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Categories: Biology: Developmental, Mathematics: Puzzles
Published Decoding the Easter Bunny -- an eastern Finnish brown hare to represent the standard for the species' genome



Biologists have published a chromosomally assembled reference genome for the European brown hare. The genome consists of 2.9 billion base pairs, which form 23 autosomal chromosomes, and X and Y sex chromosomes. The timing of the genome release is very appropriate as the brown hare also represents the original Easter Bunny familiar from European folklore.
Published Genes identified that allow bacteria to thrive despite toxic heavy metal in soil



Some soil bacteria can acquire sets of genes that enable them to pump the heavy metal nickel out of their systems, a study has found. This enables the bacteria to not only thrive in otherwise toxic soils but help plants grow there as well. A research team pinpointed a set of genes in wild soil bacteria that allows them to do this in serpentine soils which have naturally high concentrations of toxic nickel. The genetic discovery could help inform future bioremediation efforts that seek to return plants to polluted soils.
Published Where quantum computers can score



The traveling salesman problem is considered a prime example of a combinatorial optimization problem. Now a team has shown that a certain class of such problems can actually be solved better and much faster with quantum computers than with conventional methods.
Published How cells are ahead of the curve



The curvature of a surface determines the migration behavior of biological cells. They preferentially move along valleys or grooves while avoiding ridges. These findings gave rise to a model predicting cellular behavior. Such universal principles now allow a better understanding of the migration of immune and cancer cells, paving the way for new treatment options.
Published Machine learning classifier accelerates the development of cellular immunotherapies



Making a personalized T cell therapy for cancer patients currently takes at least six months. Scientists have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.
Published New study on mating behaviors offers clues into the evolution of attraction



In examining the mating rituals of roundworms, researchers uncovered a unique approach to reproduction that maximizes genetic fitness.
Published New discovery reveals how the egg controls sperm entry



After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo, a new study finds. The work also explains how mutations in egg coat proteins can cause female infertility and may eventually lead to new contraceptive methods.
Published Satellites for quantum communications



Through steady advances in the development of quantum computers and their ever-improving performance, it will be possible in the future to crack our current encryption processes. To address this challenge, researchers are developing encryption methods that will apply physical laws to prevent the interception of messages. To safeguard communications over long distances, the QUICK space mission will deploy satellites.
Published Milk to the rescue for diabetics? Cow produces human insulin in milk



An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.
Published How a natural compound from sea squirts combats cancer



Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.
Published Researchers uncover protein responsible for cold sensation



Researchers have identified the protein that enables mammals to sense cold, filling a long-standing knowledge gap in the field of sensory biology.
Published Research sheds light on new strategy to treat infertility



New research describes the science behind a promising technique to treat infertility by turning a skin cell into an egg that is capable of producing viable embryos. The technique could be used by women of advanced maternal age or for those who are unable to produce viable eggs due to previous treatment for cancer or other causes. It also raises the possibility of men in same-sex relationships having children who are genetically related to both parents.
Published New study discovers how altered protein folding drives multicellular evolution



Researchers have discovered a mechanism steering the evolution of multicellular life. They identified how altered protein folding drives multicellular evolution.
Published Mutation solves a century-old mystery in meiosis



A team deciphers complicated mechanism underlying genetic diversity.
Published Researchers develop artificial building blocks of life



For the first time, scientists have developed artificial nucleotides, the building blocks of DNA, with several additional properties in the laboratory.
Published Vitamin A may play a central role in stem cell biology and wound repair



Retinoic acid, the active state of Vitamin A, appears to regulate how stem cells enter and exit a transient state central to their role in wound repair.
Published How does a virus hijack insect sperm to control disease vectors and pests?



A widespread bacteria called Wolbachia and a virus that it carries can cause sterility in male insects by hijacking their sperm, preventing them from fertilizing eggs of females that do not have the same combination of bacteria and virus. A new study has uncovered how this microbial combination manipulates sperm, which could lead to refined techniques to control populations of agricultural pests and insects that carry diseases like Zika and dengue to humans.
Published The Malaria parasite generates genetic diversity using an evolutionary 'copy-paste' tactic



All modern Plasmodium falciparum, the deadliest malaria parasite in humans, are descendants of one initial infection and so are very closely related, with relatively limited genetic differences. A long-standing mystery in the field has revolved around a very few locations in the P. falciparum genome where there are 'spikes' of mutations -- far more than anywhere else. Researchers have identified two genes in which these unusual mutation spikes result from DNA being copied and pasted from one gene to another.
Published Cracking epigenetic inheritance: Biologists discovered the secrets of how gene traits are passed on



A research team has recently made a significant breakthrough in understanding how the DNA copying machine helps pass on epigenetic information to maintain gene traits at each cell division. Understanding how this coupled mechanism could lead to new treatments for cancer and other epigenetic diseases by targeting specific changes in gene activity.
Published Universal tool for tracking cell-to-cell interactions



An updated method for directly observing physical interactions between cells, could allow scientists to one day map every possible cell interaction.