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Categories: Biology: Developmental, Paleontology: Climate

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A study has identified a protein complex that is activated by defects in the spliceosome, the molecular scissors that process genetic information. Future research could lead to new therapeutic approaches to treat diseases caused by faulty splicing.

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A new study provides the first evidence that the Arctic's frozen soil is the dominant force shaping Earth's northernmost rivers, confining them to smaller areas and shallower valleys than rivers to the south. But as climate change weakens Arctic permafrost, the researchers calculate that every 1 degree Celsius of global warming could release as much carbon as 35 million cars emit in a year as polar waterways expand and churn up the thawing soil.

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Many bacteria form an antibiotic-resistant slime. Research detailing that slime's structure could help lead to new treatments.

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The developmental regulators that confer the identity of N-fixing root nodules belong to a transcription factor family (LSH) more commonly associated with defining the shapes of stems, flowers and leaves.

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New research demonstrates a new class of hydrogels that can form not just outside cells, but also inside of them. These hydrogels exhibited similar mechanical properties both inside and outside of cells, providing researchers with a new tool to group proteins together inside of cells.

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Using a DNA-based delivery particle, researchers created a vaccine that can induce a strong antibody response against SARS-CoV-2.

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Researchers reveal a novel method to uncover bits of our genetic blueprint that come from ancient genetic parasites, offering fresh insights into human evolution and health.

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A team of researchers is delving deeper into the science behind how spiny mice can regenerate lost tissue and using what they learn to trigger regeneration in other types of mice -- advances which one day may be translated into humans. Whereas adult laboratory mice heal injuries with scar tissue, spiny mice have the unique ability to regrow lost skin and regenerate musculoskeletal tissues in their body.

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Researchers were able to control the growth of thin, branching networks that support cellular structure and help cells function. The networks, called microtubules, can exert force and precisely transport chemicals at a subcellular level.

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Antiretroviral therapy (ART) does an excellent job at suppressing HIV to undetectable levels in the blood. However, small amounts of latent virus hide throughout the body, and when treatment is stopped, it opens the door for the virus to rebound. Researchers identified which tissues SIV, the nonhuman primate version of HIV, reemerges from first, just seven days after ART is stopped.

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Scientists have succeeded in achieving the world's first pregnancy of a rhinoceros after an embryo transfer. The southern white rhino embryo was produced in vitro from collected egg cells and sperm and transferred into a southern white rhino surrogate mother at the Ol Pejeta Conservancy in Kenya on September 24, 2023. The BioRescue team confirmed a pregnancy of 70 days with a well-developed 6.4 cm long male embryo. The successful embryo transfer and pregnancy are a proof of concept and allow to now safely move to the transfer of northern white rhino embryos -- a cornerstone in the mission to save the northern white rhino from extinction.

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The brown bear is one of the largest living terrestrial carnivores, and is widely distributed across the Northern Hemisphere. Unlike many other large carnivores that went extinct at the end of the last Ice Age (cave bear, sabretoothed cats, cave hyena), the brown bear is one of the lucky survivors that made it through to the present. The question has puzzled biologists for close to a century -- how was this so?

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A new method predicts how much flooding a coastal community is likely to experience as hurricanes evolve due to climate change. Using New York as a test case, the model predicts Hurricane Sandy-level flooding will occur roughly every 30 years by 2099.

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Researchers showed that the way in which genes are turned on and off as bacteria grow provide clues to their regulation.

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A new way to measure the ocean oxygen level and its connections with carbon dioxide in the Earth's atmosphere during the last ice age could help explain the role oceans played in past glacial melting cycles and improve predictions of how ocean carbon cycles will respond to global warming.

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Researchers have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way. The result opens new avenues for understanding how the Notch signalling pathway works and how it is involved in several serious diseases.

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The new theoretical research proposes that animal size over time depends on two key ecological factors.

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Southern Africa contains the vast majority of the world's remaining populations of both black and white rhinoceroses (80% and 92%, respectively). The region's climate is changing rapidly as a result global warming. Traditional conservation efforts aimed at protecting rhinos have focused on poaching, but until now, there has been no analysis of the impact that climate change may have on the animals. A research team has recently reported that, though the area will be affected by both higher temperatures and changing precipitation, the rhinos are more sensitive to rising temperatures, which will quickly increase above the animals' acceptable maximum threshold.

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To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.

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A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.