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Categories: Biology: Developmental, Mathematics: General

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All modern Plasmodium falciparum, the deadliest malaria parasite in humans, are descendants of one initial infection and so are very closely related, with relatively limited genetic differences. A long-standing mystery in the field has revolved around a very few locations in the P. falciparum genome where there are 'spikes' of mutations -- far more than anywhere else. Researchers have identified two genes in which these unusual mutation spikes result from DNA being copied and pasted from one gene to another.

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A new safety-check technique can prove with 100 percent accuracy that a planned robot motion will not result in a collision. The method can generate a proof in seconds and does so in a way that can be easily verified by a human.

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A research team has recently made a significant breakthrough in understanding how the DNA copying machine helps pass on epigenetic information to maintain gene traits at each cell division. Understanding how this coupled mechanism could lead to new treatments for cancer and other epigenetic diseases by targeting specific changes in gene activity.

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Solving arithmetic problems, even simple subtractions, involves mental representations whose influence remains to be clarified. Visualizing these representations would enable us to better understand our reasoning and adapt our teaching methods. A team has now analyzed drawings made by children and adults when solving simple problems. The scientists found that, whatever the age of the participant, the most effective calculation strategies were associated with certain drawing typologies. These results open up new perspectives for the teaching of mathematics.

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An updated method for directly observing physical interactions between cells, could allow scientists to one day map every possible cell interaction.

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'Random DNA' is naturally active in the one-celled fungi yeast, while such DNA is turned off as its natural state in mammalian cells, despite their having a common ancestor a billion years ago and the same basic molecular machinery, a new study finds.

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Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected cells. A major study now provides important new insights into how complex epigenetic modification signatures regulate the genome. This study will pave the way for new treatments of diseases caused by faulty epigenetic machineries.

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Researchers developed protocols for growing organoids that mimic a turtle liver, the first organoids developed for a turtle and only the second for any reptile. The discovery will aid deeper study of turtle genetics, including the cause of traits with potential medical applications for humans such as the ability to survive weeks without oxygen.

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A new mathematical model has shown, with great precision, the impact that physiological and psychological parameters have on running performance and provides tips for optimized training.

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A globally distributed single-celled organism that occurs in harmful algal blooms has been found to exhibit an unusual organisation of photosynthesis. Researchers have taken a closer look at the unusual cell biology of the species Prorocentrum cordatum from the group of dinoflagellates. The results of their study could help to better understand the role of the species in the environment and the increased occurrence of algal blooms at higher water temperatures.

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A new paper examines the possible effects of two properties of receiver playing fields documented in studies of animal psychology -- habituation and neural adaptation -- on the efficacy of mate choice signals.

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Keratin microsphere gel, consisting of keratin-based microspheres that swell in water to form a gel, has shown efficacy in promoting hair follicle growth in murine models. Its potential application as an active ingredient in hair regrowth treatments with minimal side effects is anticipated.

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Researchers report that the Golgi ribbon, an organelle structure previously thought to be exclusive to vertebrates, is also present in animal taxa, including mollusks, earthworms, and sea urchins. The function of the Golgi ribbon is still enigmatic, but its presence in diverse animal lineages indicates that its function is not vertebrate specific, as previously thought. The team also showed Golgi ribbons form at a specific timepoint during embryogenesis, which suggests that they might play a role in cell differentiation.

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Scientists have found a new way to alter the DNA of bacterial cells -- a process used to make many vital medicines including insulin -- much more efficiently than standard industry techniques.

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New findings suggest the end-replication problem, an old standby of biology textbooks, is twice as intricate as once thought.

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A genetic change in our ancient ancestors may partly explain why humans don't have tails like monkeys.

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The tone and tuning of musical instruments has the power to manipulate our appreciation of harmony, new research shows. The findings challenge centuries of Western music theory and encourage greater experimentation with instruments from different cultures.

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Intelligent tutoring systems for math problems helped pupils remain or even increase their performance during the coronavirus pandemic, according to a new study. Researchers analyzed data from five million exercises done by around 2,700 pupils in Germany over a period of five years. The study found that particularly lower-performing children benefit if they use the software regularly.

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Decoding the conversations between microbes of hypersaline environments reveals deep insights into the origins of complex life.

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The first stem cell culture method that produces a full model of the early stages of the human central nervous system has been developed by a team of engineers and biologists.