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Categories: Biology: Biochemistry, Paleontology: Fossils
Published Nanocarrier with escape reflex
(via sciencedaily.com) Original source Protein-based drugs must be transported into cells in a way that prevents their immediate degradation. A new approach is intended to ensure that they remain intact only in certain cells, such as cancer cells. A Japanese research team has introduced a nanocarrier that can 'escape' from endosomes before its cargo is destroyed there. This ability to escape is only triggered within the endosomes of certain tumor cells.
Published Counting rays: Aerial surveys reveal ample populations in Southeast Florida
(via sciencedaily.com) Original source A unique long-term study quantified the abundance of whitespotted eagle and giant manta rays in Southeast Florida. Researchers conducted 120 survey flights between 2014 and 2021 from Miami north to the Jupiter Inlet. One or both species were seen on nearly every flight and both populations appear to be stable in the region. The giant manta rays were more abundant in the south and the whitespotted eagle rays were found all along the coast. Neither species seems to be deterred by the greater human population density in Fort Lauderdale/Miami.
Published Double trouble at chromosome ends
(via sciencedaily.com) Original source New findings suggest the end-replication problem, an old standby of biology textbooks, is twice as intricate as once thought.
Published Change in gene code may explain how human ancestors lost tails
(via sciencedaily.com) Original source A genetic change in our ancient ancestors may partly explain why humans don't have tails like monkeys.
Published Walleye struggle with changes to timing of spring thaw
(via sciencedaily.com) Original source Walleye are one of the most sought-after species in freshwater sportfishing, a delicacy on Midwestern menus and a critically important part of the culture of many Indigenous communities. They are also struggling to survive in the warming waters of the Midwestern United States and Canada. According to a new study, part of the problem is that walleye are creatures of habit, and the seasons -- especially winter -- are changing so fast that this iconic species of freshwater fish can't keep up.
Published New disease testing component facilitates lower-cost diagnostics
(via sciencedaily.com) Original source Biomedical researchers have developed a new, less expensive way to detect nuclease digestion -- one of the critical steps in many nucleic acid sensing applications, such as those used to identify COVID-19 and other infectious diseases.
Published First DNA study of ancient Eastern Arabians reveals malaria adaptation
(via sciencedaily.com) Original source People living in ancient Eastern Arabia appear to have developed resistance to malaria following the appearance of agriculture in the region around five thousand years ago.
Published Low-Temperature Plasma used to remove E. coli from hydroponically grown crops
(via sciencedaily.com) Original source In a new study, a team sterilized a hydroponic nutrient solution using low-temperature plasma generated from electricity and the oxygen in the atmosphere. This new sterilization technique may allow farmers to grow crops without the use of chemical pesticides, representing an important advance in agricultural technology for sustainable crop production.
Published New discovery shows how cells defend themselves during stressful situations
(via sciencedaily.com) Original source A recent study has unveiled an exciting discovery about how our cells defend themselves during stressful situations. The research shows that a tiny modification in the genetic material, called ac4C, acts as a crucial defender, helping cells create protective storage units known as stress granules. These stress granules safeguard important genetic instructions when the cell is facing challenges. The new findings could help shed light on relevant molecular pathways that could be targeted in disease.
Published Scientists use blue-green algae as a surrogate mother for 'meat-like' proteins
(via sciencedaily.com) Original source Researchers have not only succeeded in using blue-green algae as a surrogate mother for a new protein -- they have even coaxed the microalgae to produce 'meat fiber-like' protein strands. The achievement may be the key to sustainable foods that have both the 'right' texture and require minimal processing.
Published Microbial comics: RNA as a common language, presented in extracellular speech-bubbles
(via sciencedaily.com) Original source Decoding the conversations between microbes of hypersaline environments reveals deep insights into the origins of complex life.
Published 'Janitors' of the Sea: Overharvested sea cucumbers play crucial role in protecting coral
(via sciencedaily.com) Original source Researchers discovered that sea cucumbers -- sediment-eating organisms that function like autonomous vacuum cleaners of the ocean floor -- play an enormous role in protecting coral from disease.
Published Human stem cells coaxed to mimic the very early central nervous system
(via sciencedaily.com) Original source The first stem cell culture method that produces a full model of the early stages of the human central nervous system has been developed by a team of engineers and biologists.
Published Cutting-edge 'protein lawnmower' created
(via sciencedaily.com) Original source Scientists have designed the first synthetic protein-based motor which harnesses biological reactions to fuel and propel itself. 'Imagine if a Roomba could be powered only by the dirt it picks up,' says one of the authors of the study. The motor uses the digestive enzyme trypsin to cut the peptides and convert them into the energy it needs to propel itself.
Published Butterflies mimic each other's flight behavior to avoid predators
(via sciencedaily.com) Original source Researchers have shown that inedible species of butterfly that mimic each others' color patterns have also evolved similar flight behaviors to warn predators and avoid being eaten.
Published Scientists assemble a richer picture of the plight and resilience of the foothill yellow-legged frog
(via sciencedaily.com) Original source Up to only a few inches in length, with a lemon-hued belly, the foothill yellow-legged frog may seem unassuming. But its range once stretched from central Oregon to Baja California. In 2023, it was listed under the federal Endangered Species Act. Its rapidly decreasing range is due in part to a fungal pathogen called Batrachochytrium dendrobatidis, or Bd, that has devastated amphibians around the world.
Published Obesity disrupts normal liver function in mice
(via sciencedaily.com) Original source Your liver plays a vital role in your metabolism, the biological process which converts food into energy. We know that being overweight can negatively affect metabolic activity, but not exactly how. To better understand this, researchers compared the livers of mice which were a typical weight with mice which were obese. They were surprised to find that biological regulation of metabolic activity, after a period of feasting and fasting, was reversed between them. In typical mice, allosteric regulation (the process which controls metabolism) was inhibited during feeding and activated when fasting. However, in obese mice, allosteric regulation increased during feeding and decreased when fasting.
Published Predatory fish use rapid color changes to coordinate attacks
(via sciencedaily.com) Original source Striped marlin are some of the fastest animals on the planet and one of the ocean's top predators. When hunting in groups, individual marlin will take turns attacking schools of prey fish one at a time. Now a new study helps to explain how they might coordinate this turn-taking style of attack on their prey to avoid injuring each other. The key, according to the new work, is rapid color changes.
Published Blindness from some inherited eye diseases may be caused by gut bacteria
(via sciencedaily.com) Original source Sight loss in certain inherited eye diseases may be caused by gut bacteria, and is potentially treatable by antimicrobials, finds a new study in mice.
Published The small intestine adapt its size according to nutrient intake
(via sciencedaily.com) Original source Resizing of the intestine is a highly conserved strategy employed by a wide range of organisms to cope with fluctuation in nutrient availability. Nevertheless, very little is known about the mechanisms and signals underlying nutrient-mediated gut resizing. New research has identified one of the signaling pathways implicated in this process.