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Categories: Biology: Biochemistry, Geoscience: Geography

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Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out their specific tasks and to form complex molecular machinery. However, our current understanding of such protein-protein interactions often lacks cellular contexts because they were usually studied in an in vitro system or in cells isolated from their tissue environment. Effective methods to investigate protein-protein interactions in a tissue-specific manner are largely missing.

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Water scarcity will intensify with climate and socioeconomic change, disproportionately impacting populations located in the Global South.

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Virtual Reality experiments have illuminated the rhythmic glue that could keep animals moving in synchrony.

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Primarily due to the impact of urbanisation and global warming, urban heatwaves have become a challenging issue worldwide, with Hong Kong persistently experiencing record-breaking high-temperature days. Mitigating urban heat through green and blue infrastructures is essential for creating a sustainable environment. Researchers have conducted a study on the effectiveness of green interventions in cooling urban heat across various regions that can assist policymakers in prioritizing effective interventions to develop sustainable cities.

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Treatment of autoimmune diseases like lupus has long relied on steroids to knock down the immune system, but more targeted therapies are currently undergoing clinical trials. To make sure these therapies get to the patients who will benefit, work is needed to identify the specific mutations behind each patient's disease. Researchers now report several dozen mutations associated with oversensitive toll-like receptors -- a major cause of autoimmune disease -- and linked two mutations to patients.

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Members of the vertebrate group including anglerfishes are unique in possessing a characteristic known as sexual parasitism, in which males temporarily attach or permanently fuse with females to mate. Now, researchers show that sexual parasitism arose during a time of major global warming and rapid transition for anglerfishes from the ocean floor to the deep, open sea.

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People who eat more ultra-processed foods like soft drinks, chips and cookies may have a higher risk of having memory and thinking problems and having a stroke than those who eat fewer processed foods, according to a new study. The study does not prove that eating ultra-processed foods causes memory and thinking problems and stroke. It only shows an association.

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A new study predicts future climate change impacts could disrupt the krill-heavy diet that humpback whales in the southern hemisphere consume.

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A study has discovered molecular pathways regulated by a gene traditionally used to control wheat-flowering behavior could be altered to achieve greater yields.

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Southern California's iconic sandy coastlines are vanishing at an alarming rate, and it's a warning sign for coastal communities worldwide, new research suggests.

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Populations of canola plants genetically engineered to be resistant to herbicides can survive outside of farms, but may be gradually losing their engineered genes, reports a new study.

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Animals and fungi predominantly use two different modes of cell division -- called open and closed mitosis, respectively. A new study has shown that different species of Ichthyosporea -- marine protists that are close relatives of both animals and fungi -- use either open and closed mitosis, closely correlated to whether the species has multinucleate life cycle stages. The study demonstrates the way animals do cell division might have evolved long before animals themselves did and how this is linked to an organism's life cycle.

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Researchers found that adding a newly developed modified sugar, BNAP-AEO, to gapmer antisense oligonucleotides (ASOs) increased their affinity for target RNAs, thus significantly enhancing their gene-silencing effects in vitro and in vivo. The BNAP-AEO modification also decreased gapmer ASO toxicity to the central nervous system (CNS), suggesting that it could improve the clinical application of ASO treatment of CNS disease.

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A new study demonstrates that kangaroos, wallabies and other Australian marsupials fear humans far more than any other predator.

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A new study shows that real-world ocean conditions make a huge difference in how viral infection affects host bacteria. The findings indicate it is very important to study cells and virocells under nutrient conditions that more closely resemble what they encounter in nature.

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Researchers trained an AI model to accurately predict male fruit flies' courtship behavior in response to any sight of a female. This breakthrough offers new insight into how the brain processes visual data and may someday pave the way for artificial vision technology.

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Extreme heat and extreme cold are both associated with increased risks of death from ischemic and hemorrhagic stroke, according to a new study. The researchers found that the link between extreme temperatures and stroke mortality was stronger in low-income countries than in high-income countries.

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Maize can grow successfully in very different local conditions. An international study has now demonstrated the important role of the plant root system. The researchers analyzed more than 9,000 varieties in the study and were able to show that their roots varied considerably -- depending on how dry the location is where each variety was cultivated. They were also able to identify an important gene that plays a role in the plant's ability to adapt. This gene could be the key to developing varieties of maize that cope better with climate change.

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A new study reveals that cows who are cuddled as therapy animals showed a strong preference for interactions with women when compared to men. In turn, the research, which opens a new era on whether some therapies may be initially stronger based upon gender and not procedure, highlighted that the women also reported greater attachment behaviors towards the steers.

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A substance naturally occurring in i.a. pomegranates, strawberries and walnuts can improve memory and treatment of Alzheimer's disease, a new study concludes.