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Categories: Biology: Developmental, Ecology: Extinction
Published Researchers pinpoint most likely source of HIV rebound infection
(via sciencedaily.com) Original source Antiretroviral therapy (ART) does an excellent job at suppressing HIV to undetectable levels in the blood. However, small amounts of latent virus hide throughout the body, and when treatment is stopped, it opens the door for the virus to rebound. Researchers identified which tissues SIV, the nonhuman primate version of HIV, reemerges from first, just seven days after ART is stopped.
Published World's first successful embryo transfer in rhinos paves the way for saving the northern white rhinos from extinction
(via sciencedaily.com) Original source Scientists have succeeded in achieving the world's first pregnancy of a rhinoceros after an embryo transfer. The southern white rhino embryo was produced in vitro from collected egg cells and sperm and transferred into a southern white rhino surrogate mother at the Ol Pejeta Conservancy in Kenya on September 24, 2023. The BioRescue team confirmed a pregnancy of 70 days with a well-developed 6.4 cm long male embryo. The successful embryo transfer and pregnancy are a proof of concept and allow to now safely move to the transfer of northern white rhino embryos -- a cornerstone in the mission to save the northern white rhino from extinction.
Published Ancient brown bear genomes sheds light on Ice Age losses and survival
(via sciencedaily.com) Original source The brown bear is one of the largest living terrestrial carnivores, and is widely distributed across the Northern Hemisphere. Unlike many other large carnivores that went extinct at the end of the last Ice Age (cave bear, sabretoothed cats, cave hyena), the brown bear is one of the lucky survivors that made it through to the present. The question has puzzled biologists for close to a century -- how was this so?
Published New tool reveals gene behavior in bacteria
(via sciencedaily.com) Original source Researchers showed that the way in which genes are turned on and off as bacteria grow provide clues to their regulation.
Published Study offers rare long-term analysis of techniques for creating standing dead trees for wildlife habitat
(via sciencedaily.com) Original source Ecologists have long known that standing dead trees, commonly referred to as snags, are an important habitat element for forest dwellers and act as a driver of biodiversity. They're so important that in some managed forests, snag creation is part of the conservation tool kit -- i.e., crews sometimes convert a percentage of live trees into dead ones through techniques ranging from sawing off their tops to wounding their trunks to injecting them with disease-causing fungi.
Published Three-year population study supports fight to save Cameroon's Kordofan giraffe
(via sciencedaily.com) Original source Crucial new data about the numbers of Critically Endangered Kordofan giraffe living within Cameroon's B nou National Park has been released, supporting conservation efforts to save the subspecies from extinction.
Published A new perspective on the temperature inside tropical forests
(via sciencedaily.com) Original source New worldwide maps of temperatures inside tropical forests show that global warming affect different way in different parts of the forests. Undergrowth level temperature of the tropical forests can be even 4 degrees less than average temperature of the area.
Published The megalodon was less mega than previously believed
(via sciencedaily.com) Original source A new study shows the Megalodon, a gigantic shark that went extinct 3.6 million years ago, was more slender than earlier studies suggested. This finding changes scientists' understanding of Megalodon behavior, ancient ocean life, and why the sharks went extinct.
Published Sea otters helped prevent widespread California kelp forest declines over the past century
(via sciencedaily.com) Original source The study reveals dramatic regional kelp canopy changes along the California coast over a 100-year period. During this time there was a significant increase in kelp forest canopy along the central coast, the only region of California where southern sea otters survived after being hunted nearly to extinction for their fur in the 1800s. Contrastingly, kelp canopy decreased in northern and southern regions. At the century scale, the species' favorable impact on kelp forests along the central coast nearly compensated for the kelp losses along both northern and southern California resulting in only a slight overall decline statewide during this period.
Published Scientists, farmers and managers work together to avoid the decline of the little bustard, an endangered steppe bird
(via sciencedaily.com) Original source The collaboration between scientists, farmers and managers is crucial to improve the protection of the little bustard, an endangered steppe-land bird in Spain due to human activity. The reduction of natural habitats, the increase in irrigation and the urbanization of the land have led to having less surface areas that guarantee the survival of this vulnerable species.
Published DNA construction led to unexpected discovery of important cell function
(via sciencedaily.com) Original source Researchers have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way. The result opens new avenues for understanding how the Notch signalling pathway works and how it is involved in several serious diseases.
Published Why animals shrink over time explained with new evolution theory
(via sciencedaily.com) Original source The new theoretical research proposes that animal size over time depends on two key ecological factors.
Published Study throws our understanding of gene regulation for a loop
(via sciencedaily.com) Original source To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.
Published Machine learning reveals sources of heterogeneity among cells in our bodies
(via sciencedaily.com) Original source A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.
Published Surprisingly simple model explains how brain cells organize and connect
(via sciencedaily.com) Original source A new study by physicists and neuroscientists describes how connectivity among neurons comes about through general principles of networking and self-organization, rather than the biological features of an individual organism.
Published New technology for conducting deep-sea research on fragile organisms
(via sciencedaily.com) Original source Scientists have successfully demonstrated new technologies that can obtain preserved tissue and high-resolution 3D images within minutes of encountering some of the most fragile animals in the deep ocean.
Published Bioinformatics: Researchers develop a new machine learning approach
(via sciencedaily.com) Original source To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.
Published 3D in vitro human atherosclerosis model for high-throughput drug screening
(via sciencedaily.com) Original source A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.
Published Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging
(via sciencedaily.com) Original source Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.
Published Aging mouse sperm affects MicroRNA, increasing the risk of neurodevelopmental disorders
(via sciencedaily.com) Original source Much is known about the added complication to pregnancy when it comes to the age of the mother, but recent studies show that the age of the father can also heighten the risk of neurodevelopmental disorders. A team of researchers has explored the impacts of paternal aging on microRNAs, the molecules that play a crucial role in regulating gene expression.