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Categories: Biology: Developmental, Geoscience: Earthquakes

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Researchers have developed a biosynthetic 'clock' that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.

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What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard. The new findings, published April 28 in the journal Science, fill an important gap in what is known about historical changes to the human genome.

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Even though it is important to know where these variations are located in the genome, it's also useful to know how or why these genetic variations happened in the first place.

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Scientists found parallels between the neural circuitry that guides locomotion in sea slugs and in more complex animals like mammals.

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Researchers develop an early warning system that combines acoustic technology with AI to immediately classify earthquakes and determine potential tsunami risk. They propose using underwater microphones, called hydrophones, to measure the acoustic radiation produced by the earthquake, which carries information about the tectonic event and travels significantly faster than tsunami waves. The computational model triangulates the source of the earthquake and AI algorithms classify its slip type and magnitude. It then calculates important properties like effective length and width, uplift speed, and duration, which dictate the size of the tsunami.

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The study is the first to identify a damage response pathway that is distinct from but parallel to the classical pathway triggered by pathogens.

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By studying green algae in Swedish lakes, a research team has succeeded in identifying which environmental conditions promote multicellularity. The results give us new clues to the amazing paths of evolution.

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Faults in the Ridgecrest, California area were very sensitive to solid earth tidal stresses in the year and a half before the July 2019 Ridgecrest earthquake sequence.

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Tsunami deposits identified in a coastal mangrove pond in Northwest Puerto Rico could have come from a megathrust earthquake at the Puerto Rico Trench that occurred between 1470 and 1530, according to new research.

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An essential pillar of Earth's ecological system, fungi have long been used to better the lives of humans. While these organisms are still vastly understudied, a new review paper suggests that their unique genomes could be used to make progress in the biotech industry.

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Investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.

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Using remote sensing, geophysicists have documented the massive Feb. 6 quake that killed more than 50,000 people in Eastern Turkey and toppled more than 100,000 buildings. Alarmingly, researchers found that a section of the fault remains unbroken and locked -- a sign that the plates there may, when friction intensifies, generate another magnitude 6.8 earthquake when it finally gives way.

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Even though most of the economic losses are concentrated in California and along the West Coast due to that region's high seismic hazard levels, significant population, and building exposure, earthquake risk is spread throughout the country. For example, there is a combined $3.1 billion per year in projected losses across the central U.S., Rocky Mountain region, Alaska, Hawaii, Puerto Rico and the Virgin Islands.

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Earthquakes and volcanism occur as a result of plate tectonics. The movement of tectonic plates themselves is largely driven by the process known as subduction. The question of how new active subduction zones come into being, however, is still under debate. An example of this is the volcanic Lesser Antilles arc in the Caribbean. A research team recently developed models that simulated the occurrences in the Caribbean region during the Cretaceous, when a subduction event in the Eastern Pacific led to the formation of a new subduction zone in the Atlantic. The computer simulations show how the collision of the old Caribbean plateau with the Greater Antilles arc contributed to the creation of this new Atlantic subduction zone. Some 86 million years ago, the triggered processes subsequently resulted in a major mantle flow and thus to the development of the Caribbean large igneous province.

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Certain stem cells have a unique ability to move between growth compartments in hair follicles, but get stuck as people age and so lose their ability to mature and maintain hair color, a new study shows.

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Two protein complexes carry the major responsibility for the spatial organization of chromosomes in our cell nuclei. DNA tension plays a surprising role in this. Nanoscientists now publish how they have visualized this.

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A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.

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A research team has recently made a significant discovery about the evolutionary age of different type of cells in a small animal called Caenorhabditis elegans (C. elegans). By using single-cell transcriptomic data and refined phylostratigraphy, the team determines the transcriptomic age of individual cells, which means they are able to estimate the evolutionary origin of different cells based on the age of the genes expressed in the cells.

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Genes are not the only drivers of evolution. The iconic fins of skates are caused by changes in the non-coding genome and its three-dimensional structure, an international research team reports.

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Acylceramides and protein-bound ceramides are vital for the formation of the oral barrier in mice, similar to their role in skin, protecting from infection.