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Categories: Archaeology: General, Biology: Developmental

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Newly discovered iron storage 'ferrosomes' inside the bacterium C. diff -- the leading cause of hospital-acquired infections -- are important for infection in an animal model and could offer new targets for antibacterial drugs. They also represent a rare demonstration of a membrane-bound structure inside a pathogenic bacterium, upsetting the biological dogma that bacteria do not contain organelles. 

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An international research team has made an unexpected discovery of a biased counting mechanism used by the single-celled green alga Chlamydomonas to control cell division. 

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A new study casts doubt on claims that Homo naledi, a small-brained hominin dating to between 335-241,000 years ago, deliberately buried their dead and produced rock art in Rising Star Cave, South Africa. Recent articles suggested the recent excavations at the Rising Star Cave system provided evidence of at least three burial features, two in the Dinaledi Chamber and a third in the Hill Antechamber cavity. The group of experts have now called for a deeper dig into the science behind the findings.

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Researchers are working to understand how protein quality control works in cells. 

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An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.

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A bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone and blood in vertebrate embryos. The team of researchers is using a new approach, called the Synthetic Processing (SynPro) system, in zebrafish to study how Vg1 is formed. By learning the molecular rules of signal formation in a developing animal, researchers aim to engineer mechanisms -- such as giving cells new instructions -- that could play a role in treating or preventing disease.

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Scientists used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

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A team of researchers has reported for the first time the live birth of a monkey that contains a high proportion of cells derived from a monkey stem cell line. This 'chimeric' monkey is composed of cells that originate from two genetically distinct embryos of the same species of monkey. This has previously been demonstrated in rats and mice but, until now, has not been possible in other species, including non-human primates.

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While we all aspire for a long lifespan, what is most coveted is a long period of vigor and health, or 'healthspan,' that precedes the inevitable decline of advancing age. Researchers have discovered that instruments of death that cells use to commit suicide when things go wrong contribute to making a longer and healthier life by revitalizing the specialized cellular compartments called mitochondria.

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Researchers have mapped on an atomic level what happens in a virus particle when the temperature is raised.

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New research helps explain how sharp patterns form on zebras, leopards, tropical fish and other creatures. Their findings could inform the development of new high-tech materials and drugs.

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A new analysis of lice genetic diversity suggests that lice came to the Americas twice -- once during the first wave of human migration across the Bering Strait, and again during European colonization.

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Researchers have combined over seven synthetic chromosomes that were made in the lab into a single yeast cell, resulting in a strain with more than 50% synthetic DNA that survives and replicates similarly to wild yeast strains. A global consortium is working to develop the first synthetic eukaryote genome from scratch. The team has now synthesized and debugged all sixteen yeast chromosomes.

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A team of Scientists has completed construction of a synthetic chromosome as part of a major international project to build the world's first synthetic yeast genome. The work represents completion of one of the 16 chromosomes of the yeast genome, which is part of the biggest project ever in synthetic biology; the international synthetic yeast genome collaboration. The collaboration, known as 'Sc2.0' has been a 15-year project involving teams from around the world (UK, US, China, Singapore, UK, France and Australia), working together to make synthetic versions of all of yeast's chromosomes. Alongside this paper, another 9 publications are also released today from other teams describing their synthetic chromosomes. The final completion of the genome project -- the largest synthetic genome ever -- is expected next year.

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Researchers have discovered a link between obesity and neurodegenerative disorders like Alzheimer's disease. Using the common fruit fly, the research shows that a high-sugar diet -- a hallmark of obesity -- causes insulin resistance in the brain, which in turn reduces the ability to remove neuronal debris, thus increasing the risk of neurodegeneration.

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New research combines microscope and video technology to analyze how different species develop, and how changes in the timings of any developments can be tracked. A detailed analysis of the Energy Proxy Traits (EPTs) that result from these processes has provided researchers with the first evidence that traditionally measured timings of developmental events are associated with far broader changes to the full set of an embryo's observable characteristics.

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The hunter-gatherers who settled on the banks of the Haine, a river in southern Belgium, 31,000 years ago were already using spearthrowers to hunt their game. The material found at the archaeological site of Maisières-Canal permits establishing the use of this hunting technique 10,000 years earlier than the oldest currently known preserved spearthrowers. This discovery is prompting archaeologists to reconsider the age of this important technological innovation.

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Researchers have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.

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Researchers have identified a gene which is an early determining factor of ovary development in mice.

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An international team of researchers has discovered that formaldehyde, a widely spread pollutant and common metabolite in our body, interferes in the epigenetic programming of the cell. This finding expands the knowledge of formaldehyde, previously considered only as a DNA mutagen, and helps establishing a further link with cancer.