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Categories: Biology: Developmental, Space: Cosmology

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The annual killifish lives in regions with extreme drought. A research group now reports that the early embryogenesis of killifish diverges from that of other species. Unlike other fish, their body structure is not predetermined from the outset. This could enable the species to survive dry periods unscathed.

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Research reveals a shocking discovery about the history of our universe: the Milky Way Galaxy's last major collision occurred billions of years later than previously thought.

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In the first quintillionth of a second, the universe may have sprouted microscopic black holes with enormous amounts of nuclear charge, MIT physicists propose. The gravitational pull from these tiny, invisible objects could potentially explain all the dark matter that we can't see today.

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A groundbreaking method of detecting high-frequency gravitational waves (HFGWs) has been proposed. The team's innovative approach may enable the successful detection of HFGWs by utilizing existing and technologically feasible astronomical telescopes in planetary magnetosphere, opening up new possibilities for studying the early universe and violent cosmic events in an effective and technically viable way.

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Scientists have found that the process of adaptive myelination, which helps the brain learn new skills, can also promote addiction to opioids.

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Researchers invented a technique that allows them to observe which genes and enhancers are active in a cell at the same time. This could help them determine which enhancers control which genes and may reveal potential new drug targets for genetic disorders.

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A recent study provides new insights into how fathers' diets and overweight can affect their children's health even before conception. The findings of the study can help develop preventive health measures for men wishing to become fathers: The healthier the father's diet, the lower the risk for their children to develop obesity or diseases such as diabetes later in life.

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Biological processes depend on puzzle pieces coming together and interacting. Under specific conditions, these interactions can create something new without external input. This is called self-organization, as seen in a school of fish or a flock of birds. Interestingly, the mammalian embryo develops similarly. Scientists now introduce a mathematical framework that analyzes self-organization from a single cell to a multicellular organism.

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New research demonstrated a possible formation mechanism of intermediate-mass black holes in globular clusters, star clusters that could contain tens of thousands or even millions of tightly packed stars. The first ever star-by-star massive cluster-formation simulations revealed that sufficiently dense molecular clouds, the 'birthing nests' of star clusters, can give birth to very massive stars that evolve into intermediate-mass black holes.

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Over the last two years, scientists have used NASA's James Webb Space Telescope to explore what astronomers refer to as Cosmic Dawn -- the period in the first few hundred million years after the big bang where the first galaxies were born.

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Researchers have applied the well-understood and highly verified quantum field theory, usually applied to the study of the very small, to a new target, the early universe. Their exploration led to the conclusion that there ought to be far fewer miniature black holes than most models suggest, though observations to confirm this should soon be possible. The specific kind of black hole in question could be a contender for dark matter.

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The benefits gained with higher lifestyle scores may be associated with the positive influence of heart disease risk factors on the aging of the body and its cells, finds a new study in the Journal of the American Heart Association

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A new deep learning model performs a task that biologists have struggled with for centuries -- how to measure the incredibly complex process of embryonic development. Scientists have shown that the AI model, known as Dev-ResNet, can identify what happens and when during embryonic development, from video. While used in pond snail embryos for this study, in future the technique could be used to help accelerate understanding on how climate change, and other external factors, affect humans and animals in the earliest stages of life.

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Researchers have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.

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Researchers found that approximately one in 40 human bone marrow cells carry massive chromosomal alterations without causing any apparent disease or abnormality. Even so-called normal cells carry all sorts of genetic mutations, meaning there are more genetic differences between individual cells in our bodies than between different human beings. The discovery was enabled by a single-cell sequencing technology called Strand-seq, a unique DNA sequencing technique that can reveal subtle details of genomes in single cells that are too difficult to detect with other methods.

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Scientists have developed a new method that can manipulate the movement of embryonic cells using short-time attractors.

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The African turquoise killifish lives in ephemeral ponds in Zimbabwe and Mozambique. To survive the annual dry season, the fish's embryos enter a state of extreme suspended animation or 'diapause' for approximately 8 months. Now, researchers have uncovered the mechanisms that enabled the killifish to evolve this extreme survival state.

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While most organisms have biological clocks synchronized with the day-night cycle (circadian rhythms), marine animals in tidal areas have also developed circatidal rhythms to align with the tidal cycle. Comparing the activity and genetic expression of snails from tidal and non-tidal areas, researchers demonstrate that circatidal rhythms develop as snails adapt to tidal environments. These findings highlight the flexibility of biological clocks, enabling organisms to adjust their rhythms according to the environment.

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Researchers have now seen the formation of three of the earliest galaxies in the universe, more than 13 billion years ago. The sensational discovery contributes important knowledge about the universe.

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Biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new 'gene atlas' with 4-D imaging, the researchers captured unprecedented insights on how embryonic development unfolds.