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Categories: Anthropology: Early Humans, Biology: Developmental

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In a step forward in the development of genetic medicines, researchers have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body. If translated into the clinic, this approach could expand access and reduce the cost of gene therapies for blood disorders, many of which currently require patients receive chemotherapy and a stem cell transplant.

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An international team of linguists and geneticists has achieved a significant breakthrough in our understanding of the origins of Indo-European, a family of languages spoken by nearly half of the world's population.

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What happens inside the carnivorous plant Venus Flytrap when it catches an insect? New technology has led to discoveries about the electrical signalling that causes the trap to snap shut. Bioelectronic technology enables advanced research into how plants react to their surroundings, and to stress.

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The lifespan of a small roundworm that has been used as a key model organism in aging research is limited by how it self-sacrifices to feed its young, finds a new study.

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The Neolithic burial site of Gurgy 'les Noisats' in France revealed two unprecedentedly large family trees which allowed a Franco-German team to explore the social organization of the 6,700-year-old community. Based on multiple lines of evidence, the team describes a close kin group which practiced monogamy and female exogamy, and experienced generally stable times.

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The results of a novel study has revealed exciting findings in the pursuit of an HIV cure.

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Researchers have identified a genetic sequence that is essential for plant reproduction. As this region is found in all plant species, it is expected to contribute to future crossbreeding initiatives and help solve the important problem of seed formation defects.

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The genetic changes that made it possible for humans to walk upright have been uncovered in a study that also shows how slight variations in skeletal proportions are linked to arthritis.

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Butterflies and moths share 'blocks' of DNA dating back more than 200 million years, new research shows.

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Researchers have identified the oldest decisive evidence of humans' close evolutionary relatives butchering and likely eating one another.

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Warmer temperatures are known to make more turtle eggs become female hatchlings, but new research shows that those females also have a higher capacity for egg production, even before their sex is set. This finding may explain why many animals besides turtles have temperature-dependent sex determination and why the system persists, despite seeming like a risky strategy. It may also provide a troubling glimpse of what could lie ahead in a warming world.

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An obscure aquatic plant has helped to explain how plants avoid cracking up under the stresses and strains of growth.

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Engineers designed a technology to probe connections between the brain and the digestive tract. Using fibers embedded with a variety of sensors, as well as optogenetic stimulation, the researchers could control neural circuits connecting the gut and the brain, in mice.

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Fifteen years of archaeological work in the Tam Pa Ling cave in northeastern Laos has yielded a reliable chronology of early human occupation of the site. The team's excavations through the layers of sediments and bones that gradually washed into the cave and were left untouched for tens of thousands of years reveals that humans lived in the area for at least 70,000 years -- and likely even longer.

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Researchers have outlined the structure and function of a protein complex which is required to repair damaged DNA and protect against cancer.

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Scientists have uncovered a new quality control system that removes damaged cells from early developing embryos.

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Researchers have used an unprecedented stem cell zoo to compare six different mammalian species and their developmental time.

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Research sheds light on human evolution, and demonstrates an approach for identifying significant differences in how genes are used between closely-related species.

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Genome Architecture Mapping captures complex, multi-way interactions in the genome. This is different than the workhorse technique of 3D genomics, which sees mostly two-way contacts, finds a new study.

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Scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations.