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Categories: Biology: Developmental, Geoscience: Geography

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Discover the first images of cytonemes during mammalian neural development, serving as express routes to establish morphogen gradients and tissue patterning.

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Scientists use a 3km high-resolution climate model to reveal expanded extreme rainfall from typhoons.

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Tiny things matter -- for instance, one amino acid can completely alter the architecture of the cell. Researchers have now investigated the structure and mechanics of the main component of the cytoskeleton of the cell: a protein known as actin. Actin is found in all living cells where it has a range of important functions -- from muscle contraction to cell signalling and cell shape. This protein comes in two different varieties termed 'isoforms', which are known as gamma actin and beta actin.

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At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days -- but how? Regenerating functional tissue across species, including salamanders and insects, relies on the ability to form a blastema, a clump of undifferentiated cells that can repair damage and grow into the missing appendage. Jellyfish, along with other cnidarians such as corals and sea anemones, exhibit high regeneration abilities, but how they form the critical blastema has remained a mystery until now.

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A new methodology that allows for the categorization and organization of single-cell data has been launched. It can be used to create a harmonized dataset for the study of human health and disease.

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Scientists have developed an efficient, non-invasive, and pain-free method to generate canine-induced pluripotent stem cells (iPSCs). They identified six reprogramming genes that can boost canine iPSC generation by 120 times compared to conventional methods using fibroblasts. The iPSCs were created from urine-derived cells without the need for feeder cells, an impossible feat until now. Their findings are expected to advance regenerative medicine and genetic disease research in veterinary medicine.

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How do national policies impact deforestation? Researchers have looked into this question at the global scale and have found that, contrary to common assumptions, national strategies have a significant -- and visible -- influence on efforts to protect forest heritage.

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A research group found that in female fruit flies, microorganisms enhance reproductive function, boosting the number of cells that form eggs and the number of mature eggs. This is done by controlling the release of hormones to speed up cell division in the ovaries, and limiting programmed cell death. These findings could improve reproductive medicine and could aid the development of new methods to enhance fertility.

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Scientists have uncovered how DnaA, the master key to DNA replication, opens the door to bacterial growth. This breakthroughpaves the way for new antibiotics to combat the rising tide of antibiotic resistance.

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Researchers have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.

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A new technique to clone and reassemble DNA, dubbed CReATiNG, could simplify and lower the cost to make synthetic chromosomes. Potential applications are numerous, including pharmaceutical production, biofuel generation, cancer therapies, and environmental cleanup using modified organisms. The method adds a powerful, versatile tool to the burgeoning field of synthetic biology.

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The world's ocean are a vast habitat for countless creatures that settle, spawn, dig or feed on the seafloor. They also influence the shape of the ocean floor. How exactly this takes place has been scarcely investigated so far. In an interdisciplinary study, geoscientists, biologists and oceanographers, have examined crater-like depressions on the seafloor of the North Sea. They were able to show that these directly relate to the habitats of porpoises and sand eels, and for the first time provide a conclusive explanation for the importance of vertebrates in shaping the seafloor.

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A research team has uncovered a previously undetected mechanism in mice -- starring the genetic molecule RNA -- that could explain how each sensory cell, or neuron, in mammalian noses becomes tailored to detect a specific odor chemical.

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The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time. Scientists have recently uncovered a fascinating aspect of this process known as 'replication timing' (RT) and how special this is when life commences.

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Scientists outline the first direct evidence linking seemingly random weather systems in the ocean with climate on a global scale. The team's work creates a promising framework for better understanding the climate system.

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Reducing air pollution to levels similar to those during the coronavirus pandemic could protect the glaciers in the Himalayas and prevent them from disappearing by the end of the century. This is the conclusion reached by an international research team analyzing the situation during the COVID-19 lockdown in 2020.

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Nearly every organism on Earth follows a natural circadian rhythm that is coded by your cell's clock genes, which do exactly as you suspect from the name: regulate your body's rhythm on a 24-hour basis. Most cells in mammalian bodies have cilia of some sort, which are hair-like structures that perform a variety of functions such as movement for motile cilia and aiding in structure in function for non-motile, or primary, cilia. The primary cilia also act as a sensory organ for the cell, a function which has illuminated the primary cilia's potential role in the healing process and how bodies heal at a different rate according to our circadian rhythm. In this research, the role of the primary cilia, biological clock and wound healing is explored.

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Almost all eukaryotic organisms, from plants and animals to fungi, can't survive without mitochondria -- the 'powerhouses of the cell,' which generate chemical energy using oxygen. However, a new study finds that multiple members of the oxymonads, a group of single-celled protists that live inside the guts of termites and other animals, have evolved to live quite happily without them.

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Researchers report that local rivers and streams were the source of the Salmonella enterica contamination along coastal North Carolina after Hurricane Florence in 2018 -- not the previously suspected high number of pig farms in the region.

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Our understanding of which aquatic species produce sounds just took a big step forward. Scientists have created an inventory of species confirmed or expected to produce sound underwater.