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Categories: Biology: Biochemistry, Geoscience: Geology
Published Opportunities to improve future HIV vaccine candidates
(via sciencedaily.com) Original source An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study. The study findings draw comparisons between the immune system activity of past HIV vaccine study participants and people with HIV who naturally keep the virus from replicating even in the absence of antiretroviral therapy (ART). The latter individuals are often called 'long-term non-progressors' or 'elite controllers' (LTNPs/ECs).
Published Can you change a chicken into a frog, a fish or a chameleon?
(via sciencedaily.com) Original source Researchers have developed a theoretical framework that can reproduce and predict the patterns associated with gastrulation in a chicken embryo.
Published How the immune system fights to keep herpes at bay
(via sciencedaily.com) Original source In a study of lab-engineered cells, researchers identify how the immune system neutralizes the herpesvirus. The research maps, for the first time, the maneuvers used by virus and host in the cell nucleus, a poorly understood terrain of host-pathogen interaction. The findings could inform the design of new treatments for herpes and other viruses that replicate in the same way.
Published Gut bacteria of malnourished children benefit from key elements in therapeutic food
(via sciencedaily.com) Original source New research has identified key, naturally occurring biochemical components of a novel therapeutic food that is aimed at repairing malnourished children's underdeveloped gut microbiomes. The study also has identified the important bacterial strains that process these biochemical components. The findings may help guide treatment with a current food formulation and enable creation of new, more effective formulations in the future.
Published Enzymes can't tell artificial DNA from the real thing
(via sciencedaily.com) Original source Researchers have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab.
Published Earliest evidence for domestic yak found using both archaeology, ancient DNA
(via sciencedaily.com) Original source The high-altitude hero of the Himalayas, yak are among the few large animals that can survive the extremely cold, harsh and oxygen-poor conditions of the Tibetan Plateau. In the mountainous regions of Asia, yak and yak-cattle hybrids serve as vital sources of meat, milk, transportation and fuel. However, little is known about their history: when or where yak were domesticated. In a new study, researchers report archaeologically and genetically confirmed evidence for domestic yak, dating back 2,500 years, by far the oldest record.
Published Trees in wetter regions more sensitive to drought
(via sciencedaily.com) Original source This holiday season brings surprising news about your Christmas tree. Scientists just discovered that globally, trees growing in wetter regions are more sensitive to drought. That means if your tree hails from a more humid clime, it's likely been spoiled for generations.
Published Scientists unveil complete cell map of a whole mammalian brain
(via sciencedaily.com) Original source Researchers have created a complete cell atlas of a whole mammalian brain. This atlas serves as a map for the mouse brain, describing the type, location, and molecular information of more than 32 million cells and providing information on connectivity between these cells.
Published Wildfires also impact aquatic ecosystems
(via sciencedaily.com) Original source Researchers have shown that the effects of wildfires are not limited to terrestrial ecosystems. Aquatic ecosystems are also undergoing rapid changes. The study found that fire debris transforms lakes and other aquatic ecosystems, with implications for fisheries and water quality.
Published Nanoprobe with a barcode
(via sciencedaily.com) Original source Protein-splitting enzymes play an important role in many physiological processes. Such proteases are generally present in an inactive state, only becoming activated under certain conditions. Some are linked to diseases like infections or cancer, making it important to have methods that can selectively detect active proteases. Scientists have introduced a new class of protease-activity sensors: gold nanoparticles equipped with peptide DNA.
Published Cells move in groups differently than they do when alone
(via sciencedaily.com) Original source A protein that helps generate the force needed for single cells to move works differently in cells moving in groups, a new study shows.
Published How forests smell -- a risk for the climate?
(via sciencedaily.com) Original source Plants emit odors for a variety of reasons, such as to communicate with each other, to deter herbivores or to respond to changing environmental conditions. An interdisciplinary team of researchers carried out a study to investigate how biodiversity influences the emission of these substances. For the first time, they were able to show that species-rich forests emit less of these gases into the atmosphere than monocultures. It was previously assumed that species-rich forests release more emissions. The Leipzig team has now been able to disprove this assumption experimentally.
Published Study overturns conventional wisdom about wild turkey nesting survival
(via sciencedaily.com) Original source A new study finds that precipitation levels during nesting season are not related to reproductive success for wild turkeys, which runs counter to the conventional wisdom regarding the role that rainfall plays in wild turkey nesting success. The findings shed new light on how climate change may affect wild turkey populations.
Published Infection with stomach bacteria may increase risk of Alzheimer's disease
(via sciencedaily.com) Original source Infection with the stomach bacterium Helicobacter pylori could increase the risk of developing Alzheimer's disease: In people over the age of 50, the risk following a symptomatic infection can be an average of 11 percent higher, and even more about ten years after the infection, at 24 percent greater risk.
Published Mice possess natural gene therapy system
(via sciencedaily.com) Original source A previously mysterious small RNA molecule in mice is found to play a crucial role in gene expression, and may be the first identified member of a new class of regulatory RNAs.
Published What happens in the brain while daydreaming?
(via sciencedaily.com) Original source During quiet waking, brain activity in mice suggests the animals are daydreaming about a recent image. Having daydreams about a recently viewed image predicted how the brain would respond to the image in the future. The findings provide a clue that daydreams may play a role in brain plasticity.
Published Cell types in the eye have ancient evolutionary origins
(via sciencedaily.com) Original source In a comparative analysis across vertebrates of the many cell types in the retina -- mice alone have 130 types -- researchers concluded that most cell types have an ancient evolutionary history. Their remarkable conservation across species suggests that the retina of the last common ancestor of all mammals, which roamed the earth some 200 million year ago, must have had a complexity rivaling the retina of modern mammals.
Published A rare enzyme role change with bacterial defense system assembly
(via sciencedaily.com) Original source Scientists have revealed a never-before-seen phenomenon in a protein: Alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound to help bacteria commit suicide.
Published A sugar analysis could reveal different types of cancer
(via sciencedaily.com) Original source In the future, a little saliva may be enough to detect an incipient cancer. Researchers have developed an effective way to interpret the changes in sugar molecules that occur in cancer cells.
Published Best areas for rewilding European bison
(via sciencedaily.com) Original source Simulations integrate historical records, fossils, and ancient DNA to reveal why the European bison nearly went extinct, and pinpoint optimal areas for conservation. Since the near-extinction of the European bison, enormous conservation efforts have helped to restore wild populations, and its numbers are on the rise. However, the study authors argue that ensuring the species's long-term protection and recovery requires understanding why they nearly went extinct in the first place. 'Our study also suggests areas where rewilding attempts are most likely to be successful,' said lead author July Pilowsky, currently a disease ecologist at Cary Institute of Ecosystem Studies. Pilowsky completed the research while working on their PhD at University of Adelaide and University of Copenhagen.