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Categories: Biology: Developmental, Paleontology: Fossils
Published Big boost for new epigenetics paradigm: CoRSIVs, first discovered in humans, now found in cattle



A study opens new possibilities to improve production efficiency in the cattle industry and potentially animal agriculture more broadly.
Published New ways to study spinal cord malformations in embryos



Scientists have successfully created mechanical force sensors directly in the developing brains and spinal cords of chicken embryos, which they hope will improve understanding and prevention of birth malformations such as spina bifida.
Published Muscle machine: How water controls the speed of muscle contraction



The flow of water within a muscle fiber may dictate how quickly muscle can contract, according to a new study.
Published Opening the right doors: 'Jumping gene' control mechanisms revealed



International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents the transcription of 'jumping genes.' DDM1 makes 'jumping genes' more accessible for transcription-suppressing chemical marks to be deposited. Because a variant of this protein exists in humans, the discovery provides insight into genetic conditions caused by such 'jumping gene' mutations.
Published First ever 3D reconstruction of 52,000-year-old woolly mammoth chromosomes thanks to serendipitously freeze-dried skin



An international research team has assembled the genome and 3D chromosomal structures of a 52,000-year-old woolly mammoth -- the first time such a feat has been achieved for any ancient DNA sample. The fossilized chromosomes, which are around a million times longer than most ancient DNA fragments, provide insight into how the mammoth's genome was organized within its living cells and which genes were active within the skin tissue from which the DNA was extracted. This unprecedented level of structural detail was retained because the mammoth underwent freeze-drying shortly after it died, which meant that its DNA was preserved in a glass-like state.
Published A new species of extinct crocodile relative rewrites life on the Triassic coastline



The surprising discovery of a new species of extinct crocodile relative from the Triassic Favret Formation of Nevada, USA, rewrites the story of life along the coasts during the first act of the Age of Dinosaurs. The new species Benggwigwishingasuchus eremicarminis reveals that while giant ichthyosaurs ruled the oceans, the ancient crocodile kin known as pseudosuchian archosaurs ruled the shores across the Middle Triassic globe between 247.2 and 237 million years ago.
Published Research reveals the most complete dinosaur discovered in the UK in a century



The most complete dinosaur discovered in the UK in the last 100 years, with a pubic hip bone the size of a 'dinner plate', has been described in a new article.
Published Phage-derived enzyme targets E. faecalis biofilms to mitigate acute graft-versus-host disease



Acute graft-versus-host disease occurs when donor immune cells attack the recipient's tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). Researchers recently identified a bacteriophage-derived enzyme called endolysin capable of targeting biofilms formed by Enterococcus faecalis. Their findings offer hope for tailored interventions in allo-HCT.
Published The plague may have caused the downfall of the Stone Age farmers



Ancient DNA from bones and teeth hints at a role of the plague in Stone Age population collapse. Contrary to previous beliefs, the plague may have diminished Europe's populations long before the major plague outbreaks of the Middle Ages, new research shows.
Published New one-step method to make multiple edits to a cell's genome



A team of scientists have developed a new method that enables them to make precise edits in multiple locations within a cell -- all at once. Using molecules called retrons, they created a tool that can efficiently modify DNA in bacteria, yeast, and human cells.
Published Ancient large kangaroo moved mainly on four legs, according to new research



A type of extinct kangaroo that lived during the Pleistocene around two and a half million to ten thousand years ago, known as the 'giant wallaby', was a poor hopper, a study has found.
Published Ancient dingo DNA shows modern dingoes share little ancestry with modern dog breeds



A study of ancient dingo DNA revealed that the distribution of modern dingoes across Australia, including those on K'gari (formerly Fraser Island), pre-dates European colonization and interventions like the dingo-proof fence.
Published Not so selfish after all: Viruses use freeloading genes as weapons



Certain pieces of DNA have been labeled as 'selfish genetic elements' due to notions that they don't contribute to a host organism's survival. Instead, researchers have now discovered that these elements have been weaponized and play a crucial role by cutting off a competitor's ability to reproduce.
Published Researchers uncover key mechanisms in chromosome structure development



Researchers are making strides in understanding how chromosome structures change throughout the cell's life cycle.
Published Giant salamander-like creature was a top predator in the ice age before the dinosaurs



Meet Gaiasia jennyae, the swamp creature with a toilet seat-shaped head. It lived 40 million years before the first dinosaurs, and it was the top predator in its ecosystem.
Published Extinct humans survived on the Tibetan plateau for 160,000 years



Bone remains found in a Tibetan cave 3,280 m above sea level indicate an ancient group of humans survived here for many millennia.
Published A new breakthrough in understanding regeneration in a marine worm



The sea worm Platynereis dumerilii is only a few centimeters long but has a remarkable ability: in just a few days, it can regenerate entire parts of its body after an injury or amputation. By focusing more specifically on the mechanisms at play in the regeneration of this worm's tail, a research team has observed that gut cells play a role in the regeneration of the intestine as well as other tissues such as muscle and epidermis.
Published Research shows how RNA 'junk' controls our genes



Researchers have made a significant advance in understanding how genes are controlled in living organisms. The new study focuses on critical snippets of RNA in the tiny, transparent roundworm Caenorhabditis elegans (C. elegans). The study provides a detailed map of the 3'UTR regions of RNA in C. elegans. 3'UTRs (untranslated regions) are segments of RNA involved in gene regulation.
Published Researchers thwart resistant bacteria's strategy



Bacteria are experts at evolving resistance to antibiotics. One resistance strategy is to cover their cell walls in sticky and gooey biofilm that antibiotics cannot penetrate. A new discovery could put a stop to this strategy.
Published Sixty-million-year-old grape seeds reveal how the death of the dinosaurs may have paved the way for grapes to spread



Scientists discovered the oldest fossil grapes in the Western Hemisphere, which help show how after the death of the dinosaurs, grapes spread across the world.