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Categories: Biology: Developmental, Environmental: Wildfires

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Researchers have discovered a strong immunological effect of the molecule LecB -- and a way to prevent it.

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A major new study reveals a 'traffic light' mechanism controlling genetic activity within cells -- a system which could potentially be targeted by cancer drugs already in development. The research describes how 'epigenetic' changes to the structure of DNA can act as a stop-go signal in determining whether a gene should be read. Unlike our genetic make-up, which is well understood, the world of epigenetics is still largely unexplored and referred to as the 'dark matter' of the genome.

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A detailed atlas of gene expression in the zebrafish brain.

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Leading environmental health experts have called for a comprehensive review of the UK's fire safety regulations, with a focus on the environmental and health risks of current chemical flame retardants.

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Textbooks will tell you that in dividing cells, production of new DNA peaks during the S-phase, while production of other macromolecules, such as proteins, lipids, and polysaccharides, continues at more or less the same level. Molecular biologists have now discovered that this is not true: protein synthesis shows two peaks and lipid synthesis peaks once.

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Haematopoietic stem cell transplantation for the treatment of severe blood cancers is the only medical intervention that has cured two people living with HIV in the past. An international group of physicians and researchers has now identified another case in which HIV infection has been shown to be cured in the same way. The successful healing process of this third patient was for the first time characterized in great detail virologically and immunologically over a time span of ten years.

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A team has developed a new software tool to help researchers across the life sciences more efficiently analyze animal behaviors.

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When scientists disabled a single regulatory gene in a species of sea anemone, a stinging cell that shoots a venomous miniature harpoon for hunting and self-defense shifted to shoot a sticky thread that entangles prey instead, according to a new study.

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Researchers created maps showing where warmer weather has left trees in conditions that don't suit them, making them more prone to being replaced by other species. The findings could help inform long-term wildfire and ecosystem management in these 'zombie forests.'

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Scientists transform blood cells to regain a flexible fate, growing into a precursor of sperm cells.

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Researchers have generated the first induced pluripotent stem cells (iPSCs) from bats, gaining valuable insights into the close relationship between bats and viruses.

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Researchers made the stunning discovery that telomeres contain genetic information to produce two small proteins, one of which they found is elevated in some human cancer cells, as well as cells from patients suffering from telomere-related defects.

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Using artificial intelligence (AI), researchers can now follow cell movement across time and space. The method could be very helpful for developing more effective cancer medications.

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Researchers have developed a machine learning-based ensemble approach to quantify fire-induced thaw settlement across the entire Tanana Flats in Alaska, which encompasses more than 3 million acres. They linked airborne repeat lidar data to time-series Landsat products (satellite images) to delineate thaw settlement patterns across six large fires that have occurred since 2000. The six fires resulted in a loss of nearly 99,000 acres of evergreen forest from 2000 to 2014 among nearly 155,000 acres of fire-influenced forests with varying degrees of burn severity. This novel approach helped to explain about 65 percent of the variance in lidar-detected elevation change.

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The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists have now found another molecular cause for this condition. The transcription factor MYT1L normally protects the molecular identity of nerve cells. If it is genetically switched off in human nerve cells or in mice, the functional changes and symptoms typical of autism occur. A drug that blocks sodium channels in the cell membrane can reverse the consequences of MYT1L failure and alleviate the functional and behavioral abnormalities in mice.

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Scientists have created a new technology to assemble matter in 3D. Their concept uses multiple acoustic holograms to generate pressure fields with which solid particles, gel beads and even biological cells can be printed. These results pave the way for novel 3D cell culture techniques with applications in biomedical engineering.

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Bee researchers have identified a new gene in honeybees, which is responsible for the dimorphic eye differentiation between males and females of the species. The researchers have now presented this gene and the evolutionary genetic conclusions they have drawn from it.

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In a new study, researchers discovered an unknown mechanism of how cells 'remember' their identity when they divide -- the cells' so-called epigenetic memory.

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Computer software can predict what happens to complex gene networks when individual genes are missing or dialed up more than usual. Mapping the roles of single genes in these networks is key to understanding healthy development and finding ways to regrow damaged cells and tissues. Understanding genetic errors could provide insight into birth defects, miscarriage or even cancer.

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Researchers show that brain organoids -- clumps of lab-grown neurons -- can integrate with rat brains and respond to visual stimulation like flashing lights.