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Categories: Biology: Developmental, Geoscience: Earthquakes

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Organoids help researchers understand biological processes in health and in disease. It is, however, difficult to influence the way in which they organize themselves into complex tissues. Now a group has found a new way to do so.

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An electric knifefish shimmies in the water for the same reason a dog sniffs or a human glances around a new place -- to make sense of their surroundings. For the first time, scientists demonstrate that a wide range of organisms, even microbes, perform the same pattern of movements in order to sense the world.

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A team of researchers has gained new insights into the respiratory system of fruit flies -- the so-called tracheal system -- which could be important for future research into aneurysms. Scientists carried out genetic, cell biological and biochemical studies on Drosophila embryos. They found that the cells in the fruit fly's tracheal system are connected to the extracellular matrix by the proteins Dumpy and Piopio.

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New research reveals how the bacteria strain Wolbachia pipientis enhances the fertility of the insects it infects, an insight that could help scientists increase the populations of mosquitoes that do not carry human disease.

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Researchers are studying the dramatic physical transformation that some insects undergo to give birth to live young. This includes suppressing their immune systems to accommodate babies, which is something some insects and people have in common. Understanding how these systems work can help improve treatments for fibromyalgia and other immune disorders. An international team of researchers has examined the complex structural and physiological changes that take place in Hawaii's beetle-mimic cockroaches, which give birth to live young.

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Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced into yeast cells. To tackle this issue, researchers developed an innovative strategy to restore GPCR function in yeast cells by inducing random mutations. Their findings can help understand GPCRs better and could pave the way to therapeutic breakthroughs for many diseases.

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A research team has discovered that parasites manipulate their hosts using stolen genes that they likely acquired through a phenomenon called horizontal gene transfer.

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New soft, implantable fibers can deliver light to major nerves through the body. They are an experimental tool for scientists to explore the causes and potential treatments for peripheral nerve disorders in animal models.

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New high-resolution images of the Long Valley Caldera indicate that the subsurface environment is cooling off, releasing gas and fluids that contribute to seismic activity.

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Octopuses are fascinating animals -- and serve as important model organisms in neuroscience, cognition research and developmental biology. To gain a deeper understanding of their biology and evolutionary history, validated data on the composition of their genome is needed, which has been lacking until now. Scientists have now been able to close this gap and, in a new study, determined impressive figures: 2.8 billion base pairs -- organized in 30 chromosomes. What sounds so simple is the result of complex, computer-assisted genome analyses and comparisons with the genomes of other cephalopod species.

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A research group has developed a new method for studying how cancer cells function in softer and stiffer tissue environments. This insight challenges the existing paradigm, opening up new possibilities for research in cancer biology and tissue engineering.

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One of the biggest challenges for earthquake early warning systems (EEW) is the lack of seismic stations located offshore of heavily populated coastlines, where some of the world's most seismically active regions are located. In a new study, researchers show how unused telecommunications fiber optic cable can be transformed for offshore EEW.

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A group of international scientists have mapped the genetic, cellular, and structural makeup of the human brain and the nonhuman primate brain. This understanding of brain structure allows for a deeper knowledge of the cellular basis of brain function and dysfunction, helping pave the way for a new generation of precision therapeutics for people with mental disorders and other disorders of the brain.

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Geologists have reconstructed a massive and previously unknown tectonic plate that was once one-quarter the size of the Pacific Ocean. The team had predicted its existence over 10 years ago based on fragments of old tectonic plates found deep in the Earth’s mantle. To the lead researchers surprise, she found that oceanic remnants on northern Borneo must have belonged to the long-suspected plate, which scientists have named Pontus. She has now reconstructed the entire plate in its full glory.

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Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics. The genome of a protist has revealed a seemingly unique divergence in the DNA code signalling the end of a gene, suggesting the need for further research to better understand this group of diverse organisms.  

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A new attempt to predict earthquakes has raised hopes that artificial intelligence could one day be used to limit earthquakes’ impact on lives and economies. The AI algorithm correctly predicted 70% of earthquakes a week before they happened during a seven-month trial in China. The system is limited because the AI needs an extensive database and years of seismic recordings to train itself on, but researchers said the effort is nonetheless a milestone for AI-driven earthquake forecasting. Researchers will soon begin testing the system at other locations.

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Researchers have developed a new open-source computational method, dubbed Spectra, which improves the analysis of single-cell transcriptomic data. By guiding data analysis in a unique way, Spectra can offer new insights into the complex interplay between cells — like the interactions between cancer cells and immune cells, which are critical to improving immunotherapy treatments.

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Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study.

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Researchers working to image New Zealand's Hikurangi earthquake fault have uncovered a sea's worth of water buried in the Earth's crust. The water was carried down by eroding volcanic rocks and is believed to be dampening the earthquake fault, allowing it to release most of the pent-up tectonic stress through harmless slow slip earthquakes.

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Researchers have produced an engineered tissue representing a simplified cerebral cortex by 3D printing human stem cells. When implanted into mouse brain slices, the structures became integrated with the host tissue. The technique may ultimately be developed into tailored repairs to treat brain injuries.