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Categories: Biology: Developmental, Offbeat: Computers and Math
Published New ways to study spinal cord malformations in embryos
(via sciencedaily.com) Original source Scientists have successfully created mechanical force sensors directly in the developing brains and spinal cords of chicken embryos, which they hope will improve understanding and prevention of birth malformations such as spina bifida.
Published Neural networks made of light
(via sciencedaily.com) Original source Scientists propose a new way of implementing a neural network with an optical system which could make machine learning more sustainable in the future. In a new paper, the researchers have demonstrated a method much simpler than previous approaches.
Published Muscle machine: How water controls the speed of muscle contraction
(via sciencedaily.com) Original source The flow of water within a muscle fiber may dictate how quickly muscle can contract, according to a new study.
Published Learning dance moves could help humanoid robots work better with humans
(via sciencedaily.com) Original source Engineers have trained a humanoid robot to perform a variety of expressive movements, from simple dance routines to gestures like waving, high-fiving and hugging, all while maintaining a steady gait on diverse terrains. This work marks a step towards building robots that perform more complex and human-like motions.
Published Opening the right doors: 'Jumping gene' control mechanisms revealed
(via sciencedaily.com) Original source International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents the transcription of 'jumping genes.' DDM1 makes 'jumping genes' more accessible for transcription-suppressing chemical marks to be deposited. Because a variant of this protein exists in humans, the discovery provides insight into genetic conditions caused by such 'jumping gene' mutations.
Published First ever 3D reconstruction of 52,000-year-old woolly mammoth chromosomes thanks to serendipitously freeze-dried skin
(via sciencedaily.com) Original source An international research team has assembled the genome and 3D chromosomal structures of a 52,000-year-old woolly mammoth -- the first time such a feat has been achieved for any ancient DNA sample. The fossilized chromosomes, which are around a million times longer than most ancient DNA fragments, provide insight into how the mammoth's genome was organized within its living cells and which genes were active within the skin tissue from which the DNA was extracted. This unprecedented level of structural detail was retained because the mammoth underwent freeze-drying shortly after it died, which meant that its DNA was preserved in a glass-like state.
Published A new twist on artificial 'muscles' for safer, softer robots
(via sciencedaily.com) Original source Engineers have developed a new soft, flexible device that makes robots move by expanding and contracting -- just like a human muscle. To demonstrate their new device, called an actuator, the researchers used it to create a cylindrical, worm-like soft robot and an artificial bicep. In experiments, the cylindrical soft robot navigated the tight, hairpin curves of a narrow pipe-like environment, and the bicep was able to lift a 500-gram weight 5,000 times in a row without failing.
Published Phage-derived enzyme targets E. faecalis biofilms to mitigate acute graft-versus-host disease
(via sciencedaily.com) Original source Acute graft-versus-host disease occurs when donor immune cells attack the recipient's tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). Researchers recently identified a bacteriophage-derived enzyme called endolysin capable of targeting biofilms formed by Enterococcus faecalis. Their findings offer hope for tailored interventions in allo-HCT.
Published New one-step method to make multiple edits to a cell's genome
(via sciencedaily.com) Original source A team of scientists have developed a new method that enables them to make precise edits in multiple locations within a cell -- all at once. Using molecules called retrons, they created a tool that can efficiently modify DNA in bacteria, yeast, and human cells.
Published Not so selfish after all: Viruses use freeloading genes as weapons
(via sciencedaily.com) Original source Certain pieces of DNA have been labeled as 'selfish genetic elements' due to notions that they don't contribute to a host organism's survival. Instead, researchers have now discovered that these elements have been weaponized and play a crucial role by cutting off a competitor's ability to reproduce.
Published Researchers uncover key mechanisms in chromosome structure development
(via sciencedaily.com) Original source Researchers are making strides in understanding how chromosome structures change throughout the cell's life cycle.
Published A new breakthrough in understanding regeneration in a marine worm
(via sciencedaily.com) Original source The sea worm Platynereis dumerilii is only a few centimeters long but has a remarkable ability: in just a few days, it can regenerate entire parts of its body after an injury or amputation. By focusing more specifically on the mechanisms at play in the regeneration of this worm's tail, a research team has observed that gut cells play a role in the regeneration of the intestine as well as other tissues such as muscle and epidermis.
Published Research shows how RNA 'junk' controls our genes
(via sciencedaily.com) Original source Researchers have made a significant advance in understanding how genes are controlled in living organisms. The new study focuses on critical snippets of RNA in the tiny, transparent roundworm Caenorhabditis elegans (C. elegans). The study provides a detailed map of the 3'UTR regions of RNA in C. elegans. 3'UTRs (untranslated regions) are segments of RNA involved in gene regulation.
Published New and improved camera inspired by the human eye
(via sciencedaily.com) Original source Computer scientists have invented a camera mechanism that improves how robots see and react to the world around them. Inspired by how the human eye works, their innovative camera system mimics the tiny involuntary movements used by the eye to maintain clear and stable vision over time.
Published Researchers thwart resistant bacteria's strategy
(via sciencedaily.com) Original source Bacteria are experts at evolving resistance to antibiotics. One resistance strategy is to cover their cell walls in sticky and gooey biofilm that antibiotics cannot penetrate. A new discovery could put a stop to this strategy.
Published 'World record' for data transmission speed
(via sciencedaily.com) Original source Researchers have sent data at a record rate of 402 terabits per second using commercially available optical fiber. This beats their previous record, announced in March 2024, of 301 terabits or 301,000,000 megabits per second using a single, standard optical fiber.
Published Soft, stretchy electrode simulates touch sensations using electrical signals
(via sciencedaily.com) Original source A team of researchers has developed a soft, stretchy electronic device capable of simulating the feeling of pressure or vibration when worn on the skin. This device represents a step towards creating haptic technologies that can reproduce a more varied and realistic range of touch sensations for applications such as virtual reality, medical prosthetics and wearable technology.
Published New, holistic way to teach synthetic biology
(via sciencedaily.com) Original source Synthetic biology combines principles from science, engineering and social science, creating emerging technologies such as alternative meats and mRNA vaccines; Deconstructing synthetic biology across scales gives rise to new approach to uniting traditional disciplines; Case studies offer a modular, accessible approach to teaching at different institutions.
Published From takeoff to flight, the wiring of a fly's nervous system is mapped
(via sciencedaily.com) Original source Although a fly's motor neurons are few, it performs remarkable aerial and terrestrial feats. A wiring diagram recently created of the motor circuits in the central nervous system of the fruit fly is providing detailed information on how the nerve coordination of leg movements differs from that controlling the wings. Such studies reveal the unexpected complexity of the fly's tiny motor system. They also advance the understanding of how the central nervous system in animals coordinates individual muscles to carry out a variety of behaviors.
Published Cell division: Before commitment, a very long engagement
(via sciencedaily.com) Original source Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours -- sometimes more than a day -- in a reversible intermediate state, according to a new discovery. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.