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Categories: Biology: Developmental, Chemistry: General

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Researchers have made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides. Mistakes in chromosome segregation can lead to cell death and cancer development. The researchers discovered that the centromere consists of two subdomains. This fundamental finding has important implications for the process of chromosome segregation and provides new mechanisms underlying erroneous divisions in cancer cells. The research was published in Cell on May 13th 2024.

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Collaborative efforts decode the mechanism behind stabilizing cathode doping in electric vehicle batteries.

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Introns are perhaps one of our genome's biggest mysteries. They are DNA sequences that interrupt the sensible protein-coding information in your genes, and need to be 'spliced out.'

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Researchers have taken a key step toward closing the silver nanoparticles knowledge gap with a study that indicates the particles' shape and surface chemistry play key roles in how they affect aquatic ecosystems.

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The tool will help researchers better understand major challenges that afflict undernourished children, such as changes in cognitive development and higher infection rates.

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A method has been discovered to treat water heavily contaminated with unhealthful forever chemicals, known by chemists as PFAS or poly- and per-fluoroalkyl substances. It involves treating heavily contaminated water with ultraviolet (UV) light, sulfite, and a process called electrochemical oxidation. It breaks up strong fluorine-to-carbon bonds in the PFAS compounds and other concentrated organic compounds in heavily polluted water. The reaction also occurs at room temperature without a need for additional heat or high pressure. This method is expected to be useful in cleanups of PFAS pollution from decades of fire suppressant foam use at military facilities.

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In a study of a species of African butterfly, researchers have discovered a previously undescribed molecular mechanism of how the sex of an embryo is initially specified.

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Perovskites are among the most researched topics in materials science. Recently, a research team has solved an age-old challenge to synthesize all-organic two-dimensional perovskites, extending the field into the exciting realm of 2D materials. This breakthrough opens up a new field of 2D all-organic perovskites, which holds promise for both fundamental science and potential applications.

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The global chemical industry is a major fossil fuel consumer and climate change contributor; however, new research has identified how the sector could clean up its green credentials by getting dirty.

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A recent study led to the development of a powerful epigenetic editing technology. The system unlocks the ability to precisely program chromatin modifications at any specific position in the genome, to understand their causal role in transcription regulation. This innovative approach will help to investigate the role of chromatin modifications in many biological processes, and to program desired gene activity responses, which may prove useful in disease settings.

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Chemists created an enzyme with boronic acid at its reactive center. This approach can produce more selective reactions with boron, and allows the use of directed evolution to improve its catalytic power.

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What determines the cycle life of batteries? And, more importantly, how can we extend it? An international research team has discovered that local disorder in the oxide cathode material increases the number of times Li-ion batteries can be charged and discharged.

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Scientists introduce a large language model-based AI system that revolutionizes chemistry by integrating 18 advanced tools for tasks like organic synthesis and drug discovery.

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Move over, graphene. There's a new, improved two-dimensional material in the lab. Borophene, the atomically thin version of boron first synthesized in 2015, is more conductive, thinner, lighter, stronger and more flexible than graphene, the 2D version of carbon. Now, researchers have made the material potentially more useful by imparting chirality -- or handedness -- on it, which could make for advanced sensors and implantable medical devices.

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A new computational model simulating fruit fly wing development has enabled researchers to identify previously hidden mechanisms behind organ generation. An research team developed a fruit fly model to reverse engineer the mechanisms that generate organ tissue.

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Researchers have found that herpesvirus infection modifies the structure and normal function of the mitochondria in the host cell. The new information will help to understand the interaction between herpesvirus and host cells. Knowledge can be utilized in the development of viral treatments.

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The earliest stages of mammalian embryo development are like an orchestra performance, where everyone must play at the exact right moment and in perfect harmony. New research identifies one of the conductors making sense of the chaos.

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In the ever-expanding search for energy resources, a new study has emerged from Mozambique's Maniamba Basin. Mozambique's Maniamba Basin could be a big source of natural gas.

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By using experimental electrochemical analyses, mass spectrometry, and computational quantum chemistry modeling, the researchers created an 'atomic-scale storyline' to explain how ozone is generated on NATO electrocatalysts. They identified that some of the nickel in NATO is probably leaching out of the electrodes via corrosion, and these nickel atoms, now floating in the solution near the catalyst, can promote chemical reactions that eventually generate ozone.

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In research that may be a step forward toward finding personalized treatments for Tourette disorder, scientists have bred mice that exhibit some of the same behaviors and brain abnormalities seen in humans with the disorder.