electricity and heat. And in 1853, two scientists showed that those two admirable properties of metals were somehow related: At any given temperature, the ratio of electronic conductivity to thermal conductivity was roughly the same in any metal they tested. This so-called Wiedemann-Franz law has held ever since -- except in quantum materials. Now, a theoretical argument put forth by physicists suggests that the law should, in fact, approximately hold for one type of quantum material, the cuprate superconductors.

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Researchers have uncovered a mechanism that safeguards the biallelic expression of haploinsufficient genes, shedding light on the importance of having two copies of each chromosome. A study identified the epigenetic regulator MSL2 an 'anti-monoallelic' factor that maintains biallelic gene dosage. This discovery not only reveals a communication system between parental alleles but also points to potential therapeutic strategies for diseases associated with haploinsufficient genes.

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Scientists have developed a new tool for the measurement of entanglement in many-body systems and demonstrated it in experiments. The method enables the study of previously inaccessible physical phenomena and could contribute to a better understanding of quantum materials.

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The evolution of higher cognitive functions in humans has so far mostly been linked to the expansion of the neocortex. Researchers are increasingly realizing, however, that the 'little brain' or cerebellum also expanded during evolution and probably contributes to the capacities unique to humans. A research team has now generated comprehensive genetic maps of the development of cells in the cerebella of human, mouse and opossum. Comparisons of these maps reveal both ancestral and species-specific cellular and molecular characteristics of cerebellum development.

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A new kind of 'wire' for moving excitons could help enable a new class of devices, perhaps including room temperature quantum computers.

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A research team shows how the expression of developmental genes in the Japanese green syllid worms, Megasyllis nipponica, helps form their swimming reproductive unit called stolon.  

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Trans-vaccenic acid (TVA), a long-chain fatty acid found in meat and dairy products from grazing animals such as cows and sheep, improves the ability of CD8+ T cells to infiltrate tumors and kill cancer cells, according to a new study.

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A new analysis sheds light on the molecular processes involved when a carnivorous species of fungus known as Arthrobotrys oligospora senses, traps and consumes a worm.

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Unlike humans, zebrafish can completely regenerate their hearts after injury. They owe this ability to the interaction between their nervous and immune systems, as researchers now report.

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Researchers have discovered a 'genomic tug of war' in animal studies that could influence how well certain patients -- or certain cancers -- respond to decitabine, a drug used to treat myelodysplastic syndromes that is plagued by drug resistance issues. For the first time, researchers show that decitabine causes coding and non-coding regions of DNA to engage in a tug of war for a gene activator, called H2A.Z. Typically, deticabine draws this gene activator away from coding DNA, causing gene expression to grind to a halt and cells to die. However, many types of cancer have very high levels of H2A.Z, which may help them overcome this decitabine-induced tug of war, allowing the cancer to grow.

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A new theoretical model helps explain how epigenetic memories, encoded in chemical modifications of chromatin, are passed from generation to generation.  Within each cell's nucleus, researchers suggest, the 3D folding patterns of its genome determines which parts of the genome will be marked by these chemical modifications.

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Researchers take a look at data that has so far been mostly discarded as contamination, revealing the previously underestimated role of extracellular vesicles (EVs). These are important for the exchange of genetic information between cells and thus for the microbial community in the sea.

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Newly discovered iron storage 'ferrosomes' inside the bacterium C. diff -- the leading cause of hospital-acquired infections -- are important for infection in an animal model and could offer new targets for antibacterial drugs. They also represent a rare demonstration of a membrane-bound structure inside a pathogenic bacterium, upsetting the biological dogma that bacteria do not contain organelles. 

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Distributed cloud storage is a hot topic for security researchers, and a team is now merging quantum physics with mature cryptography and storage techniques to achieve a cost-effective cloud storage solution.