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Categories: Biology: Developmental, Space: Exploration

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Discover the first images of cytonemes during mammalian neural development, serving as express routes to establish morphogen gradients and tissue patterning.

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Imagine blasting off on a multiyear voyage to Mars, fueled by a diet of bland, prepackaged meals. As space agencies plan for longer missions, they're grappling with the challenge of how to best feed people. Now, researchers have designed the optimal 'space meal': a tasty vegetarian salad. They chose fresh ingredients that meet male astronauts' specialized nutritional needs and can be grown in space.

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Best chance of finding liquid water, and even life on other planets, is to look for the absence of carbon dioxide in their atmospheres.

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Tiny things matter -- for instance, one amino acid can completely alter the architecture of the cell. Researchers have now investigated the structure and mechanics of the main component of the cytoskeleton of the cell: a protein known as actin. Actin is found in all living cells where it has a range of important functions -- from muscle contraction to cell signalling and cell shape. This protein comes in two different varieties termed 'isoforms', which are known as gamma actin and beta actin.

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At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days -- but how? Regenerating functional tissue across species, including salamanders and insects, relies on the ability to form a blastema, a clump of undifferentiated cells that can repair damage and grow into the missing appendage. Jellyfish, along with other cnidarians such as corals and sea anemones, exhibit high regeneration abilities, but how they form the critical blastema has remained a mystery until now.

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Analysis of organic compounds -- called polycyclic aromatic hydrocarbons (PAHs) -- extracted from the Ryugu asteroid and Murchison meteorite has found that certain PAHs likely formed in the cold areas of space between stars rather than in hot regions near stars as was previously thought. The findings open new possibilities for studying life beyond Earth and the chemistry of objects in space.

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 A new snapshot of an ancient, far-off galaxy could help scientists understand how it formed and the origins of our own Milky Way.   At more than 12 billion years old, BRI 1335-0417 is the oldest and furthest known spiral galaxy in our universe. The researchers were able to not only capture the motion of the gas around BRI 1335-0417, but also reveal a seismic wave forming -- a first in this type of early galaxy.  

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While many holiday traditions involve feasts of turkey, soba noodles, latkes or Pan de Pascua, this year, the European Southern Observatory is bringing you a holiday chicken. The so-called Running Chicken Nebula, home to young stars in the making, is revealed in spectacular detail in this 1.5-billion-pixel image captured by the VLT Survey Telescope.

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A new photo of Saturn was taken by NASA's Hubble Space Telescope on October 22, 2023, when the ringed planet was approximately 850 million miles from Earth. Hubble's ultra-sharp vision reveals a phenomenon called ring spokes.

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In November 2023, NASA's James Webb Space Telescope observed a massive cluster of galaxies named MACS J0138.0-2155. Through an effect called gravitational lensing, first predicted by Albert Einstein, a distant galaxy named MRG-M0138 appears warped by the powerful gravity of the intervening galaxy cluster. In addition to warping and magnifying the distant galaxy, the gravitational lensing effect caused by MACS J0138 produces five different images of MRG-M0138.

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A new methodology that allows for the categorization and organization of single-cell data has been launched. It can be used to create a harmonized dataset for the study of human health and disease.

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Scientists have developed an efficient, non-invasive, and pain-free method to generate canine-induced pluripotent stem cells (iPSCs). They identified six reprogramming genes that can boost canine iPSC generation by 120 times compared to conventional methods using fibroblasts. The iPSCs were created from urine-derived cells without the need for feeder cells, an impossible feat until now. Their findings are expected to advance regenerative medicine and genetic disease research in veterinary medicine.

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A pancake stack of radioactivity-sensitive films carried through the sky by a balloon was able to take the world's most accurate picture of a neutron star's gamma ray beam. To achieve this, researchers combined the oldest method of capturing radioactive radiation with the newest data capturing techniques and a clever time-recording device.

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A research group found that in female fruit flies, microorganisms enhance reproductive function, boosting the number of cells that form eggs and the number of mature eggs. This is done by controlling the release of hormones to speed up cell division in the ovaries, and limiting programmed cell death. These findings could improve reproductive medicine and could aid the development of new methods to enhance fertility.

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Scientists have uncovered how DnaA, the master key to DNA replication, opens the door to bacterial growth. This breakthroughpaves the way for new antibiotics to combat the rising tide of antibiotic resistance.

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Researchers have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.

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A new technique to clone and reassemble DNA, dubbed CReATiNG, could simplify and lower the cost to make synthetic chromosomes. Potential applications are numerous, including pharmaceutical production, biofuel generation, cancer therapies, and environmental cleanup using modified organisms. The method adds a powerful, versatile tool to the burgeoning field of synthetic biology.

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A research team has uncovered a previously undetected mechanism in mice -- starring the genetic molecule RNA -- that could explain how each sensory cell, or neuron, in mammalian noses becomes tailored to detect a specific odor chemical.

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The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time. Scientists have recently uncovered a fascinating aspect of this process known as 'replication timing' (RT) and how special this is when life commences.

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Researchers have discovered the transformative potential of Martian nanomaterials, potentially opening the door to sustainable habitation on the red planet.