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Categories: Biology: Biochemistry, Paleontology: General
Published Impact of 700 years of Inuvialuit subsistence hunting on beluga whales
(via sciencedaily.com) Original source An international team of researchers analyzed beluga whale bones retrieved from archaeological sites in the Mackenzie Delta, Northwest Territories, Canada, to shed light on the sustainability of centuries of Inuvialuit beluga whale subsistence harvests.
Published New mechanism of action kills cancer cells
(via sciencedaily.com) Original source Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in tumor cells. However, tumor cells have the ability to develop strategies to escape apoptosis, rendering the drugs ineffective. A research team now describes a new mechanism of action that kills cancer cells through ferroptosis.
Published A ketogenic diet could improve the response to pancreatic cancer therapy
(via sciencedaily.com) Original source Scientists have discovered a way to get rid of pancreatic cancer in mice by putting them on a high fat, or ketogenic, diet and giving them cancer therapy.
Published Decoding the world's largest animal genome
(via sciencedaily.com) Original source Scientists have sequenced the largest genome of all animals, the lungfish genome. Their data help to explain how the fish-ancestors of today's land vertebrates were able to conquer land.
Published Researchers call for genetically diverse models to drive innovation in drug discovery
(via sciencedaily.com) Original source Researchers unveiled an approach to drug discovery that could revolutionize how we understand and treat diseases. Their commentary explains the limitations of studies using traditional mouse models and proposes using genetically diverse mice and mouse and human cells to better predict human responses to drugs and diseases.
Published Newly discovered ability of comammox bacteria could help reduce nitrous oxide emissions in agriculture
(via sciencedaily.com) Original source An international research team has discovered that comammox bacteria, first identified by them in 2015, can grow using guanidine, a nitrogen-rich organic compound, as their sole energy and nitrogen source. This unique ability opens new avenues for targeted cultivation of these enigmatic microbes and could also provide a key to reducing agricultural nitrous oxide emissions.
Published Ecologists put an insect group on century-old map of biodiversity
(via sciencedaily.com) Original source The distribution of species around the globe is not a random process but an outcome resulting from several evolutionary mechanisms as well as past and current environmental limitations. As a result, since the mid-19th century, biologists have identified several main regions, called biogeographic realms, that depict these large ensembles of species around the world. These biogeographic realms represent one of the most fundamental descriptions of biodiversity on Earth and are commonly used in various fields of biology.
Published Giant fossil seeds from Borneo record ancient plant migration
(via sciencedaily.com) Original source Ancient fossil beans about the size of modern limes, and among the largest seeds in the fossil record, may provide new insight into the evolution of today's diverse Southeast Asian and Australian rainforests, according to researchers who identified the plants.
Published Exciting advance in stem cell therapy
(via sciencedaily.com) Original source A new technique for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential.
Published Pit-building venom mixers
(via sciencedaily.com) Original source Researchers show that the adaptation of antlions to their ecological niche has also changed their venom. They compared the venom system of antlion and closely related green lacewing larvae. Antlions produce a much more complex venom from three different venom glands than lacewing larvae do. All the venom proteins identified come from the insects themselves, not from symbiotic bacteria. Some of the toxins are new and appear to be unique to antlions. Waiting for their victims in pitfall traps in the sand, antlions can use their venom to immobilize larger prey. The venom therefore plays an important ecological role in adapting to their barren habitat.
Published Surprising insight into cancer comes from unique plant species that find different solutions to evolutionary challenges
(via sciencedaily.com) Original source A study has shown that different plant species tackle the same evolutionary hurdle in different ways, and the findings may give insight into aggressive forms of cancer.
Published Rewriting the evolutionary history of critical components of the nervous system
(via sciencedaily.com) Original source A new study has rewritten the conventionally understood evolutionary history of certain ion channels -- proteins critical for electrical signaling in the nervous system. The study shows that the Shaker family of ion channels were present in microscopic single cell organisms well before the common ancestor of all animals and thus before the origin of the nervous system.
Published Reduce, reuse, 're-fly-cle'
(via sciencedaily.com) Original source Black soldier flies are now commercially used to consume organic waste -- but genetic modifications proposed by bioscientists could see the insects digesting a wider variety of refuse, while also creating raw ingredients for industry.
Published Starvation and adhesion drive formation of keratinocyte patterns in skin
(via sciencedaily.com) Original source Cell-cell adhesion-induced patterning in keratinocytes can be explained by just starvation and strong adhesion researchers find.
Published Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease
(via sciencedaily.com) Original source Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease. Oleoyl-ACP-hydrolase (OLAH) is an enzyme involved in fatty acid metabolism. A study shows that OLAH drives severe disease outcomes.
Published Researchers ID body's 'quality control' regulator for protein folding
(via sciencedaily.com) Original source Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease. Fortunately, our bodies have a quality-control system that identifies misfolded proteins and marks them either for additional folding work or destruction, but how, exactly, this quality-control process functions is not entirely known. Researchers have now made a major leap forward in our understanding of how this quality-control system works by discovering the 'hot spot' where all the action takes place.
Published Why carbon nanotubes fluoresce when they bind to certain molecules
(via sciencedaily.com) Original source Nanotubes can serve as biosensors. They change their fluorescence when they bind to certain molecules. Until now, it was unclear why. Researchers have gained new insights into the cause of the fluorescence.
Published Bacteria in lakes fight climate change
(via sciencedaily.com) Original source Methane-oxidizing bacteria could play a greater role than previously thought in preventing the release of climate-damaging methane from lakes, researchers from Bremen report. They also show who is behind the process and how it works.
Published Low magnesium levels increase disease risk
(via sciencedaily.com) Original source A new study has identified why a diet rich in magnesium is so important for our health, reducing the risk of DNA damage and chronic degenerative disorders.
Published Mature forests vital in frontline fight against climate change
(via sciencedaily.com) Original source Mature forests have a key role to play in the fight against climate change -- extracting carbon dioxide (CO2) from the atmosphere and locking it into new wood.