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Categories: Biology: Developmental, Paleontology: Dinosaurs
Published Research shows how RNA 'junk' controls our genes



Researchers have made a significant advance in understanding how genes are controlled in living organisms. The new study focuses on critical snippets of RNA in the tiny, transparent roundworm Caenorhabditis elegans (C. elegans). The study provides a detailed map of the 3'UTR regions of RNA in C. elegans. 3'UTRs (untranslated regions) are segments of RNA involved in gene regulation.
Published Researchers thwart resistant bacteria's strategy



Bacteria are experts at evolving resistance to antibiotics. One resistance strategy is to cover their cell walls in sticky and gooey biofilm that antibiotics cannot penetrate. A new discovery could put a stop to this strategy.
Published Sixty-million-year-old grape seeds reveal how the death of the dinosaurs may have paved the way for grapes to spread



Scientists discovered the oldest fossil grapes in the Western Hemisphere, which help show how after the death of the dinosaurs, grapes spread across the world.
Published New, holistic way to teach synthetic biology



Synthetic biology combines principles from science, engineering and social science, creating emerging technologies such as alternative meats and mRNA vaccines; Deconstructing synthetic biology across scales gives rise to new approach to uniting traditional disciplines; Case studies offer a modular, accessible approach to teaching at different institutions.
Published From takeoff to flight, the wiring of a fly's nervous system is mapped



Although a fly's motor neurons are few, it performs remarkable aerial and terrestrial feats. A wiring diagram recently created of the motor circuits in the central nervous system of the fruit fly is providing detailed information on how the nerve coordination of leg movements differs from that controlling the wings. Such studies reveal the unexpected complexity of the fly's tiny motor system. They also advance the understanding of how the central nervous system in animals coordinates individual muscles to carry out a variety of behaviors.
Published Cell division: Before commitment, a very long engagement



Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours -- sometimes more than a day -- in a reversible intermediate state, according to a new discovery. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.
Published The on-and-off affair in DNA



Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via the interactions of two other proteins and histone marks. The molecular mechanisms demonstrate that rather than functioning as a simple 'off switch,' H3K9 methylation is more like a 'dimmer switch' that fine-tunes DNA transcription. The discovery suggests there might be similar mechanisms in other organisms, too.
Published Slipping a note to a neighbor: The cellular way



Study reveals how drug molecules bind in channels between neighboring cells, changing intercellular communication.
Published Zebrafish reveal how bioelectricity shapes muscle development



New research describes how nerve cells and muscle cells communicate through electrical signals during development -- a phenomenon known as bioelectricity. The communication, which takes place via specialized channels between cells, is vital for proper development and behavior. The study identifies specific genes that control the process, and pins down what happens when it goes wrong. The finding offers clues to the genetic origins of muscle disorders in humans.
Published Discovery of vast sex differences in cellular activity has major implications for disease treatment



The study reveals vast differences in gene activity within the mitochondria of males compared to females. This is the first study to test effects of all 37 genes in the mitochondrial genome -- genes that copepods and humans share. The study found that males demonstrate more activity across all protein-coding mitochondrial genes than females. Although the study looks at tiny marine organisms called copepods, the findings have weighty implications for human medicine.
Published How cells boost gene expression



The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins -- yet it exists in large quantities. A research team has now discovered an important function of antisense RNA (asRNA): the researchers found that asRNA acts as a 'superhighway' in cell transport and thus accelerates gene expression.
Published How to make aging a 'fairer game' for all wormkind



Researchers have discovered a new fundamental mechanism governing the rules of ageing in worms. The researchers were able to manipulate the mechanism through genetic interventions which dramatically extend not just the lifespan of the worms, but also their health-span. In other words, trading weak, frail old age with vigorous golden years -- all without altering their diet, environment or other external factors.
Published New study finds dinosaur fossils did not inspire the mythological griffin



For centuries, scientists thought they knew where the griffin legend came from. A new study takes a closer look at the data and folklore's influence on science.
Published Newly discovered dinosaur boasts big, blade-like horns



A new dinosaur has been identified and named. The dinosaur's name, Lokiceratops rangiformis, translates roughly to 'Loki's horned face that looks like a caribou.'
Published Where to put head and tail?



Formation of the body axes is a critical part of embryonic development. They guarantee that all body parts end up where they belong and that no ears grow on our backs. The head-tail axis, for example, determines the orientation of the two ends of the body. It was previously assumed that this axis is largely determined by the interplay between the Nodal and BMP signals. However, there appears to be another player in this system, as researchers have now discovered by using an embryo-like model system they developed. In the absence of BMP, the signalling molecule beta-catenin takes on the role of the Nodal antagonist. This new mechanism could be a flexible solution for axis formation in embryos with different shapes.
Published Ancient polar sea reptile fossil is oldest ever found in Southern Hemisphere



An international team of scientists has identified the oldest fossil of a sea-going reptile from the Southern Hemisphere -- a nothosaur vertebra found on New Zealand's South Island. 246 million years ago, at the beginning of the Age of Dinosaurs, New Zealand was located on the southern polar coast of a vast super-ocean called Panthalassa. 'The nothosaur found in New Zealand is over 40 million years older than the previously oldest known sauropterygian fossils from the Southern Hemisphere.
Published The genetic 'switches' of bone growth



In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone. They are controlled by other sequences in the genome, called enhancers, which, like switches, activate or deactivate them as required. A team has now identified and located 2700 enhancers -- among millions of non-coding genetic sequences -- that precisely regulate the genes responsible for bone growth. This discovery sheds light on one of the major factors influencing the size of individuals in adulthood, and explains why their failure could be the cause of certain bone malformations.
Published Are plants intelligent? It depends on the definition



Goldenrod can perceive other plants nearby without ever touching them, by sensing far-red light ratios reflected off leaves. When goldenrod is eaten by herbivores, it adapts its response based on whether or not another plant is nearby. Is this kind of flexible, real-time, adaptive response a sign of intelligence in plants?
Published Virus-like nanoparticles control the multicellular organization and reproduction of host bacteria



Researchers have discovered that virus-like nanoparticles can promote the multicellular organization and reproduction of host bacteria. These particles, which are evolutionarily related to phages (viruses that infect bacteria), contain an enzyme that helps shape the multicellular architecture and ultimately enhances morphological differentiation.
Published Algae offer real potential as a renewable electricity source



The need to transition away from fossil fuels to more sustainable energy production is critical. That's why a team of researchers is looking at a potential power source that not only produces no carbon emissions but removes carbon as it works: algae.