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Categories: Biology: Developmental, Chemistry: General

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     (via sciencedaily.com)     Original source 

Animals and fungi predominantly use two different modes of cell division -- called open and closed mitosis, respectively. A new study has shown that different species of Ichthyosporea -- marine protists that are close relatives of both animals and fungi -- use either open and closed mitosis, closely correlated to whether the species has multinucleate life cycle stages. The study demonstrates the way animals do cell division might have evolved long before animals themselves did and how this is linked to an organism's life cycle.

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Researchers found that adding a newly developed modified sugar, BNAP-AEO, to gapmer antisense oligonucleotides (ASOs) increased their affinity for target RNAs, thus significantly enhancing their gene-silencing effects in vitro and in vivo. The BNAP-AEO modification also decreased gapmer ASO toxicity to the central nervous system (CNS), suggesting that it could improve the clinical application of ASO treatment of CNS disease.

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Researchers have used computational design methods to develop non-metal organic porous framework materials, with potential applications in areas such as catalysis, water capture or hydrogen storage.

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Engineers have found a way to eliminate the buildup of scar tissue around implantable devices, by coating them with a hydrogel adhesive. The material binds the device to tissue and prevents the immune system from attacking the device.

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Scientists have uncovered the properties of a rare earth element that was first discovered 80 years ago at the very same laboratory, opening a new pathway for the exploration of elements critical in modern technology, from medicine to space travel.

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Researchers trained an AI model to accurately predict male fruit flies' courtship behavior in response to any sight of a female. This breakthrough offers new insight into how the brain processes visual data and may someday pave the way for artificial vision technology.

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In a new study, a team of researchers used research on fossilizing techniques to create a new method for sealing cracks and fractures in rocks and bedrock using a 'concretion-forming resin'. This innovative technique has applications in a wide range of industries, from tunnel construction to long-term underground storage of hazardous materials.

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Engineers have modeled a new way to recycle polystyrene that could become the first viable way of making the material reusable.

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Use of the greenhouse gas CO2 as a chemical raw material would not only reduce emissions, but also the consumption of fossil feedstocks. A novel metal-free organic framework could make it possible to electrocatalytically produce ethylene, a primary chemical raw material, from CO2. Nitrogen atoms with a particular electron configuration play a critical role for the catalyst.

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Researchers describe cell-in-cell phenomena in which one cell engulfs and sometimes consumes another. The study shows that cases of this behavior, including cell cannibalism, are widespread across the tree of life. The findings challenge the common perception that cell-in-cell events are largely restricted to cancer cells. Rather, these events appear to be common across diverse organisms, from single-celled amoebas to complex multicellular animals.

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Two new studies detail the changes seen at the single-cell level in pig organs and recipient human bodies before, during, and just after the xenotransplantation surgeries in the decedents.

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A team of geologists analyzed 3,500 samples taken in and around coal mines in Utah and Colorado. Their findings open the possibility that these mines could see a secondary resource stream in the form of rare earth metals used in renewable energy and numerous other high-tech applications.

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Investigating ways to create high-performance steel, a research team used theoretical calculations on 120 combinations of 12 alloy elements, such as aluminum and titanium, with carbon and nitrogen, while also systematically clarifying the bonding mechanism.

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From the small ossicones on a giraffe to the gigantic antlers of a male moose -- which can grow as wide as a car -- the headgear of ruminant hooved mammals is extremely diverse, and new research suggests that despite the physical differences, fundamental aspects of these bony adaptations likely evolved from a common ancestor.

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Two newly discovered mechanisms in bacteria have been identified that can contribute to the development of antibiotic resistance. Changing the number of copies of resistance genes in bacteria increases antibiotic resistance, and can do so very quickly. These two mechanisms, along with a third known mechanism, can occur independently of each other, even within the same bacterial cell.

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Researchers have unveiled that myriad, intricate factors influence the genesis and chemistry of bastnasite and rare earth carbonates, which are critically needed for today's tech industry and its hardware outputs. Their work unveils a newly acquired depth of understanding that had previously been unexplored in this field. In combination, the findings mark a significant advancement and promise to reshape our understanding of rare earth mineral formation.

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A new study of prion diseases, using a human cerebral organoid model, suggests there is a substantial species barrier preventing transmission of chronic wasting disease (CWD) from cervids -- deer, elk and moose -- to people. The findings are consistent with decades of similar research in animal models.

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A new commentary paper puts forth a transformative solution to the unsustainable reliance on fossil resources by the chemical industry: catalysis to leverage sustainable waste resources, ushering the industry from a linear to a circular economy.

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Plants have special corrective molecules at their disposal that can make retrospective modifications to copies of genes. However, it would appear that these 'Tipp-Ex proteins' do not have permission to work in all areas of the cell, only being used in chloroplasts and mitochondria. A study has now explained why this is the case. It suggests that the correction mechanism would otherwise modify copies that have nothing wrong with them, with fatal consequences for the cell.

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If fruit fly wings do not develop into the right shape, the flies will die. Researchers have learned how fly embryo cells develop as they need to, opening a window into human development and possible treatments for birth defects.