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Categories: Biology: Developmental, Geoscience: Geochemistry
Published Sweet move: a modified sugar enhances antisense oligonucleotide safety and efficacy
(via sciencedaily.com) Original source Researchers found that adding a newly developed modified sugar, BNAP-AEO, to gapmer antisense oligonucleotides (ASOs) increased their affinity for target RNAs, thus significantly enhancing their gene-silencing effects in vitro and in vivo. The BNAP-AEO modification also decreased gapmer ASO toxicity to the central nervous system (CNS), suggesting that it could improve the clinical application of ASO treatment of CNS disease.
Published How the 'home' environment influences microbial interactions
(via sciencedaily.com) Original source A new study shows that real-world ocean conditions make a huge difference in how viral infection affects host bacteria. The findings indicate it is very important to study cells and virocells under nutrient conditions that more closely resemble what they encounter in nature.
Published Promethium bound: Rare earth element's secrets exposed
(via sciencedaily.com) Original source Scientists have uncovered the properties of a rare earth element that was first discovered 80 years ago at the very same laboratory, opening a new pathway for the exploration of elements critical in modern technology, from medicine to space travel.
Published New AI accurately predicts fly behavior
(via sciencedaily.com) Original source Researchers trained an AI model to accurately predict male fruit flies' courtship behavior in response to any sight of a female. This breakthrough offers new insight into how the brain processes visual data and may someday pave the way for artificial vision technology.
Published 'Fossilizing' cracks in infrastructure creates sealing that can even survive earthquakes
(via sciencedaily.com) Original source In a new study, a team of researchers used research on fossilizing techniques to create a new method for sealing cracks and fractures in rocks and bedrock using a 'concretion-forming resin'. This innovative technique has applications in a wide range of industries, from tunnel construction to long-term underground storage of hazardous materials.
Published New polystyrene recycling process could be world's first to be both economical and energy-efficient
(via sciencedaily.com) Original source Engineers have modeled a new way to recycle polystyrene that could become the first viable way of making the material reusable.
Published New insights into the degradation dynamics of organic material in the seafloor
(via sciencedaily.com) Original source Many processes in the deep sea are not yet well understood, and the role of microbial communities in particular is often a big unknown. This includes, for example, how organic material that sinks from the water surface to the ocean floor is metabolised -- an important building block for a better understanding of the global carbon cycle.
Published Study finds widespread 'cell cannibalism,' related phenomena across tree of life
(via sciencedaily.com) Original source Researchers describe cell-in-cell phenomena in which one cell engulfs and sometimes consumes another. The study shows that cases of this behavior, including cell cannibalism, are widespread across the tree of life. The findings challenge the common perception that cell-in-cell events are largely restricted to cancer cells. Rather, these events appear to be common across diverse organisms, from single-celled amoebas to complex multicellular animals.
Published Alaska's rusting waters: Pristine rivers and streams turning orange
(via sciencedaily.com) Original source Dozens of Alaska's rivers and streams are turning orange. The staining could be the result of minerals exposed by thawing permafrost and climate change, finds a new study.
Published Researchers find unique adaptations of fungus associated with bee bread
(via sciencedaily.com) Original source The past attempts of honey bee researchers to inventory the fungal diversity in honey bee colonies revealed that Aspergillus flavus is frequently found in hives. In a new study, researchers have discovered that this fungus is uniquely adapted to survive in bee colonies.
Published Studies reveal cell-by-cell changes caused when pig hearts and kidneys are transplanted into humans
(via sciencedaily.com) Original source Two new studies detail the changes seen at the single-cell level in pig organs and recipient human bodies before, during, and just after the xenotransplantation surgeries in the decedents.
Published Can coal mines be tapped for rare earth elements?
(via sciencedaily.com) Original source A team of geologists analyzed 3,500 samples taken in and around coal mines in Utah and Colorado. Their findings open the possibility that these mines could see a secondary resource stream in the form of rare earth metals used in renewable energy and numerous other high-tech applications.
Published Unraveling the drought dilemma: Can reservoirs be a carbon source?
(via sciencedaily.com) Original source A team delves into the spatiotemporal patterns of water volume and total organic carbon concentration of agricultural reservoirs.
Published Diverse headgear in hoofed mammals evolved from common ancestor
(via sciencedaily.com) Original source From the small ossicones on a giraffe to the gigantic antlers of a male moose -- which can grow as wide as a car -- the headgear of ruminant hooved mammals is extremely diverse, and new research suggests that despite the physical differences, fundamental aspects of these bony adaptations likely evolved from a common ancestor.
Published New mechanisms behind antibiotic resistance
(via sciencedaily.com) Original source Two newly discovered mechanisms in bacteria have been identified that can contribute to the development of antibiotic resistance. Changing the number of copies of resistance genes in bacteria increases antibiotic resistance, and can do so very quickly. These two mechanisms, along with a third known mechanism, can occur independently of each other, even within the same bacterial cell.
Published Extreme complexity in formation of rare earth mineral vital for tech industry
(via sciencedaily.com) Original source Researchers have unveiled that myriad, intricate factors influence the genesis and chemistry of bastnasite and rare earth carbonates, which are critically needed for today's tech industry and its hardware outputs. Their work unveils a newly acquired depth of understanding that had previously been unexplored in this field. In combination, the findings mark a significant advancement and promise to reshape our understanding of rare earth mineral formation.
Published Scientists develop new geochemical 'fingerprint' to trace contaminants in fertilizer
(via sciencedaily.com) Original source An international team of scientists has revealed high levels of toxic metals in global phosphate fertilizers using a isotopic variants of the element strontium as a tracer to uncover metals in soil, groundwater and possibly the food chain.
Published Chronic wasting disease unlikely to move from animals to people
(via sciencedaily.com) Original source A new study of prion diseases, using a human cerebral organoid model, suggests there is a substantial species barrier preventing transmission of chronic wasting disease (CWD) from cervids -- deer, elk and moose -- to people. The findings are consistent with decades of similar research in animal models.
Published Can we revolutionize the chemical industry and create a circular economy? Yes, with the help of catalysts
(via sciencedaily.com) Original source A new commentary paper puts forth a transformative solution to the unsustainable reliance on fossil resources by the chemical industry: catalysis to leverage sustainable waste resources, ushering the industry from a linear to a circular economy.
Published Zombie cells in the sea: Viruses keep the most common marine bacteria in check
(via sciencedaily.com) Original source Marine microbes control the flux of matter and energy essential for life in the oceans. Among them, the bacterial group SAR11 accounts for about a third of all the bacteria found in surface ocean waters. A study now reveals that at times nearly 20% of SAR11 cells are infected by viruses, significantly reducing total cell numbers. The viruses can also transform these once thriving bacteria into zombies, a phenomenon observed for the first time and widespread in the oceans.