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Categories: Biology: Developmental, Paleontology: General
Published Palaeo-CSI: Mosasaurs were picky eaters



Mosasaurs, those large marine reptiles from the long-gone Cretaceous world, were quite picky in their choice of diet. Researchers came to this conclusion after studying the wear marks on mosasaur teeth.
Published First live birth of a chimeric monkey using embryonic stem cell lines



A team of researchers has reported for the first time the live birth of a monkey that contains a high proportion of cells derived from a monkey stem cell line. This 'chimeric' monkey is composed of cells that originate from two genetically distinct embryos of the same species of monkey. This has previously been demonstrated in rats and mice but, until now, has not been possible in other species, including non-human primates.
Published Zen and the art of mitochondrial maintenance: The machinery of death makes a healthier life



While we all aspire for a long lifespan, what is most coveted is a long period of vigor and health, or 'healthspan,' that precedes the inevitable decline of advancing age. Researchers have discovered that instruments of death that cells use to commit suicide when things go wrong contribute to making a longer and healthier life by revitalizing the specialized cellular compartments called mitochondria.
Published Temperature increase triggers viral infection



Researchers have mapped on an atomic level what happens in a virus particle when the temperature is raised.
Published How animals get their stripes and spots



New research helps explain how sharp patterns form on zebras, leopards, tropical fish and other creatures. Their findings could inform the development of new high-tech materials and drugs.
Published Yeast with an over half synthetic genome is created in the lab



Researchers have combined over seven synthetic chromosomes that were made in the lab into a single yeast cell, resulting in a strain with more than 50% synthetic DNA that survives and replicates similarly to wild yeast strains. A global consortium is working to develop the first synthetic eukaryote genome from scratch. The team has now synthesized and debugged all sixteen yeast chromosomes.
Published Scientists take major step towards completing the world's first synthetic yeast



A team of Scientists has completed construction of a synthetic chromosome as part of a major international project to build the world's first synthetic yeast genome. The work represents completion of one of the 16 chromosomes of the yeast genome, which is part of the biggest project ever in synthetic biology; the international synthetic yeast genome collaboration. The collaboration, known as 'Sc2.0' has been a 15-year project involving teams from around the world (UK, US, China, Singapore, UK, France and Australia), working together to make synthetic versions of all of yeast's chromosomes. Alongside this paper, another 9 publications are also released today from other teams describing their synthetic chromosomes. The final completion of the genome project -- the largest synthetic genome ever -- is expected next year.
Published Why a surprising discovery, warming seas and the demise of the 'Meg' may spell trouble for more and more sharks



Some unexpected shark strandings and subsequent surprises following autopsies have, ironically, taken marine biologists millions of years back in time as they look to the future with concern. Adding chapters to an evolutionary tale involving the infamous megalodon shark (the 'Meg'), they think their work suggests there are more warm-blooded sharks out there than previously believed, and -- based on the Meg's demise -- these species may be at great risk from warming seas.
Published Obesity linked to neurodegeneration through insulin resistance



Researchers have discovered a link between obesity and neurodegenerative disorders like Alzheimer's disease. Using the common fruit fly, the research shows that a high-sugar diet -- a hallmark of obesity -- causes insulin resistance in the brain, which in turn reduces the ability to remove neuronal debris, thus increasing the risk of neurodegeneration.
Published Window to the past: New microfossils suggest earlier rise in complex life



Microfossils may capture a jump in the complexity of life that coincided with the rise of oxygen in Earth's atmosphere and oceans, according to an international team of scientists.
Published 450-million-year-old organism finds new life in Softbotics



Researchers have used fossil evidence to engineer a soft robotic replica of pleurocystitids, a marine organism that existed nearly 450 million years ago and is believed to be one of the first echinoderms capable of movement using a muscular stem.
Published Video technology could transform how scientists monitor changes in species evolution and development



New research combines microscope and video technology to analyze how different species develop, and how changes in the timings of any developments can be tracked. A detailed analysis of the Energy Proxy Traits (EPTs) that result from these processes has provided researchers with the first evidence that traditionally measured timings of developmental events are associated with far broader changes to the full set of an embryo's observable characteristics.
Published Fossils tell tale of last primate to inhabit North America before humans



Paleontologists have shed light on the long-standing saga of Ekgmowechashala, based on fossil teeth and jaws found in both Nebraska and China. Ekgmowechashala is the last primate found in the fossil record before humans.
Published Frogs were Florida's first-known vertebrates from the Caribbean



A new fossil study shows that frogs from the genus Eleutherodactylus are geologically the oldest Caribbean vertebrates to be found in Florida. They made the journey 20 million years ago, when much of Florida was still underwater.
Published Research outlines how sex differences have evolved



Researchers have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.
Published Female sex determining gene identified in mice



Researchers have identified a gene which is an early determining factor of ovary development in mice.
Published A known environmental hazard can change the epigenetics of cells



An international team of researchers has discovered that formaldehyde, a widely spread pollutant and common metabolite in our body, interferes in the epigenetic programming of the cell. This finding expands the knowledge of formaldehyde, previously considered only as a DNA mutagen, and helps establishing a further link with cancer.
Published Immunology: Dysfunction of mitochondria drives the exhaustion of T cells



In the immune system's fight against cancer and infections, the T cells often lose their power. Now immunologists may have found a possible explanation for this phenomenon.
Published New study sheds light on the molecular mechanisms underlying lipid recycling within cells



Our understanding of how cells recycle lipids through autophagy -- a form of cellular degradation -- has grown significantly, thanks to a recent study. Using yeast as a model organism, the researchers explored the molecular mechanisms leading to the degradation of the phospholipid bilayers making up the cell membranes. Their findings improve our understanding of cellular degradation processes and related metabolic disorders.
Published 'Jurassic worlds' might be easier to spot than modern Earth



An analysis finds telescopes could better detect potential chemical signatures of life in an Earth-like exoplanet that more closely resembles the age the dinosaurs inhabited than the one we know today.