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Categories: Biology: Developmental, Environmental: Wildfires
Published New study sheds light on the molecular mechanisms underlying lipid recycling within cells
(via sciencedaily.com) Original source Our understanding of how cells recycle lipids through autophagy -- a form of cellular degradation -- has grown significantly, thanks to a recent study. Using yeast as a model organism, the researchers explored the molecular mechanisms leading to the degradation of the phospholipid bilayers making up the cell membranes. Their findings improve our understanding of cellular degradation processes and related metabolic disorders.
Published First mice engineered to survive COVID-19 like young, healthy humans
(via sciencedaily.com) Original source Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a new study.
Published Where is a sea star's head? Maybe just about everywhere
(via sciencedaily.com) Original source A new study that combines genetic and molecular techniques helps solve the riddle of sea star (commonly called starfish) body plans, and how sea stars start life with bilateral body symmetry -- just like humans -- but grow up to be adults with fivefold 'pentaradial' symmetry.
Published Pinpointing HIV immune response
(via sciencedaily.com) Original source New research combining computer modeling and experiments with macaques shows the body's immune system helps control human immunodeficiency virus (HIV) infections largely by suppressing viral production in already infected cells while also killing viral infected cells, but only within a narrow time window at the start of a cell's infection.
Published Maternal microbiota can affect fetal development
(via sciencedaily.com) Original source Significant differences in the gene activity of the fetal intestine, brain and placenta were identified, depending on the microbes in the mother's body and the compounds produced by them. The findings indicate that maternal microbes are important to her offspring's development and health.
Published New Nijmegen method reveals hidden genetic variations
(via sciencedaily.com) Original source Many hidden genetic variations can be detected with Chameleolyser, a new method. The information is already yielding new patient diagnoses and may also lead to the discovery of as yet unknown disease genes.
Published Advanced assisted reproduction in white rhinos is safe and reliable, shows evaluation of procedures
(via sciencedaily.com) Original source The BioRescue project develops and pioneers advanced assisted reproduction technologies (aART) for conservation in the face of the imminent extinction of most rhino species and subspecies. In a new scientific analysis, the team evaluated 65 aART procedures conducted from 2015 to 2022. The evaluation showed that aART is safe for the donor females with no detrimental health effects, and successful in that it yielded 51 embryos.
Published Scientists create special 'telomouse' with human-like telomeres
(via sciencedaily.com) Original source Researchers introduce the 'Telomouse'. By making a subtle genetic alteration in standard lab mice, they've made the mouse telomeres, which protect the chromosome ends, more closely resemble those in humans. The Telomouse model, developed by incorporating a genetic variation from a mouse species with naturally shorter telomeres, provides a valuable resource for in-depth aging and cancer research. This discovery promises to reveal new insights into the genetics of aging and may contribute to enhanced longevity and well-being.
Published Controlling organoids with light
(via sciencedaily.com) Original source Organoids help researchers understand biological processes in health and in disease. It is, however, difficult to influence the way in which they organize themselves into complex tissues. Now a group has found a new way to do so.
Published To navigate the world, we all shimmy like these electric fish
(via sciencedaily.com) Original source An electric knifefish shimmies in the water for the same reason a dog sniffs or a human glances around a new place -- to make sense of their surroundings. For the first time, scientists demonstrate that a wide range of organisms, even microbes, perform the same pattern of movements in order to sense the world.
Published Defect in fruit fly respiratory system may provide insights into human aortic aneurysms
(via sciencedaily.com) Original source A team of researchers has gained new insights into the respiratory system of fruit flies -- the so-called tracheal system -- which could be important for future research into aneurysms. Scientists carried out genetic, cell biological and biochemical studies on Drosophila embryos. They found that the cells in the fruit fly's tracheal system are connected to the extracellular matrix by the proteins Dumpy and Piopio.
Published Bacteria can enhance host insect's fertility with implications for disease control
(via sciencedaily.com) Original source New research reveals how the bacteria strain Wolbachia pipientis enhances the fertility of the insects it infects, an insight that could help scientists increase the populations of mosquitoes that do not carry human disease.
Published New study shows surprising effects of fire in North America's boreal forests
(via sciencedaily.com) Original source Using satellite images, researchers found that fires in North America's boreal forest may be changing the environment in ways that researchers didn't previously anticipate.
Published What do new moms and roaches have in common?
(via sciencedaily.com) Original source Researchers are studying the dramatic physical transformation that some insects undergo to give birth to live young. This includes suppressing their immune systems to accommodate babies, which is something some insects and people have in common. Understanding how these systems work can help improve treatments for fibromyalgia and other immune disorders. An international team of researchers has examined the complex structural and physiological changes that take place in Hawaii's beetle-mimic cockroaches, which give birth to live young.
Published Restoring the function of a human cell surface protein in yeast cells
(via sciencedaily.com) Original source Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced into yeast cells. To tackle this issue, researchers developed an innovative strategy to restore GPCR function in yeast cells by inducing random mutations. Their findings can help understand GPCRs better and could pave the way to therapeutic breakthroughs for many diseases.
Published Stolen genes allow parasitic control of behavior
(via sciencedaily.com) Original source A research team has discovered that parasites manipulate their hosts using stolen genes that they likely acquired through a phenomenon called horizontal gene transfer.
Published Soft optical fibers block pain while moving and stretching with the body
(via sciencedaily.com) Original source New soft, implantable fibers can deliver light to major nerves through the body. They are an experimental tool for scientists to explore the causes and potential treatments for peripheral nerve disorders in animal models.
Published New insights into the genetics of the common octopus: Genome at the chromosome level decoded
(via sciencedaily.com) Original source Octopuses are fascinating animals -- and serve as important model organisms in neuroscience, cognition research and developmental biology. To gain a deeper understanding of their biology and evolutionary history, validated data on the composition of their genome is needed, which has been lacking until now. Scientists have now been able to close this gap and, in a new study, determined impressive figures: 2.8 billion base pairs -- organized in 30 chromosomes. What sounds so simple is the result of complex, computer-assisted genome analyses and comparisons with the genomes of other cephalopod species.
Published Unlocking the secrets of cell behavior on soft substrates: A paradigm shift in mechanobiology
(via sciencedaily.com) Original source A research group has developed a new method for studying how cancer cells function in softer and stiffer tissue environments. This insight challenges the existing paradigm, opening up new possibilities for research in cancer biology and tissue engineering.
Published Subalpine forests in the Northern Rockies are fire resilient--for now
(via sciencedaily.com) Original source Using lake sediment cores, scientists determined how these subalpine ecosystems recovered after 4,800 years of fire.