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Categories: Biology: Developmental, Ecology: Animals
Published The future of canine stem cell therapy: unprecedented, painless, and feeder-free
(via sciencedaily.com) Original source Scientists have developed an efficient, non-invasive, and pain-free method to generate canine-induced pluripotent stem cells (iPSCs). They identified six reprogramming genes that can boost canine iPSC generation by 120 times compared to conventional methods using fibroblasts. The iPSCs were created from urine-derived cells without the need for feeder cells, an impossible feat until now. Their findings are expected to advance regenerative medicine and genetic disease research in veterinary medicine.
Published Insects already had a variety of defense strategies in the Cretaceous
(via sciencedaily.com) Original source Analyses of amber show that insect larvae were already using a wide variety of tactics to protect themselves from predators 100 million years ago.
Published Bugs that help bugs: How environmental microbes boost fruit fly reproduction
(via sciencedaily.com) Original source A research group found that in female fruit flies, microorganisms enhance reproductive function, boosting the number of cells that form eggs and the number of mature eggs. This is done by controlling the release of hormones to speed up cell division in the ovaries, and limiting programmed cell death. These findings could improve reproductive medicine and could aid the development of new methods to enhance fertility.
Published Researchers solve mystery behind DnaA protein's role in DNA replication initiation
(via sciencedaily.com) Original source Scientists have uncovered how DnaA, the master key to DNA replication, opens the door to bacterial growth. This breakthroughpaves the way for new antibiotics to combat the rising tide of antibiotic resistance.
Published New insights revealed on tissue-dependent roles of JAK signaling in inflammation
(via sciencedaily.com) Original source Researchers have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.
Published How researchers are 'CReATiNG' synthetic chromosomes faster and cheaper
(via sciencedaily.com) Original source A new technique to clone and reassemble DNA, dubbed CReATiNG, could simplify and lower the cost to make synthetic chromosomes. Potential applications are numerous, including pharmaceutical production, biofuel generation, cancer therapies, and environmental cleanup using modified organisms. The method adds a powerful, versatile tool to the burgeoning field of synthetic biology.
Published A trillion scents, one nose
(via sciencedaily.com) Original source A research team has uncovered a previously undetected mechanism in mice -- starring the genetic molecule RNA -- that could explain how each sensory cell, or neuron, in mammalian noses becomes tailored to detect a specific odor chemical.
Published Cells of the future: A key to reprogramming cell identities
(via sciencedaily.com) Original source The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time. Scientists have recently uncovered a fascinating aspect of this process known as 'replication timing' (RT) and how special this is when life commences.
Published New study examines the relationship between the rate of wound healing, the circadian rhythm, and 'hair' on cells
(via sciencedaily.com) Original source Nearly every organism on Earth follows a natural circadian rhythm that is coded by your cell's clock genes, which do exactly as you suspect from the name: regulate your body's rhythm on a 24-hour basis. Most cells in mammalian bodies have cilia of some sort, which are hair-like structures that perform a variety of functions such as movement for motile cilia and aiding in structure in function for non-motile, or primary, cilia. The primary cilia also act as a sensory organ for the cell, a function which has illuminated the primary cilia's potential role in the healing process and how bodies heal at a different rate according to our circadian rhythm. In this research, the role of the primary cilia, biological clock and wound healing is explored.
Published Single-celled protists in the guts of animals thrive without the 'powerhouse of the cell'
(via sciencedaily.com) Original source Almost all eukaryotic organisms, from plants and animals to fungi, can't survive without mitochondria -- the 'powerhouses of the cell,' which generate chemical energy using oxygen. However, a new study finds that multiple members of the oxymonads, a group of single-celled protists that live inside the guts of termites and other animals, have evolved to live quite happily without them.
Published Genetic diversity of wild north American grapes mapped
(via sciencedaily.com) Original source Wild North American grapes are now less of a mystery after researchers decoded and catalogued the genetic diversity of nine species of this valuable wine crop.
Published Genetics of host plants determine what microorganisms they attract
(via sciencedaily.com) Original source Plants often develop communities with microorganisms in their roots, which influences plant health and development. Although the recruitment of these microbes is dictated by several factors, it is unclear whether the genetic variation in the host plants plays a role.
Published Study uncovers major hidden human-driven bird extinctions
(via sciencedaily.com) Original source Humans have wiped out around 1,400 bird species -- twice as many as previously thought -- with major implications for the ongoing biodiversity crisis, a new study has found. The estimated extinctions would mean almost 12 per cent of bird species have died out over modern human history, since the Late Pleistocene around 130,000 years ago, with the vast majority of them becoming extinct directly or indirectly due to human activity.
Published Global inventory of sound production brings us one step closer to understanding aquatic ecosystems
(via sciencedaily.com) Original source Our understanding of which aquatic species produce sounds just took a big step forward. Scientists have created an inventory of species confirmed or expected to produce sound underwater.
Published Hotter weather caused by climate change could mean more mosquitoesv
(via sciencedaily.com) Original source Research along James River in Richmond suggests that climate change could shorten window for predators to prey on larvae.
Published Scientists collect aardvark poop to understand how the species is impacted by climate in Africa
(via sciencedaily.com) Original source In a new study of aardvarks, researchers spent months in sub-Saharan Africa collecting poop from the animal and concluded that aridification of the landscape is isolating them, which they say could have implications for their long-term survival.
Published New method could help estimate wildlife disease spread
(via sciencedaily.com) Original source A new method could be used to estimate the prevalence of disease in free-ranging wildlife and help determine how many samples are needed to detect a disease.
Published Genetic atlas detailing early stages of zebrafish development
(via sciencedaily.com) Original source Researchers have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a period in which embryos mature from a single cell into distinct cell types.
Published Can you change a chicken into a frog, a fish or a chameleon?
(via sciencedaily.com) Original source Researchers have developed a theoretical framework that can reproduce and predict the patterns associated with gastrulation in a chicken embryo.
Published How the immune system fights to keep herpes at bay
(via sciencedaily.com) Original source In a study of lab-engineered cells, researchers identify how the immune system neutralizes the herpesvirus. The research maps, for the first time, the maneuvers used by virus and host in the cell nucleus, a poorly understood terrain of host-pathogen interaction. The findings could inform the design of new treatments for herpes and other viruses that replicate in the same way.