Showing 20 articles starting at article 1461
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Categories: Biology: Biochemistry, Environmental: Water
Published New system triggers cellular waste disposal
(via sciencedaily.com) Original source Established treatments for cancer and other diseases often focus on inhibiting harmful enzymes to mitigate their effects. However, a more innovative approach has emerged: harnessing the cell's natural waste disposal system not just to deactivate but to entirely eradicate these proteins. Researchers have previously demonstrated the efficacy of this approach through two distinct methods. Now they unveil a third system capable of targeting and disposing of previously inaccessible proteins.
Published Detecting pathogens faster and more accurately by melting DNA
(via sciencedaily.com) Original source A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.
Published 'The future is fungal': New research finds that fungi that live in healthy plants are sensitive to climate change
(via sciencedaily.com) Original source Findings more than a decade in the making reveal a rich diversity of beneficial fungi living in boreal forest trees, with implications for the health of forests.
Published Low oxygen in lakes may breathe new life into conservation efforts for water quality
(via sciencedaily.com) Original source An international team analyzed 656 lakes across five continents to provide empirical evidence supporting a long-held theory regarding low deep-water oxygen concentrations, or anoxia.
Published Engineering a coating for disease-free produce
(via sciencedaily.com) Original source Texas A&M researchers combine food-grade wax with essential oils to defend produce from bacteria.
Published Gulf corals still suffering more than a decade after Deepwater Horizon oil spill, scientists report
(via sciencedaily.com) Original source Deep-water corals in the Gulf of Mexico are still struggling to recover from the devastating Deepwater Horizon oil spill in 2010, scientists report at the Ocean Science Meeting in New Orleans. Comparing images of more than 300 corals over 13 years -- the longest time series of deep-sea corals to date -- reveals that in some areas, coral health continues to decline to this day.
Published Bridging diet, microbes, and metabolism: Implications for metabolic disorders
(via sciencedaily.com) Original source Mounting evidence suggests that the secret to understanding human health and combating metabolic diseases lies hidden within the microscopic world of our gut bacteria. Recent research reveals that a specific fatty acid produced by gut bacteria directly influences fat metabolism in animals. This research is pivotal as it sheds light on the complex interplay between the diet, gut microbiota, and host metabolic health, offering insights that could open new avenues in our approach to managing metabolic disorders.
Published Giant new snake species identified in the Amazon
(via sciencedaily.com) Original source A team of scientists on location with a film crew in the remote Amazon has uncovered a previously undocumented species of giant anaconda.
Published Photosynthetic mechanism of purple sulfur bacterium adapted to low-calcium environments
(via sciencedaily.com) Original source Purple sulfur bacteria (PSB) convert light energy into chemical energy through photosynthesis. Interestingly, certain species can photosynthesize even in environments with low-calcium levels. Using cryo-electron microscopy, researchers unveiled the structure of light-harvesting complexes and elucidated the mechanism that facilitates photosynthesis under low-calcium conditions.
Published Breakthrough in developing the PD-1-enhanced DNA vaccine for over 6-year cART-free AIDS prevention and virologic control
(via sciencedaily.com) Original source Researchers found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model. The vaccinated monkeys remained free of AIDS for six years and achieved virologic control without the need for combination antiretroviral therapy (cART), a treatment used to suppress viral replication in individuals living with human immunodeficiency virus (HIV). The study also found that polyfunctional and broadly reactive effector-memory virus-specific T cells were maintained in the protected experimental macaques for over six years. The findings provide supporting evidence that the PD-1-enhanced DNA vaccine strategy holds promise as a third-generation DNA vaccine for AIDS prevention and immunotherapy.
Published Engineers achieve breakthrough in quantum sensing
(via sciencedaily.com) Original source A collaborative project has made a breakthrough in enhancing the speed and resolution of wide-field quantum sensing, leading to new opportunities in scientific research and practical applications.
Published Researchers are using RNA in a new approach to fight HIV
(via sciencedaily.com) Original source A pharmacy associate professor has developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy.
Published The cultural evolution of collective property rights
(via sciencedaily.com) Original source Common pool resources comprise around 65 percent of Earth's surface and vast tracts of the ocean. While examples of successful governance of these resources exist, the circumstances and mechanisms behind their development have remained unclear. Researchers have developed a simulation model to examine the emergence, stability and temporal dynamics of collective property rights.
Published Using metabolomics for assessing safety of chemicals may reduce the use of lab rats
(via sciencedaily.com) Original source Scientists have discovered a more robust way of grouping chemicals and using read-across for toxicological data to meet regulatory requirements, which could greatly reduce animal testing.
Published It's the spin that makes the difference
(via sciencedaily.com) Original source Biomolecules such as amino acids and sugars occur in two mirror-image forms -- in all living organisms, however, only one is ever found. Why this is the case is still unclear. Researchers have now found evidence that the interplay between electric and magnetic fields could be at the origin of this phenomenon.
Published New model identifies drugs that shouldn't be taken together
(via sciencedaily.com) Original source Researchers have developed a multipronged strategy to identify the transporters used by different drugs. Their approach, which makes use of both tissue models and machine-learning algorithms, has already revealed that a commonly prescribed antibiotic and a blood-thinner can interfere with each other.
Published Plastic recycling with a protein anchor
(via sciencedaily.com) Original source Polystyrene is a widespread plastic that is essentially not recyclable when mixed with other materials and is not biodegradable. A research team has now introduced a biohybrid catalyst that oxidizes polystyrene microparticles to facilitate their subsequent degradation. The catalyst consists of a specially constructed 'anchor peptide' that adheres to polystyrene surfaces and a cobalt complex that oxidizes polystyrene.
Published Unlocking the energetic secrets of collective animal movement: How group behavior reduces energy costs in fish
(via sciencedaily.com) Original source Researchers questioned if coordinated group movements by animals moving through a fluid could reduce the energy cost of locomotion. By combining biomechanics and bioenergetics the researchers found not only a significant amount of energy conservation, but also identified the reduced energy use per tail beat.
Published Even very low levels of pesticide exposure can affect fish for generations
(via sciencedaily.com) Original source Fish exposed to some pesticides at extremely low concentrations for a brief period of time can demonstrate lasting behavioral changes, with the impact extending to offspring that were never exposed firsthand, a recent study found.
Published Panama Canal expansion rewrites history of world's most ecologically diverse bats
(via sciencedaily.com) Original source In a new study, paleontologists describe the oldest-known leaf-nosed bat fossils, which were found along the banks of the Panama Canal. They're also the oldest bat fossils from Central America, preserved 20-million years ago when Panama and the rest of North America were separated from southern landmass by a seaway at least 120 miles wide.