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Categories: Archaeology: General, Biology: Developmental
Published Surprisingly simple model explains how brain cells organize and connect



A new study by physicists and neuroscientists describes how connectivity among neurons comes about through general principles of networking and self-organization, rather than the biological features of an individual organism.
Published Stalagmites as climate archive



When combined with data from tree-ring records, stalagmites can open up a unique archive to study natural climate fluctuations, a research team has demonstrated. The researchers analyzed the isotopic composition of oxygen in a stalagmite formed from calcareous water in a cave in southern Germany. In conjunction with the data acquired from tree rings, they were able to reconstruct short-term climate fluctuations over centuries and correlate them with historically documented environmental events.
Published Woolly mammoth movements tied to earliest Alaska hunting camps



Researchers have linked the travels of a 14,000-year-old woolly mammoth with the oldest known human settlements in Alaska, providing clues about the relationship between the iconic species and some of the earliest people to travel across the Bering Land Bridge. Isotopic data, along with DNA from other mammoths at the site and archaeological evidence, indicates that early Alaskans likely structured their settlements to overlap with areas where mammoths congregated. Those findings, highlighted in the new issue of the journal Science Advances, provide evidence that mammoths and early hunter-gatherers shared habitat in the region. The long-term predictable presence of woolly mammoths would have attracted humans to the area.
Published Key moment in the evolution of life on Earth captured in fossils



New research has precisely dated some of the oldest fossils of complex multicellular life in the world, helping to track a pivotal moment in the history of Earth when the seas began teeming with new lifeforms -- after four billion years of containing only single-celled microbes.
Published Bioinformatics: Researchers develop a new machine learning approach



To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.
Published 3D in vitro human atherosclerosis model for high-throughput drug screening



A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.
Published Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging



Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.
Published Aging mouse sperm affects MicroRNA, increasing the risk of neurodevelopmental disorders



Much is known about the added complication to pregnancy when it comes to the age of the mother, but recent studies show that the age of the father can also heighten the risk of neurodevelopmental disorders. A team of researchers has explored the impacts of paternal aging on microRNAs, the molecules that play a crucial role in regulating gene expression.
Published Lab-grown retinas explain why people see colors dogs can't



With human retinas grown in a petri dish, researchers discovered how an offshoot of vitamin A generates the specialized cells that enable people to see millions of colors, an ability that dogs, cats, and other mammals do not possess. The findings increase understanding of color blindness, age-related vision loss, and other diseases linked to photoreceptor cells. They also demonstrate how genes instruct the human retina to make specific color-sensing cells, a process scientists thought was controlled by thyroid hormones.
Published Oldest known fossilized skin is 21 million years older than previous examples



Researchers have identified a 3D fragment of fossilized skin that is at least 21 million years than previously described skin fossils. The skin, which belonged to an early species of Paleozoic reptile, has a pebbled surface and most closely resembles crocodile skin. It's the oldest example of preserved epidermis, the outermost layer of skin in terrestrial reptiles, birds, and mammals, which was an important evolutionary adaptation in the transition to life on land.
Published Protein complex discovered to control DNA repair



The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team has now discovered a previously unrecognized control point for these processes. This could lead to a new approach for the development of cancer therapies aimed at inhibiting the repair of damaged cancer cells.
Published Ancient cities provide key datasets for urban planning, policy and predictions in the Anthropocene



A new study shows how state-of-the-art methods and perspectives from archaeology, history, and palaeoecology are shedding new light on 5,500 years of urban life.
Published Prehistoric person with Turner syndrome identified from ancient DNA



Researchers have developed a new technique to measure the number of chromosomes in ancient genomes more precisely, using it to identify the first prehistoric person with mosaic Turner syndrome (characterized by one X chromosome instead of two [XX]), who lived about 2500 years ago.
Published Discovery of immense fortifications dating back 4,000 years in north-western Arabia



The North Arabian Desert oases were inhabited by sedentary populations in the 4th and 3rd millennia BCE. A fortification enclosing the Khaybar Oasis -- one of the longest known going back to this period -- was just revealed by a team of scientists. This new walled oasis is, along with that of Tayma, one of the two largest in Saudi Arabia.
Published Study on lamprey embryos sheds light on the evolutionary origin of vertebrate head



Scientists have investigated lamprey embryos using cutting-edge microscopic techniques to reveal interesting insights about vertebrate head evolution, clarifying an unresolved mystery in basic science.
Published The extinction of the giant ape: Long-standing mystery solved



The largest ever primate Gigantopithecus blacki went extinct when other Asian great apes were thriving, and its demise has long been a mystery. A massive regional study of 22 caves in southern China explores a species on the brink of extinction between 295,000 and 215,000 years ago. As the environment became more seasonal, forest plant communities changed Primates such as orangutans adapted their eating habits and behaviors in response but G. blacki showed signs of stress, struggled to adapt and their numbers dwindled.
Published Smart skin bacteria are able to secrete and produce molecules to treat acne



An experimental study has shown that a type of skin bacterium can efficiently be engineered to produce a protein to regulate sebum production. This application could treat acne without compromising the homeostasis of the entire skin microbiome.
Published Stranger than friction: A force initiating life



As the potter works the spinning wheel, the friction between their hands and the soft clay helps them shape it into all kinds of forms and creations. In a fascinating parallel, sea squirt oocytes (immature egg cells) harness friction within various compartments in their interior to undergo developmental changes after conception.
Published Large-scale mapping of pig genes could pave the way for new human medicines



Researchers have carried out complex genetic analyses of hundreds of pigs and humans to identify differences and similarities. This new knowledge can be used to ensure healthier pigs for farmers and can help the pharmaceutical industry breed better laboratory pigs for testing new medicines.
Published Nine new snail species discovered in Papua New Guinea, a biodiversity hot spot at risk



A new study describes nine new species of carnivorous land snails, all of which are so small they could fit together on a U.S. nickel. They present a rare opportunity to study a group that in many other places is disappearing fast. Worldwide, mollusks account for more than 50% of all recorded extinctions since the year 1500, and many of these were land snails from Pacific islands.