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Categories: Biology: Zoology, Engineering: Robotics Research
Published A shortcut for drug discovery
(via sciencedaily.com) Original source For most human proteins, there are no small molecules known to bind them chemically (so called 'ligands'). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel medicines. Researchers at CeMM, in a collaboration with Pfizer, have now leveraged and scaled a method to measure the binding activity of hundreds of small molecules against thousands of human proteins. This large-scale study revealed tens of thousands of ligand-protein interactions that can now be explored for the development of chemical tools and therapeutics. Moreover, powered by machine learning and artificial intelligence, it allows unbiased predictions of how small molecules interact with all proteins present in living human cells. These groundbreaking results have been published in the journal Science (DOI: 10.1126/science.adk5864), and all generated data and models are freely available for the scientific community.
Published Curiosity promotes biodiversity
(via sciencedaily.com) Original source Cichlid fishes exhibit differing degrees of curiosity. The cause for this lies in their genes, as reported by researchers. This trait influences the cichlids' ability to adapt to new habitats.
Published Herring arrives earlier in the Wadden Sea due to climate change
(via sciencedaily.com) Original source Due to the changing climate, young herring arrive in the Wadden Sea earlier and earlier in spring.
Published Scientists replace fishmeal in aquaculture with microbial protein derived from soybean processing wastewater
(via sciencedaily.com) Original source Scientists have successfully replaced half of the fishmeal protein in the diets of farmed Asian seabass with a 'single cell protein' cultivated from microbes in soybean processing wastewater, paving the way for more sustainable fish farming practices.
Published How do birds flock? Researchers do the math to reveal previously unknown aerodynamic phenomenon
(via sciencedaily.com) Original source How do birds fly in a coordinated and seemingly effortless fashion? Part of the answer lies in precise, and previously unknown, aerodynamic interactions, reports a team of mathematicians. Its breakthrough broadens our understanding of wildlife, including fish, who move in schools, and could have applications in transportation and energy.
Published Unveiling the lionfish invasion in the Mediterranean Sea
(via sciencedaily.com) Original source Researchers have published a comprehensive study on the invasion of lionfish in the Mediterranean Sea, highlighting a rapid spread and the potential ecological impacts. The research shows the lionfish species Pterois miles has significantly expanded its territory in the Mediterranean since the invasion began around ten years ago. The invasive species has established presence in the eastern Mediterranean, with observations now extending to colder waters previously thought to be unsuitable for the species.
Published Color variants in cuckoos: The advantages of rareness
(via sciencedaily.com) Original source Every cuckoo is an adopted child -- raised by foster parents, into whose nest the cuckoo mother smuggled her egg. The cuckoo mother is aided in this subterfuge by her resemblance to a bird of prey. There are two variants of female cuckoos: a gray morph that looks like a sparrowhawk, and a rufous morph. Male cuckoos are always gray.
Published Why can't robots outrun animals?
(via sciencedaily.com) Original source Robotics engineers have worked for decades and invested many millions of research dollars in attempts to create a robot that can walk or run as well as an animal. And yet, it remains the case that many animals are capable of feats that would be impossible for robots that exist today.
Published Zebra finch chicks don't babble for no reason
(via sciencedaily.com) Original source Their first vocalizations help young zebra finch males to memorize the songs of adults.
Published Squids' birthday influences mating
(via sciencedaily.com) Original source The day a male spear squid hatches determines which mating tactic he will use throughout his life, according to new research. Spear squid (Heterololigo bleekeri) that hatch earlier in the season become 'consorts' which fight for mating opportunities. Those which hatch later become 'sneakers,' which use more clandestine mating tactics. Researchers found that the mating tactic determined by the birth date was fixed for the squid's whole life. Understanding how mating tactics are influenced by birth date, and the environmental conditions at that time, can help researchers consider how squid might be affected by climate change and the implications for marine resource management.
Published Study compares salmonella rates in backyard, commercial poultry farm samples
(via sciencedaily.com) Original source Researchers find less Salmonella on backyard poultry farms. But concerns remain about the prevalance of multidrug-resistant bacteria on both large and small farms.
Published Tropical fish are invading Australian ocean water
(via sciencedaily.com) Original source A study of shallow-water fish communities on rocky reefs in south-eastern Australia has found climate change is helping tropical fish species invade temperate Australian waters.
Published New compound from blessed thistle promotes functional nerve regeneration
(via sciencedaily.com) Original source Blessed thistle (Cnicus benedictus) is a plant in the family Asteraceae. For centuries, it has been used as a medicinal herb as an extract or tea, e.g. to aid the digestive system. Researchers have now found a completely novel use for Cnicin. Animal models as well as human cells have shown that Cnicin significantly accelerates axon (nerve fibers) growth.
Published 'Itinerant breeding' in East Coast shorebird species
(via sciencedaily.com) Original source A study has found direct evidence of a species -- the American woodcock, a migratory shorebird from eastern and central North America -- that overlaps periods of migration and reproduction, a rare breeding strategy known as 'itinerant breeding.'
Published Lemur's lament: When one vulnerable species stalks another
(via sciencedaily.com) Original source What can be done when one threatened animal kills another? Scientists studying critically endangered lemurs in Madagascar confronted this difficult reality when they witnessed attacks on lemurs by another vulnerable species, a carnivore called a fosa.
Published Key protein regulates immune response to viruses in mammal cells
(via sciencedaily.com) Original source Researchers have revealed the regulatory mechanism of a specific protein, TRBP, that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and nucleic acid medicines to treat genetic disorders.
Published Helping migrating salmon survive mortality hot-spot
(via sciencedaily.com) Original source Researchers used acoustic telemetry to tag and track coho on their journey.
Published Why can zebrafish regenerate damaged heart tissue, while other fish species cannot?
(via sciencedaily.com) Original source A heart attack will leave a permanent scar on a human heart, yet other animals, including zebrafish, can clear cardiac scar tissue and regrow damaged muscle as adults. Biologists sheds new light on how zebrafish heal heart tissue by comparing how this species responds to heart injury with medaka, a fish species that cannot regenerate cardiac tissue.
Published Octopus inspires new suction mechanism for robots
(via sciencedaily.com) Original source A new robotic suction cup which can grasp rough, curved and heavy stone, has been developed by scientists.
Published Fourteen years after the Gulf of Mexico oil spill, endemic fishes face an uncertain future
(via sciencedaily.com) Original source The 2010 Gulf of Mexico Deepwater Horizon oil spill, the largest accidental spill in history, released almost 100 million gallons of oil, causing significant pollution. A decade later, its long-term effects remain unclear. A study investigating the impact on endemic fish species found 29 of 78 species unreported in museum collections since the spill, suggesting potential loss of biodiversity.