Showing 20 articles starting at article 321
< Previous 20 articles Next 20 articles >
Categories: Biology: Developmental, Geoscience: Earthquakes
Published How animals get their stripes and spots



New research helps explain how sharp patterns form on zebras, leopards, tropical fish and other creatures. Their findings could inform the development of new high-tech materials and drugs.
Published Yeast with an over half synthetic genome is created in the lab



Researchers have combined over seven synthetic chromosomes that were made in the lab into a single yeast cell, resulting in a strain with more than 50% synthetic DNA that survives and replicates similarly to wild yeast strains. A global consortium is working to develop the first synthetic eukaryote genome from scratch. The team has now synthesized and debugged all sixteen yeast chromosomes.
Published Scientists take major step towards completing the world's first synthetic yeast



A team of Scientists has completed construction of a synthetic chromosome as part of a major international project to build the world's first synthetic yeast genome. The work represents completion of one of the 16 chromosomes of the yeast genome, which is part of the biggest project ever in synthetic biology; the international synthetic yeast genome collaboration. The collaboration, known as 'Sc2.0' has been a 15-year project involving teams from around the world (UK, US, China, Singapore, UK, France and Australia), working together to make synthetic versions of all of yeast's chromosomes. Alongside this paper, another 9 publications are also released today from other teams describing their synthetic chromosomes. The final completion of the genome project -- the largest synthetic genome ever -- is expected next year.
Published Obesity linked to neurodegeneration through insulin resistance



Researchers have discovered a link between obesity and neurodegenerative disorders like Alzheimer's disease. Using the common fruit fly, the research shows that a high-sugar diet -- a hallmark of obesity -- causes insulin resistance in the brain, which in turn reduces the ability to remove neuronal debris, thus increasing the risk of neurodegeneration.
Published New dates for landslides reveal past Seattle fault earthquakes



New maps of more than 1,000 deep-seated landslides in the Puget Lowlands of Washington State provide evidence of the last major earthquake along the Seattle Fault about 1,100 years ago -- and may also hold traces of older earthquakes along the fault.
Published Video technology could transform how scientists monitor changes in species evolution and development



New research combines microscope and video technology to analyze how different species develop, and how changes in the timings of any developments can be tracked. A detailed analysis of the Energy Proxy Traits (EPTs) that result from these processes has provided researchers with the first evidence that traditionally measured timings of developmental events are associated with far broader changes to the full set of an embryo's observable characteristics.
Published Research outlines how sex differences have evolved



Researchers have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.
Published Female sex determining gene identified in mice



Researchers have identified a gene which is an early determining factor of ovary development in mice.
Published A known environmental hazard can change the epigenetics of cells



An international team of researchers has discovered that formaldehyde, a widely spread pollutant and common metabolite in our body, interferes in the epigenetic programming of the cell. This finding expands the knowledge of formaldehyde, previously considered only as a DNA mutagen, and helps establishing a further link with cancer.
Published Immunology: Dysfunction of mitochondria drives the exhaustion of T cells



In the immune system's fight against cancer and infections, the T cells often lose their power. Now immunologists may have found a possible explanation for this phenomenon.
Published New study sheds light on the molecular mechanisms underlying lipid recycling within cells



Our understanding of how cells recycle lipids through autophagy -- a form of cellular degradation -- has grown significantly, thanks to a recent study. Using yeast as a model organism, the researchers explored the molecular mechanisms leading to the degradation of the phospholipid bilayers making up the cell membranes. Their findings improve our understanding of cellular degradation processes and related metabolic disorders.
Published Hebrew prayer book fills gap in Italian earthquake history



The chance discovery of a note written in a 15th century Hebrew prayer book fills an important gap in the historical Italian earthquake record, offering a brief glimpse of a previously unknown earthquake affecting the Marche region in the central Apennines.
Published First mice engineered to survive COVID-19 like young, healthy humans



Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a new study.
Published Where is a sea star's head? Maybe just about everywhere



A new study that combines genetic and molecular techniques helps solve the riddle of sea star (commonly called starfish) body plans, and how sea stars start life with bilateral body symmetry -- just like humans -- but grow up to be adults with fivefold 'pentaradial' symmetry.
Published The remains of an ancient planet lie deep within Earth



The remnants of an ancient planet that collided with Earth to form the Moon lie deep within the earth, according to a new model.
Published Pinpointing HIV immune response



New research combining computer modeling and experiments with macaques shows the body's immune system helps control human immunodeficiency virus (HIV) infections largely by suppressing viral production in already infected cells while also killing viral infected cells, but only within a narrow time window at the start of a cell's infection.
Published Maternal microbiota can affect fetal development



Significant differences in the gene activity of the fetal intestine, brain and placenta were identified, depending on the microbes in the mother's body and the compounds produced by them. The findings indicate that maternal microbes are important to her offspring's development and health.
Published New Nijmegen method reveals hidden genetic variations



Many hidden genetic variations can be detected with Chameleolyser, a new method. The information is already yielding new patient diagnoses and may also lead to the discovery of as yet unknown disease genes.
Published Advanced assisted reproduction in white rhinos is safe and reliable, shows evaluation of procedures



The BioRescue project develops and pioneers advanced assisted reproduction technologies (aART) for conservation in the face of the imminent extinction of most rhino species and subspecies. In a new scientific analysis, the team evaluated 65 aART procedures conducted from 2015 to 2022. The evaluation showed that aART is safe for the donor females with no detrimental health effects, and successful in that it yielded 51 embryos.
Published Scientists create special 'telomouse' with human-like telomeres



Researchers introduce the 'Telomouse'. By making a subtle genetic alteration in standard lab mice, they've made the mouse telomeres, which protect the chromosome ends, more closely resemble those in humans. The Telomouse model, developed by incorporating a genetic variation from a mouse species with naturally shorter telomeres, provides a valuable resource for in-depth aging and cancer research. This discovery promises to reveal new insights into the genetics of aging and may contribute to enhanced longevity and well-being.