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Categories: Biology: Developmental, Space: Exploration

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The supermassive black hole at the heart of galaxy M87, made famous by the first picture of a black hole shadow, has yielded another first: the jet shooting out from the black hole has been confirmed to wobble, providing direct proof that the black hole is spinning.

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Experts in cloning and stem cell science are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis, and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.

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A new study of the intriguing TRAPPIST-1 exoplanetary system has demonstrated the complex interaction between the activity of the system's star and its planetary features.

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Scientists have discovered a simple and reliable test for signs of past or present life on other planets -- 'the holy grail of astrobiology.' Researchers report that, with 90% accuracy, their artificial intelligence-based method distinguished modern and ancient biological samples from those of abiotic origin.

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Even without a central brain, jellyfish can learn from past experiences like humans, mice, and flies, scientists report for the first time. They trained Caribbean box jellyfish (Tripedalia cystophora) to learn to spot and dodge obstacles. The study challenges previous notions that advanced learning requires a centralized brain and sheds light on the evolutionary roots of learning and memory.

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With the launch of the James Webb Space Telescope, astronomers are now able to peer so far back in time that we are approaching the epoch where we think that the first galaxies were created. Throughout most of the history of the Universe, galaxies seemingly tend to follow a tight relation between how many stars they have formed, and how many heavy elements they have formed. But for the first time we now see signs that this relation between the amount of stars and elements does not hold for the earliest galaxies. The reason is likely that these galaxies simply are in the process of being created, and have not yet had the time to create the heavy elements.

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Galaxies from the early Universe are more like our own Milky Way than previously thought, flipping the entire narrative of how scientists think about structure formation in the Universe, according to new research.

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Astronomers using data from NASA's James Webb Space Telescope have identified carbon dioxide in a specific region on the icy surface of Europa.

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Researchers have developed the first method to uncover the tasks that microRNAs perform in single cells. This is a huge improvement over existing state-of-the-art methods that require millions of cells and will for the first time allow researchers to study microRNAs in complex tissues such as brains.

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In a new study in mice, researchers have uncovered a crucial component for restoring functional activity after spinal cord injury. The neuroscientists have shown that re-growing specific neurons back to their natural target regions led to recovery, while random regrowth was not effective.

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How do our muscles respond at the molecular level to exercise? Researchers have unraveled the cellular basis and signaling pathways responsible for the positive impact of physical activity on our overall health. Regulatory T cells, a type of immune cell, play a critical role in ensuring proper muscle function. These novel insights are paving the path towards precision medicines targeting metabolic disorders like obesity and diabetes, as well as muscle-related illnesses.

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The first use of a novel method of analyzing Mars' gravitational force supports the idea that the planet once had an extensive northern ocean. In doing so, the method defines the scope of what scientists refer to as the northern Martian paleo-ocean in more detail.

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Researchers have developed a method that lets them genetically modify each cell differently in animals. This allows them to study in a single experiment what used to require many animal experiments. Using the new method, the researchers have discovered genes that are relevant for a severe rare genetic disorder.

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An international research team has used the James Webb Space Telescope and the Atacama Large Millimeter/submillimeter Array to observe the most distant galaxy protocluster to date, 13.14 billion light-years away. The team has successfully captured the 'core region' of the galaxy protocluster, which corresponds to a metropolitan area with a particularly high number density of galaxies. The team has revealed that many galaxies are concentrated in a small area and that the growth of galaxies is accelerated. Furthermore, the team used simulations to predict the future of the metropolitan area and found that the region will merge into one larger galaxy within tens of millions of years. These results are expected to provide important clues regarding the birth and growth of galaxies.

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A new study sheds new light on the origins of modern brain cells. Researchers find evidence that specialized secretory cells found in placozoans, tiny sea creatures the size of a grain of sand, have many similarities to the neuron, such as the genes required to create a partial synapse. From an evolutionary point of view, early neurons might have started as something like these cells, eventually gaining the ability to create a complete synapse, form axons and dendrites and create ion channels that generate fast electrical signals -- innovations which gave rise to the neuron in more complex animals such as jellyfish. Though the complete story of how the first neuron appeared remains to be told, the study demonstrates that the basic building blocks for our brain cells were forming in the ancestors of placozoans grazing inconspicuously in the shallow seas of Earth around 800 million years ago.

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A team recently calculated that most of the Moon's permanently shadowed regions (PSRs) are at most around 3.4 billion years old and can contain relatively young deposits of water ice. Water resources are considered key for sustainable exploration of the Moon and beyond, but these findings suggest that current estimates for cold-trapped ices are too high.

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Mice treated aboard the International Space Station showed significantly reduced bone loss.

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Scientists have used data from the James Webb Space Telescope (JWST) as part of the Cosmic Evolution Early Release Science (CEERS) Survey to change the way we think about the universe and its distant galaxies. Astronomers authored a paper confirming very bright galaxies in the early universe, while also disproving the identification of what would have been the most distant galaxy ever found.

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Researchers have developed a novel genome editing technique known as NICER, which results in significantly fewer off-target mutations than CRISPR/Cas9 editing. The technique uses a different type of enzyme that makes single-stranded 'nicks' in the DNA. Repair of these nicks is more efficient and accurate than repair of double-strand breaks caused by the current CRISPR/Cas9 editing. This technique represents a novel approach for the treatment of genetic diseases caused by heterozygous mutations.

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Herbig-Haro (HH) objects are luminous regions surrounding newborn stars, formed when stellar winds or jets of gas spewing from these newborn stars form shock waves colliding with nearby gas and dust at high speeds. This image of HH 211 from NASA's James Webb Space Telescope reveals an outflow from a Class 0 protostar, an infantile analog of our Sun when it was no more than a few tens of thousands of years old and with a mass only 8% of the present-day Sun (it will eventually grow into a star like the Sun).