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Published

CRISPR-based genome editing in Nile grass rats      (via sciencedaily.com)     Original source 

A team of researchers has discovered a set of methods that enabled the first successful CRISPR-based genome editing in Nile grass rats.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Microbiology Biology: Zoology Environmental: Water Offbeat: Earth and Climate Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals
Published

Creature the size of a dust grain found hiding in California's Mono Lake      (via sciencedaily.com)     Original source 

Mono Lake is a beautiful but harsh environment, its salty and arsenic-laced water home to brine shrimp, alkali flies and little else. Scientists recently discovered an unsuspected resident, however, a microscopic creature -- a choanoflagelatte -- that forms colonies that harbor their own unique bacterial microbiomes. The creature, part of the sister group to all animals, could shed light on the evolution of animals' intimate interactions with bacteria and the rise of multicellular life.

Biology: Biochemistry Biology: Developmental Biology: General
Published

T cells manipulate the memory of innate immune cells      (via sciencedaily.com)     Original source 

Research reveals that T cells from the adaptive immune system can manipulate the memory of innate immune cells. Previously, it was believed that the memory of innate immune cells operated independently. This surprising connection opens up new possibilities for the treatment of various diseases. A mouse model shows that no immunosuppressive drugs are needed after an organ transplantation if this interaction between T cells and the innate immunity is temporarily blocked after the transplantation.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Benefits and downside of fasting      (via sciencedaily.com)     Original source 

Researchers identified a signaling pathway in mice that boosts intestinal stem cells' regeneration abilities after fasting. When cancerous mutations occurred during this regenerative period, mice were more likely to develop early-stage intestinal tumors.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Ecology: Endangered Species Ecology: Nature Offbeat: General Offbeat: Plants and Animals
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Researchers uncover the secrets of 'plant puberty'      (via sciencedaily.com)     Original source 

Researchers have identified the genetic changes linked to why plants go through a developmental change similar to 'puberty' at different rates, a discovery which could lead to better crop nutrition.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Biology: Zoology Offbeat: General Offbeat: Plants and Animals
Published

Searching old stem cells that stay young forever      (via sciencedaily.com)     Original source 

The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists have now identified possible candidates for multipotent stem cells in the sea anemone for the first time. These stem cells are regulated by evolutionary highly conserved genes.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

Zebrafish use surprising strategy to regrow spinal cord      (via sciencedaily.com)     Original source 

A new study maps out a detailed atlas of all the cells involved in regenerating the zebrafish spinal cord. In an unexpected finding, the researchers showed that survival and adaptability of the severed neurons themselves is required for full spinal cord regeneration. Surprisingly, the study showed that stem cells capable of forming new neurons play a complementary role but don t lead the process.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Microbiology
Published

Scientists map DNA of Lyme disease bacteria      (via sciencedaily.com)     Original source 

Researchers have produced a genetic analysis of Lyme disease bacteria that may pave the way for improved diagnosis, treatment, and prevention of the tick-borne ailment.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: General
Published

New way inflammation impacts cell communication      (via sciencedaily.com)     Original source 

Researchers have made significant progress in understanding how cells communicate during inflammation.

Biology: Cell Biology Biology: Developmental Biology: General
Published

Common equine painkiller disrupts assisted reproduction technique efficiency in mares      (via sciencedaily.com)     Original source 

Researchers have discovered that phenylbutazone, a non-steroidal anti-inflammatory drug (NSAID) commonly prescribed in horses, can affect the ability of a mare's egg cells -- called 'oocytes' -- to become viable embryos, which is a crucial step in assisted reproduction in horses.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

Exciting advance in stem cell therapy      (via sciencedaily.com)     Original source 

A new technique for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Biology: Zoology Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals
Published

Rewriting the evolutionary history of critical components of the nervous system      (via sciencedaily.com)     Original source 

A new study has rewritten the conventionally understood evolutionary history of certain ion channels -- proteins critical for electrical signaling in the nervous system. The study shows that the Shaker family of ion channels were present in microscopic single cell organisms well before the common ancestor of all animals and thus before the origin of the nervous system.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

Starvation and adhesion drive formation of keratinocyte patterns in skin      (via sciencedaily.com)     Original source 

Cell-cell adhesion-induced patterning in keratinocytes can be explained by just starvation and strong adhesion researchers find.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Physics: General
Published

How mortal filaments' self-assemble and maintain order: Align or die      (via sciencedaily.com)     Original source 

A previously unknown mechanism of active matter self-organization essential for bacterial cell division follows the motto 'dying to align': Misaligned filaments 'die' spontaneously to form a ring structure at the center of the dividing cell. The work could find applications in developing synthetic self-healing materials.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Microbiology Biology: Molecular Biology: Zoology
Published

A new mechanism for shaping animal tissues      (via sciencedaily.com)     Original source 

A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development. Research teams have now found a mechanism by which tissues can be 'programmed' to transition from a flat state to a three-dimensional shape.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Bacteria encode hidden genes outside their genome--do we?      (via sciencedaily.com)     Original source 

A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies.

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Published

Researchers make breakthrough in understanding species abundance      (via sciencedaily.com)     Original source 

The key finding was that temperature and genome size, not body size, had the greatest influence on the maximum population growth rate of the diatoms. Yet body size still mattered in colder latitudes, conserving Bermann's Rule.