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Categories: Anthropology: Early Humans, Biology: Developmental
Published Biologists determine the evolutionary age of individual cell types providing critical insights for animal development
(via sciencedaily.com) Original source A research team has recently made a significant discovery about the evolutionary age of different type of cells in a small animal called Caenorhabditis elegans (C. elegans). By using single-cell transcriptomic data and refined phylostratigraphy, the team determines the transcriptomic age of individual cells, which means they are able to estimate the evolutionary origin of different cells based on the age of the genes expressed in the cells.
Published How skates learned to fly through water
(via sciencedaily.com) Original source Genes are not the only drivers of evolution. The iconic fins of skates are caused by changes in the non-coding genome and its three-dimensional structure, an international research team reports.
Published Oral barrier is similar in ceramide composition to skin barrier
(via sciencedaily.com) Original source Acylceramides and protein-bound ceramides are vital for the formation of the oral barrier in mice, similar to their role in skin, protecting from infection.
Published Genes are read faster and more sloppily in old age
(via sciencedaily.com) Original source Scientists have demonstrated the following findings which apply across the animal kingdom: with increasing age, the transcriptional elongation speed of genes increases, whereby the quality of the gene products suffers. With dietary restrictions, these processes could be reversed.
Published Stowaways in the genome
(via sciencedaily.com) Original source Scientists have discovered over 30,000 viruses by using the high-performance computer cluster 'Leo' and sophisticated detective work. The viruses hide in the DNA of unicellular organisms. In some cases, up to 10% of microbial DNA consists of built-in viruses.
Published Male yellow crazy ants are real-life chimeras
(via sciencedaily.com) Original source Researchers discovered that males of the yellow crazy ant have maternal and paternal genomes in different cells of their body and are thus chimeras.
Published Jellyfish and fruit flies shed light on the origin of hunger regulation
(via sciencedaily.com) Original source To survive, all organisms must regulate their appetite. Hormones and small proteins called neuropeptides perform this process, stimulating feelings of hunger and fullness. When researchers noted the similarities between GAWamide, a neuropeptide that regulates feeding in the Cladonema jellyfish, and myoinhibitory peptide, a neuropeptide that regulates feeding in fruit flies, they decided to test whether they could exchange the two. Their success in doing so highlights the deep evolutionary origins of feeding regulation.
Published Engineered plants produce sex perfume to trick pests and replace pesticides
(via sciencedaily.com) Original source Tobacco plants have been engineered to manufacture an alluring perfume of insect sex pheromones, which could be used to confuse would-be pests looking for love and reduce the need for harmful pesticides.
Published Here's how a worm's embryonic cells changed its development potential
(via sciencedaily.com) Original source Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary information for cell differentiation is mostly ingrained within DNA and other genetic factors.
Published Woolly mammoths evolved smaller ears and woolier coats over the 700,000 years that they roamed the Siberian steppes
(via sciencedaily.com) Original source A team of researchers compared the genomes of woolly mammoths with modern day elephants to find out what made woolly mammoths unique, both as individuals and as a species. The investigators report that many of the woolly mammoth's trademark features -- including their woolly coats and large fat deposits -- were already genetically encoded in the earliest woolly mammoths, but these and other traits became more defined over the species' 700,000+ year existence. They also identified a gene with several mutations that may have been responsible for the woolly mammoth's miniscule ears.
Published Simple but revolutionary modular organoids
(via sciencedaily.com) Original source A team has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without using elaborate techniques. The group also recently demonstrated the ability to use the device to build organoids that faithfully reproduce the asymmetric genetic expression that characterizes the actual development of organisms.
Published Researchers clear the way for well-rounded view of cellular defects
(via sciencedaily.com) Original source New research investigates how cells divide, particularly in the fibrous environment of living tissue. Cells are typically studied in a flat environment, and the difference between flat and fibrous landscapes opens new windows into the behavior of cells and the diseases that impact them.
Published Researchers create embryo-like structures from monkey embryonic stem cells
(via sciencedaily.com) Original source Human embryo development and early organ formation remain largely unexplored due to ethical issues surrounding the use of embryos for research as well as limited availability of materials to study. Investigators now report on the creation of embryo-like structures from monkey embryonic stem cells. The investigators also transferred these embryo-like structures into the uteruses of female monkeys and determined that the structures were able to implant and elicit a hormonal response similar to pregnancy.
Published A miniature heart in a petri dish: Organoid emulates development of the human heart
(via sciencedaily.com) Original source A team has induced stem cells to emulate the development of the human heart. The result is a sort of 'mini-heart' known as an organoid. It will permit the study of the earliest development phase of our heart and facilitate research on diseases.
Published Study to decode microbe-gut signaling suggests potential new treatment for IBD
(via sciencedaily.com) Original source Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.
Published One of Swedish warship Vasa's crew was a woman
(via sciencedaily.com) When the human remains found on board the Swedish warship Vasa (1628) were investigated, it was determined that the skeleton designated G was a man. New research now shows that the skeleton is actually from a woman. About thirty people died when Vasa sank on its maiden voyage in Stockholm, 1628. We cannot know who most of them were, only one person is named in the written sources. When the ship was raised in 1961 it was the scene of a comprehensive archaeological excavation, in which numerous human bones were found on board and examined.
Published Microrobot technology: Externally connecting in vivo neural networks
(via sciencedaily.com) Researchers have developed a technology for delivering a microrobot to a target point of a hippocampus in an in-vitro environment, connecting neural networks, and measuring neural signals. The findings are expected to contribute to neural network research and the verification and analysis of cell therapy products.
Published Boosting the body's anti-viral immune response may eliminate aging cells
(via sciencedaily.com) Original source Aging cells express a protein that is produced by human cytomegalovirus and is targeted by certain immune cells in the body. Harnessing the immune response to this protein could have multiple health benefits during aging.
Published T cells in human blood secrete a substance that affects blood pressure and inflammation
(via sciencedaily.com) Original source Acetylcholine regulates blood flow, but the source of blood acetylcholine has been unclear. Now, researchers have discovered that certain T cells in human blood can produce acetylcholine, which may help regulate blood pressure and inflammation. The study also demonstrates a possible association between these immune cells in seriously ill patients and the risk of death.
Published Components of cytoskeleton strengthen effect of sex hormones
(via sciencedaily.com) Researchers discover that actin acts in the cell nucleus and is partly responsible for the expression of male sexual characteristics.