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Categories: Biology: Developmental, Paleontology: Fossils
Published New insights into the genetics of the common octopus: Genome at the chromosome level decoded
(via sciencedaily.com) Original source Octopuses are fascinating animals -- and serve as important model organisms in neuroscience, cognition research and developmental biology. To gain a deeper understanding of their biology and evolutionary history, validated data on the composition of their genome is needed, which has been lacking until now. Scientists have now been able to close this gap and, in a new study, determined impressive figures: 2.8 billion base pairs -- organized in 30 chromosomes. What sounds so simple is the result of complex, computer-assisted genome analyses and comparisons with the genomes of other cephalopod species.
Published Unlocking the secrets of cell behavior on soft substrates: A paradigm shift in mechanobiology
(via sciencedaily.com) Original source A research group has developed a new method for studying how cancer cells function in softer and stiffer tissue environments. This insight challenges the existing paradigm, opening up new possibilities for research in cancer biology and tissue engineering.
Published Extinct ape gets a facelift, 12 million years later
(via sciencedaily.com) Original source A new study has reconstructed the well-preserved but damaged skull of a great ape species that lived about 12 million years ago. The species, Pierolapithecus catalaunicus, may be crucial to understanding great ape and human evolution.
Published Scientists unveil detailed cell maps of the human brain and the nonhuman primate brain
(via sciencedaily.com) Original source A group of international scientists have mapped the genetic, cellular, and structural makeup of the human brain and the nonhuman primate brain. This understanding of brain structure allows for a deeper knowledge of the cellular basis of brain function and dysfunction, helping pave the way for a new generation of precision therapeutics for people with mental disorders and other disorders of the brain.
Published Extraordinary fossil find reveals details about the weight and diet of extinct saber-toothed marsupial
(via sciencedaily.com) Original source A 13-million-year-old saber-toothed marsupial skeleton discovered during paleontological explorations in Colombia is the most complete specimen recovered in the region.
Published Race to find world's oldest mammal fossils led to mud-slinging
(via sciencedaily.com) Original source The hunt for the world’s most ancient mammals descended into academic warfare in the seventies, researchers have discovered.
Published Researchers identify largest ever solar storm in ancient 14,300-year-old tree rings
(via sciencedaily.com) Original source An international team of scientists have discovered a huge spike in radiocarbon levels 14,300 years ago by analyzing ancient tree-rings found in the French Alps. The radiocarbon spike was caused by a massive solar storm, the biggest ever identified. A similar solar storm today would be catastrophic for modern technological society – potentially wiping out telecommunications and satellite systems, causing massive electricity grid blackouts, and costing us billions. The academics are warning of the importance of understanding such storms to protect our global communications and energy infrastructure for the future.
Published Ginger pigment molecules found in fossil frogs
(via sciencedaily.com) Palaeontologists discover molecular evidence of phaeomelanin, the pigment that produces ginger coloration. Phaeomelanin is now toxic to animals – this discovery may be first step in understand its evolution.
Published The end of genes: Routine test reveals unique divergence in genetic code
(via sciencedaily.com) Original source Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics. The genome of a protist has revealed a seemingly unique divergence in the DNA code signalling the end of a gene, suggesting the need for further research to better understand this group of diverse organisms.
Published New open-source method to improve decoding of single-cell data
(via sciencedaily.com) Original source Researchers have developed a new open-source computational method, dubbed Spectra, which improves the analysis of single-cell transcriptomic data. By guiding data analysis in a unique way, Spectra can offer new insights into the complex interplay between cells — like the interactions between cancer cells and immune cells, which are critical to improving immunotherapy treatments.
Published New type of tiny wasp comes with mysterious, cloud-like structures at ends of antennae
(via sciencedaily.com) Original source Fossil researchers have discovered a novel genus and species of tiny wasp with a mysterious, bulbous structure at the end of each antenna.
Published Avatars to help tailor glioblastoma therapies
(via sciencedaily.com) Original source Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study.
Published Scientists develop 3D printing method that shows promise for repairing brain injuries
(via sciencedaily.com) Original source Researchers have produced an engineered tissue representing a simplified cerebral cortex by 3D printing human stem cells. When implanted into mouse brain slices, the structures became integrated with the host tissue. The technique may ultimately be developed into tailored repairs to treat brain injuries.
Published When cells go boom: Study reveals inflammation-causing gene carried by millions
(via sciencedaily.com) Original source Researchers have found that a genetic change that increases the risk of inflammation, through a process described as ‘explosive’ cell death, is carried by up to 3% of the global population.
Published How new plant cell walls change their mechanical properties after cell division
(via sciencedaily.com) Original source Scientists reveal new plant cell walls can have significantly different mechanical properties compared to surrounding parental cell walls, enabling cells to change their local shape and influence the growth of plant organs.
Published Preventing spread of parasitic DNA in our genomes
(via sciencedaily.com) Original source Researchers have identified a new enzyme called PUCH, which plays a key role in preventing the spread of parasitic DNA in our genomes. These findings may reveal new insights into how our bodies detect and fight bacteria and viruses to prevent infections.
Published A hygiene program for chromosomes
(via sciencedaily.com) Original source Researchers identified and characterized a new cellular compartment in vertebrate cells that might be a precursor of today's eucaryotic nucleus. The study reveals that mammalian cells recognize, cluster, sort and keep extrachromosomal DNA -- like transfected plasmid DNA and endogenous circular DNAs originating from telomeres of the chromosome -- away from chromosomal DNA. That suggests that there is a cell autonomous genome defense system.
Published A more effective experimental design for engineering a cell into a new state
(via sciencedaily.com) Original source A new machine-learning approach helps scientists more efficiently identify the optimal intervention to achieve a certain outcome in a complex system, such as genome regulation, requiring far fewer experimental trials than other methods.
Published Researchers studied thousands of fertility attempts hoping to improve IVF
(via sciencedaily.com) Original source By genetically testing nearly one thousand embryos, scientists have provided the most detailed analysis of embryo fate following human in vitro fertilization.
Published Insights into early snake evolution through brain analysis
(via sciencedaily.com) Original source Recent study sheds new light on the enigmatic early evolution of snakes by examining an unexpected source: their brains. The results emphasize the significance of studying both the soft parts of animals’ bodies and their bones for understanding how animals evolved.