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Categories: Biology: Biochemistry, Chemistry: Inorganic Chemistry
Published Researchers teaching artificial intelligence about frustration in protein folding
(via sciencedaily.com) Original source Scientists have found a new way to predict how proteins change their shape when they function, which is important for understanding how they work in living systems. While recent artificial intelligence (AI) technology has made it possible to predict what proteins look like in their resting state, figuring out how they move is still challenging because there is not enough direct data from experiments on protein motions to train the neural networks.
Published Humpbacks are among animals who manufacture and wield tools
(via sciencedaily.com) Original source Researchers suggest a new designation of the humpback whales they study: tool wielders. Researchers have known that humpback whales create "bubble-nets" to hunt, but they have learned that the animals don't just create the bubble-nets; they manipulate this unique tool in a variety of ways to maximize their food intake in Alaskan feeding grounds.
Published Hospital bacteria tracked better than ever before with new technique
(via sciencedaily.com) Original source New method provides high-resolution surveillance data about multiple common antibiotic-resistant bacteria at once and could help prevent the spread of infections.
Published Mother's gut microbiome during pregnancy shapes baby's brain development
(via sciencedaily.com) Original source A study in mice has found that the bacteria Bifidobacterium breve in the mother's gut during pregnancy supports healthy brain development in the fetus.
Published How early-life antibiotics turn immunity into allergy
(via sciencedaily.com) Original source Researchers have shown how and why the depletion of microbes in a newborn's gut by antibiotics can lead to lifelong respiratory allergies. The research team identified a specific cascade of events that lead to allergies and asthma, opening many new avenues for exploring potential preventions and treatments.
Published 'Masters of shape-shifting': How darkling beetles conquered the world
(via sciencedaily.com) Original source Large-scale genomic analysis of darkling beetles, a hyper-diverse insect group of more than 30,000 species worldwide, rolls back the curtain on a 150-million-year evolutionary tale of one of Earth's most ecologically important yet inconspicuous creatures, according to new research.
Published New worm study paves way for better RNA-based drugs to treat human disease
(via sciencedaily.com) Original source Researchers have discovered RNA mechanisms that may lead to more effective, durable and targeted treatments for conditions like high cholesterol, liver diseases and cancers.
Published Deadly sea snail toxin could be key to making better medicines
(via sciencedaily.com) Original source Scientists are finding clues for how to treat diabetes and hormone disorders in an unexpected place: a toxin from one of the most venomous animals on the planet.
Published 'Molecular compass' points way to reduction of animal testing
(via sciencedaily.com) Original source Machine learning models have become increasingly popular for risk assessment of chemical compounds. However, they are often considered 'black boxes' due to their lack of transparency. To increase confidence in these models, researchers proposed carefully identifying the areas of chemical space where these models are weak. They developed an innovative software tool for this purpose, and the results of this research approach have just been published.
Published A new reaction to enhance aromatic ketone use in chemical synthesis
(via sciencedaily.com) Original source Researchers develop a one pot process to transform aromatic ketones to esters, offering advancements in pharmaceutical synthesis and materials science.
Published Investigating the interplay of folding and aggregation in supramolecular polymer systems
(via sciencedaily.com) Original source Scientists have developed photoresponsive supramolecular polymers that can undergo both intrachain folding and interchain aggregation.
Published Adaptive 3D printing system to pick and place bugs and other organisms
(via sciencedaily.com) Original source A new adaptive 3D printing system can identify the positions of randomly distributed organisms and safely move them to specific locations for assembly.
Published Scientists discover new code governing gene activity
(via sciencedaily.com) Original source A newly discovered code within DNA -- coined 'spatial grammar' -- holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated hidden spatial grammar embedded in DNA. The research could reshape scientists' understanding of gene regulation and how genetic variations may influence gene expression in development or disease.
Published Researchers uncover the secrets of 'plant puberty'
(via sciencedaily.com) Original source Researchers have identified the genetic changes linked to why plants go through a developmental change similar to 'puberty' at different rates, a discovery which could lead to better crop nutrition.
Published Gut microbial pathway identified as target for improved heart disease treatment
(via sciencedaily.com) Original source Researchers have made a significant discovery about how the gut microbiome interacts with cells to cause cardiovascular disease. The study found phenylacetylglutamine (PAG), produced by gut bacteria as a waste product, then absorbed and formed in the liver, interacts with previously undiscovered locations on beta-2 adrenergic receptors on heart cells once it enters the circulation.
Published Using AI to find the polymers of the future
(via sciencedaily.com) Original source Finding the next groundbreaking polymer is always a challenge, but now researchers are using artificial intelligence (AI) to shape and transform the future of the field.
Published Researchers develop an instant version of trendy, golden turmeric milk
(via sciencedaily.com) Original source If you've visited a trendy cafe in the past few years, you might have noticed 'golden' turmeric milk on the menu. This fancy drink is caffeine-free, coffee-free and can even be vegan. And now, researchers have developed an efficient method to make a powdered, plant-based, instant version that maintains the beneficial properties of the ingredients while also extending its shelf life.
Published Peering into the mind of artificial intelligence to make better antibiotics
(via sciencedaily.com) Original source Artificial intelligence (AI) has exploded in popularity as of late. But just like a human, it's hard to read an AI model's mind. Explainable AI (XAI) could help us do just that by providing justification for a model's decisions. And now, researchers are using XAI to scrutinize predictive AI models more closely, which could help make better antibiotics.
Published Evidence stacks up for poisonous books containing toxic dyes
(via sciencedaily.com) Original source Some of the attractive hues of brightly colored, cloth-bound books from the Victorian era come from dyes that could pose a health risk to readers, collectors or librarians. The latest research on these 'poison books' used three techniques -- including one that hasn't previously been applied to books -- to assess dangerous dyes in a university collection and found some volumes had levels that might be unsafe.
Published Researchers develop index to quantify circular bioeconomy
(via sciencedaily.com) Original source As the world faces the challenges of mitigating climate change and providing resources for a growing population, there is increasing focus on developing circular economies for sustainable production. But to evaluate strategies and impacts, it is necessary to have reliable metrics. Researchers have now developed a Circularity Index that provides a comprehensive method to quantify circularity in bioeconomic systems. In a new paper, they outline the method and apply it to two case studies -- a corn/soybean farming operation and the entire U.S. food and agriculture system.