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Categories: Biology: Developmental, Geoscience: Geography
Published Keeping an eye on the regions when it comes to climate change



Up to now, the results of climate simulations have sometimes contradicted the analysis of climate traces from the past. Physicists and climatologists have now brought together experts in climate models and climate tracks to clarify how the discrepancies come about. The surprising result has now been published: in a way, both sides are right. Climate models correctly simulate global temperature trends, but often underestimate the strength of regional climate fluctuations, especially over the course of decades to centuries.
Published How salt from the Caribbean affects our climate



Past cold periods such as the Little Ice Age were associated with reduced strength of North Atlantic currents and increased surface salinity in the Caribbean. This was accompanied by disturbances in the distribution of salt to the north leading to longer, stronger cooling phases in the northern hemisphere.
Published Scientists map loss of groundwater storage around the world



Global water resources are stretched by climate change and human population growth, and farms and cities are increasingly turning to groundwater to fill their needs. Unfortunately, the pumping of groundwater can cause the ground surface above to sink, as the aquifers below are drained and the architecture of the ground collapses. A new study maps this loss of groundwater storage capacity around the world.
Published Large herbivores such as elephants, bison and moose contribute to tree diversity



Using global satellite data, a research team has mapped the tree cover of the world's protected areas. The study shows that regions with abundant large herbivores in many settings have a more variable tree cover, which is expected to benefit biodiversity overall.
Published Predicting saltwater intrusion into groundwater using Plymouth, Mass. as test case



As the world warms and ice sheets melt, the ocean continually rises. The greater Boston area can expect to see between one and six feet of sea level rise by 2100, according to recent estimates. To find out what this rise might mean for freshwater supplies, a team of hydrogeologists developed an innovative new model that can not only predict saltwater intrusion over the next 75 years, but also pinpoint the main sources of salt contamination today -- road salt and human development.
Published Research outlines how sex differences have evolved



Researchers have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.
Published Female sex determining gene identified in mice



Researchers have identified a gene which is an early determining factor of ovary development in mice.
Published A known environmental hazard can change the epigenetics of cells



An international team of researchers has discovered that formaldehyde, a widely spread pollutant and common metabolite in our body, interferes in the epigenetic programming of the cell. This finding expands the knowledge of formaldehyde, previously considered only as a DNA mutagen, and helps establishing a further link with cancer.
Published Immunology: Dysfunction of mitochondria drives the exhaustion of T cells



In the immune system's fight against cancer and infections, the T cells often lose their power. Now immunologists may have found a possible explanation for this phenomenon.
Published How a climate model can illustrate and explain ice-age climate variability



During the last ice age, the last glacial maximum about 20,000 years ago, the climate in the North Atlantic underwent much greater multi-centennial variability than it does in the present warm period. This is supported by evidence found in ice and seafloor cores. Researchers have now shown, based on a climate model, that internal mechanisms such as temperature and salinity distribution in the ocean are driving this multi-centennial variability.
Published New study sheds light on the molecular mechanisms underlying lipid recycling within cells



Our understanding of how cells recycle lipids through autophagy -- a form of cellular degradation -- has grown significantly, thanks to a recent study. Using yeast as a model organism, the researchers explored the molecular mechanisms leading to the degradation of the phospholipid bilayers making up the cell membranes. Their findings improve our understanding of cellular degradation processes and related metabolic disorders.
Published Study links changes in global water cycle to higher temperatures



A new study takes an important step toward reconstructing a global history of water over the past 2,000 years. Using geologic and biologic evidence preserved in natural archives -- including 759 different paleoclimate records from globally distributed corals, trees, ice, cave formations and sediments -- the researchers showed that the global water cycle has changed during periods of higher and lower temperatures in the recent past.
Published First mice engineered to survive COVID-19 like young, healthy humans



Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a new study.
Published Where is a sea star's head? Maybe just about everywhere



A new study that combines genetic and molecular techniques helps solve the riddle of sea star (commonly called starfish) body plans, and how sea stars start life with bilateral body symmetry -- just like humans -- but grow up to be adults with fivefold 'pentaradial' symmetry.
Published The ringed seals in Ilulissat Icefjord, Greenland are special



Local hunters in the Icefjord near Ilulissat have long known about a special ringed seal -- the Kangia seal -- which is significantly larger and has a markedly different fur color and pattern than typical Arctic ringed seals. Now scientific studies have shown that the Kangia ringed seal has been isolated from other ringed seals for a long period of time -- more than 100,000 years.
Published Pinpointing HIV immune response



New research combining computer modeling and experiments with macaques shows the body's immune system helps control human immunodeficiency virus (HIV) infections largely by suppressing viral production in already infected cells while also killing viral infected cells, but only within a narrow time window at the start of a cell's infection.
Published Ocean warming is accelerating, and hotspots reveal which areas are absorbing the most heat



A new study reveals increasing warming rates in the world's oceans in recent decades and the locations with the greatest heat uptake.
Published Maternal microbiota can affect fetal development



Significant differences in the gene activity of the fetal intestine, brain and placenta were identified, depending on the microbes in the mother's body and the compounds produced by them. The findings indicate that maternal microbes are important to her offspring's development and health.
Published New Nijmegen method reveals hidden genetic variations



Many hidden genetic variations can be detected with Chameleolyser, a new method. The information is already yielding new patient diagnoses and may also lead to the discovery of as yet unknown disease genes.
Published A mathematical model for studying methane hydrate distribution in the Nankai Trough



Naturally occurring methane hydrate deposits are potential sources of energy. However, their observation in natural environments remains challenging. Researchers have now developed a one-dimensional mathematical flow model to indirectly observe the formation and accumulation of methane hydrates under different lithological and fluid conditions in the Nankai Trough of Japan. Numerical simulations using this model revealed important insights that could help in the extraction of methane hydrates and the prevention of geohazards in the future.