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Categories: Biology: Developmental, Paleontology: General
Published Researchers solve mystery behind DnaA protein's role in DNA replication initiation
(via sciencedaily.com) Original source Scientists have uncovered how DnaA, the master key to DNA replication, opens the door to bacterial growth. This breakthroughpaves the way for new antibiotics to combat the rising tide of antibiotic resistance.
Published New insights revealed on tissue-dependent roles of JAK signaling in inflammation
(via sciencedaily.com) Original source Researchers have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.
Published How researchers are 'CReATiNG' synthetic chromosomes faster and cheaper
(via sciencedaily.com) Original source A new technique to clone and reassemble DNA, dubbed CReATiNG, could simplify and lower the cost to make synthetic chromosomes. Potential applications are numerous, including pharmaceutical production, biofuel generation, cancer therapies, and environmental cleanup using modified organisms. The method adds a powerful, versatile tool to the burgeoning field of synthetic biology.
Published Unveiling ancient secrets: 3D preservation of trilobite soft tissues sheds light on convergent evolution of defensive enrollment
(via sciencedaily.com) Original source Researchers describe unusual trilobite fossils prepared as thin sections showing the 3D soft tissues during enrollment. The study reveals the soft undersides of enrolled trilobites and the evolutionary mechanism that allows arthropods to enroll their bodies for protection from predators and adverse environmental conditions.
Published A trillion scents, one nose
(via sciencedaily.com) Original source A research team has uncovered a previously undetected mechanism in mice -- starring the genetic molecule RNA -- that could explain how each sensory cell, or neuron, in mammalian noses becomes tailored to detect a specific odor chemical.
Published Cells of the future: A key to reprogramming cell identities
(via sciencedaily.com) Original source The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time. Scientists have recently uncovered a fascinating aspect of this process known as 'replication timing' (RT) and how special this is when life commences.
Published New study examines the relationship between the rate of wound healing, the circadian rhythm, and 'hair' on cells
(via sciencedaily.com) Original source Nearly every organism on Earth follows a natural circadian rhythm that is coded by your cell's clock genes, which do exactly as you suspect from the name: regulate your body's rhythm on a 24-hour basis. Most cells in mammalian bodies have cilia of some sort, which are hair-like structures that perform a variety of functions such as movement for motile cilia and aiding in structure in function for non-motile, or primary, cilia. The primary cilia also act as a sensory organ for the cell, a function which has illuminated the primary cilia's potential role in the healing process and how bodies heal at a different rate according to our circadian rhythm. In this research, the role of the primary cilia, biological clock and wound healing is explored.
Published Single-celled protists in the guts of animals thrive without the 'powerhouse of the cell'
(via sciencedaily.com) Original source Almost all eukaryotic organisms, from plants and animals to fungi, can't survive without mitochondria -- the 'powerhouses of the cell,' which generate chemical energy using oxygen. However, a new study finds that multiple members of the oxymonads, a group of single-celled protists that live inside the guts of termites and other animals, have evolved to live quite happily without them.
Published Mysterious fruit shown to be the oldest known fossils of the Frankincense and Myrrh family
(via sciencedaily.com) Original source Early in the 1970s, paleontologists discovered strange fossilized fruits between hardened rock from one of the largest volcanic eruptions in Earth's history. The identity of these fossils remained elusive for the next several decades. Using CT scanning, scientists have now determined they are the oldest fossils from species in the Frankincense and Myrrh family.
Published Genetic atlas detailing early stages of zebrafish development
(via sciencedaily.com) Original source Researchers have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a period in which embryos mature from a single cell into distinct cell types.
Published Morocco earthquake had unusual deep slip, according to new modeling
(via sciencedaily.com) Original source In their rapid characterization of the magnitude 6.8 Al Haouz earthquake in Morocco, researchers suggest that the earthquake ruptured roughly 25 kilometers deep beneath the surface.
Published Can you change a chicken into a frog, a fish or a chameleon?
(via sciencedaily.com) Original source Researchers have developed a theoretical framework that can reproduce and predict the patterns associated with gastrulation in a chicken embryo.
Published How the immune system fights to keep herpes at bay
(via sciencedaily.com) Original source In a study of lab-engineered cells, researchers identify how the immune system neutralizes the herpesvirus. The research maps, for the first time, the maneuvers used by virus and host in the cell nucleus, a poorly understood terrain of host-pathogen interaction. The findings could inform the design of new treatments for herpes and other viruses that replicate in the same way.
Published AI provides more accurate analysis of prehistoric and modern animals, painting picture of ancient world
(via sciencedaily.com) Original source A new study of the remains of prehistoric and modern African antelopes found that AI technology accurately identified animals more than 90% of the time compared to humans, who had much lower accuracy rates depending on the expert.
Published Enzymes can't tell artificial DNA from the real thing
(via sciencedaily.com) Original source Researchers have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab.
Published Scientists unveil complete cell map of a whole mammalian brain
(via sciencedaily.com) Original source Researchers have created a complete cell atlas of a whole mammalian brain. This atlas serves as a map for the mouse brain, describing the type, location, and molecular information of more than 32 million cells and providing information on connectivity between these cells.
Published Cells move in groups differently than they do when alone
(via sciencedaily.com) Original source A protein that helps generate the force needed for single cells to move works differently in cells moving in groups, a new study shows.
Published Mice possess natural gene therapy system
(via sciencedaily.com) Original source A previously mysterious small RNA molecule in mice is found to play a crucial role in gene expression, and may be the first identified member of a new class of regulatory RNAs.
Published A rare enzyme role change with bacterial defense system assembly
(via sciencedaily.com) Original source Scientists have revealed a never-before-seen phenomenon in a protein: Alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound to help bacteria commit suicide.
Published Best areas for rewilding European bison
(via sciencedaily.com) Original source Simulations integrate historical records, fossils, and ancient DNA to reveal why the European bison nearly went extinct, and pinpoint optimal areas for conservation. Since the near-extinction of the European bison, enormous conservation efforts have helped to restore wild populations, and its numbers are on the rise. However, the study authors argue that ensuring the species's long-term protection and recovery requires understanding why they nearly went extinct in the first place. 'Our study also suggests areas where rewilding attempts are most likely to be successful,' said lead author July Pilowsky, currently a disease ecologist at Cary Institute of Ecosystem Studies. Pilowsky completed the research while working on their PhD at University of Adelaide and University of Copenhagen.