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Categories: Biology: Developmental, Ecology: Invasive Species
Published Preventing spread of parasitic DNA in our genomes



Researchers have identified a new enzyme called PUCH, which plays a key role in preventing the spread of parasitic DNA in our genomes. These findings may reveal new insights into how our bodies detect and fight bacteria and viruses to prevent infections.
Published A hygiene program for chromosomes



Researchers identified and characterized a new cellular compartment in vertebrate cells that might be a precursor of today's eucaryotic nucleus. The study reveals that mammalian cells recognize, cluster, sort and keep extrachromosomal DNA -- like transfected plasmid DNA and endogenous circular DNAs originating from telomeres of the chromosome -- away from chromosomal DNA. That suggests that there is a cell autonomous genome defense system.
Published A more effective experimental design for engineering a cell into a new state



A new machine-learning approach helps scientists more efficiently identify the optimal intervention to achieve a certain outcome in a complex system, such as genome regulation, requiring far fewer experimental trials than other methods.
Published Researchers studied thousands of fertility attempts hoping to improve IVF



By genetically testing nearly one thousand embryos, scientists have provided the most detailed analysis of embryo fate following human in vitro fertilization.
Published Timing plant evolution with a fast-ticking epigenetic clock



Recent discoveries in the field of epigenetics, the study of inheritance of traits that occur without changing the DNA sequence, have shown that chronological age in mammals correlates with epigenetic changes that accumulate during the lifetime of an individual. In humans, this observation has led to the development of epigenetic clocks, which are now extensively used as biomarkers of aging. While these clocks work accurately from birth until death, they are set back to zero in each new generation. Now, an international team shows that epigenetic clocks not only exist in plants, but that these clocks keep ticking accurately over many generations.
Published Did animal evolution begin with a predatory lifestyle?



Surprising findings on the development of sea anemones suggest that a predatory lifestyle molded their evolution and had a significant impact on the origin of their nervous system. The researchers were able to show that the young life stages (larvae) of the small sea anemone Aiptasia actively feed on living prey and are not dependent on algae. To capture its prey, the anemone larvae use specialized stinging cells and a simple neuronal network.
Published A lethal parasite's secret weapon: Infecting non-immune cells



The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin to cause disfiguring disease, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.
Published Fish reveal cause of altered human facial development



Some substances in medicines, household items and the environment are known to affect prenatal child development. Researchers tested the effects of five drugs (including caffeine and the blood thinner warfarin) on the growth of zebrafish embryos. They found that all five had the same effect, impairing the migration of bone-forming cells which resulted in the onset of facial malformation. Zebrafish embryos grow quickly, are transparent and develop outside of the parent's body, making them ideal for studying early development. A zebrafish-based system could be used to easily screen for potentially harmful substances, reducing animal testing on mammals and supporting parents-to-be when making choices for themselves and their baby.
Published Vision in the brain: Hardwired for action



Brain circuits for vision develop without any kind of input from the retina in zebrafish.
Published New information on the most important early stage of embryonic development



A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development.
Published Tiny CRISPR tool could help shred viruses



Scientists mapped out the three-dimensional structure of one of the smallest known CRISPR-Cas13 systems then used that knowledge to modify its structure and improve its accuracy.
Published New research reveals dynamic factors shaping biodiversity at small scales



Researchers studying arboreal ants in a Florida forest explore the fundamental question of how resource availability and competition shape biodiversity.
Published How the heart starts beating



Researchers discover that heart cells in developing zebrafish start beating suddenly and all at once
Published Researchers discover disease-causing stem cells in lungs of cystic fibrosis patients



Experts in cloning and stem cell science are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis, and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.
Published How to save plants from climate change? Just ask them


Climate change and a range of human-caused factors have disrupted the habitats of many California native trees and other plant species. Efforts to protect or relocate plant species would be bolstered by understanding which habitats are best suited for each species. A new study identified a range of characteristics from more than 100 types of plants that can be analyzed to determine each species' preferred temperature and rainfall amount.
Published Decreasing biodiversity may promote spread of viruses



How are environmental changes, loss of biodiversity, and the spread of pathogens connected? The answer is a puzzle. Researchers have now described one piece of that puzzle, showing that the destruction of tropical rainforests harms the diversity of mosquito species. At the same time, more resilient species of mosquitoes become more prevalent -- which also means the viruses they carry are more abundant. If there are many individuals of a given species, those viruses can spread quickly.
Published Caribbean parrots thought to be endemic are actually relicts of millennial-scale extinction



For the first time, researchers have extracted ancient DNA from Caribbean parrot fossils and archaeological specimens, showing that species thought to be endemic to particular islands were historically more widespread and diverse.
Published Jellyfish, with no central brain, shown to learn from past experience



Even without a central brain, jellyfish can learn from past experiences like humans, mice, and flies, scientists report for the first time. They trained Caribbean box jellyfish (Tripedalia cystophora) to learn to spot and dodge obstacles. The study challenges previous notions that advanced learning requires a centralized brain and sheds light on the evolutionary roots of learning and memory.
Published Researchers develop first method to study microRNA activity in single cells


Researchers have developed the first method to uncover the tasks that microRNAs perform in single cells. This is a huge improvement over existing state-of-the-art methods that require millions of cells and will for the first time allow researchers to study microRNAs in complex tissues such as brains.
Published How climate warming could disrupt a deep-rooted relationship


Trees depend on fungi for their well-being. As climate change and global warming cause higher temperatures and amplified drought, little is known about how these important fungi will respond. To investigate this issue, a research team conducted a climate change experiment where they exposed boreal and temperate tree species to warming and drought treatments to better understand how fungi and their tree hosts respond to environmental changes. Their findings revealed that the combined effects of warming and water stress will likely result in major disturbances of ectomycorrhizal networks and may harm forest resilience and function.