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Categories: Biology: Biochemistry, Space: Astrophysics

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Researchers have rediscovered and successfully cultivating Rhabdamoeba marina -- a rare marine amoeba that has only been reported in two cases in the past century. Using this culture strain, they performed a comprehensive analysis of its genetic sequence, revealing for the first time the phylogenetic position of this enigmatic amoeba, and proposed a novel taxonomic classification based on their research findings.

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Researchers have discovered a 'genomic tug of war' in animal studies that could influence how well certain patients -- or certain cancers -- respond to decitabine, a drug used to treat myelodysplastic syndromes that is plagued by drug resistance issues. For the first time, researchers show that decitabine causes coding and non-coding regions of DNA to engage in a tug of war for a gene activator, called H2A.Z. Typically, deticabine draws this gene activator away from coding DNA, causing gene expression to grind to a halt and cells to die. However, many types of cancer have very high levels of H2A.Z, which may help them overcome this decitabine-induced tug of war, allowing the cancer to grow.

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A new theoretical model helps explain how epigenetic memories, encoded in chemical modifications of chromatin, are passed from generation to generation.  Within each cell's nucleus, researchers suggest, the 3D folding patterns of its genome determines which parts of the genome will be marked by these chemical modifications.

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Researchers take a look at data that has so far been mostly discarded as contamination, revealing the previously underestimated role of extracellular vesicles (EVs). These are important for the exchange of genetic information between cells and thus for the microbial community in the sea.

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New research has revealed that bumblebees cannot taste pesticides present in nectar, even at lethal concentrations. This means bumblebees are not able to avoid contaminated nectar, putting them at high risk of pesticide exposure and posing a threat to crop pollination.

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The internal clocks of grizzly bears appear to keep ticking through hibernation, according to a genetic study. This persistence highlights the strong role of circadian rhythms in the metabolism of many organisms including humans. The genetic study confirmed observational evidence that bears' energy production still waxes and wanes in a daily pattern even as they slumber for several months without eating. The researchers also found that during hibernation the amplitude of the energy production was blunted, meaning the range of highs and lows was reduced. The peak also occurred later in the day under hibernation than during the active season, but the daily fluctuation was still there. 

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Human trade and transport have led to the intentional and accidental introductions of non-native species outside of their natural range globally. These biological invasions can cause extinctions, cost trillions, and spread diseases. A study has investigated how many of these non-native species already exist worldwide and which species groups are particularly prone to become non-native.

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Researchers have discovered previously unknown changes in a specific type of liver cells, potentially opening avenues for a new treatment for liver fibrosis, a potentially life-threatening condition. Currently, there are no drugs available to treat liver fibrosis.

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Many mammals, from domestic cats and dogs to giant pandas, use scent to communicate with each other. A new study shows how domestic cats send signals to each other using odors derived from families of bacteria living in their anal glands. 

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Social distancing when sick has become second nature to many of us in the past few years, but some sick animals appear to take a different approach. A new study of house finches uncovered a surprising result. Unlike other social animals who passively or actively isolate themselves when sick, this gregarious backyard bird species gravitates toward healthy flock mates when they are sick, even more so than healthy birds do.

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Cannabinoids, naturally occurring compounds found in hemp plants, may have evolved to deter pests from chewing on them, according to new research that showed higher cannabinoid concentrations in hemp leaves led to proportionately less damage from insect larvae.

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Bacteria have an array of strategies to counter viral invasion, but how they first spot a stranger in their midst has long been a mystery.

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ALMA (Atacama Large Millimeter/submillimeter Array) has demonstrated the highest resolution yet with observations of an old star. The observations show that the star is surrounded by a ring-like structure of gas and that gas from the star is escaping to the surrounding space. Future observations with the newly demonstrated high resolution are expected to elucidate, not only the end of a star's life, but also the beginning, when planets are still forming.

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Recently, morning omelets and holiday dinners have gotten more expensive. One likely cause is bird flu, outbreaks of which led to the deaths of millions of chickens and turkeys from infection or culling in 2022, according to the U.S. Department of Agriculture, and which still demands rigorous monitoring of wild populations. Now, researchers have developed a method that detected infectious bird flu virus in wetlands frequented by waterfowl.

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Researchers discover how ribosomes contribute to the recognition and removal of RNA crosslinking damage.

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An unexpected genetic discovery in wheat has led to opportunities for metabolic engineering of versatile compounds with potential to improve its nutritional qualities and resilience to disease.

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A genetic breakthrough has opened new opportunities for iron-fortified vegetables and cereal crops to help address the global health issue of anemia.

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After a distant star's explosive death, an active stellar corpse was the likely source of repeated energetic flares observed over several months -- a phenomenon astronomers had never seen before, astronomers report.

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Newly discovered iron storage 'ferrosomes' inside the bacterium C. diff -- the leading cause of hospital-acquired infections -- are important for infection in an animal model and could offer new targets for antibacterial drugs. They also represent a rare demonstration of a membrane-bound structure inside a pathogenic bacterium, upsetting the biological dogma that bacteria do not contain organelles. 

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Researchers have developed a new deep learning AI tool that generates life-like birdsongs to train bird identification tools, helping ecologists to monitor rare species in the wild.