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Categories: Biology: Biochemistry, Paleontology: Fossils

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Researchers have created a new version of a microbe to compete economically with E. coli -- a bacteria commonly used as a research tool due to its ability to synthesize proteins -- to conduct low-cost and scalable synthetic biological experiments.

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A new clinical trial suggests that a combination of the drug vorinostat and immunotherapy can coax HIV-infected cells out of latency and attack them. The findings highlight how close -- yet still far -- researchers have come to developing a cure for HIV-1.

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Researchers have shed new light on how viral evolution, population immunity, and the co-circulation of other flu viruses shape seasonal flu epidemics.

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Sandalwood oil has been used worldwide for centuries. Now, a study is the first to demonstrate in vivo the chemo-preventive properties of a by-product of the oil in a mouse model. Results show administering alpha-santalol reduced visible prostate tumors, protected the normal tissue, and delayed progression from a precancerous condition to a high-grade form of cancer. These findings are significant because mortality in prostate cancer patients is mainly attributable to advanced stages of the disease.

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The capacity of intestinal stem cells to maintain cellular balance in the gut decreases upon aging. Researchers have discovered a new mechanism of action between the nutrient adaptation of intestinal stem cells and aging. The finding may make a difference when seeking ways to maintain the functional capacity of the aging gut.

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Fossils of a marine animal that lived 500 million years ago, combined with computer simulations, informed the design of a new soft robot.

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Charles Darwin -- arguably the most influential man of science in history, accumulated a vast personal library throughout his working life. Until now, 85 per cent of its contents were unknown or unpublished. This year, coinciding with Darwin's 215th birthday, The Complete Work of Charles Darwin Online, a scholarly project, has released an online 300-page catalogue detailing Darwin's complete personal library, with 7,400 titles across 13,000 volumes and items including books, pamphlets and journals.

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Scientists examined hundreds of birds in museum collections and discovered a suite of feather characteristics that all flying birds have in common. These 'rules' provide clues as to how the dinosaur ancestors of modern birds first evolved the ability to fly, and which dinosaurs were capable of flight.

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A new collaborative study analyzed fecal samples to shed light on how the fatal disease impacts the gut microbiome in deer, providing a promising tool for disease surveillance.

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Snail shells are often colorful and strikingly patterned. This is due to pigments that are produced in special cells of the snail and stored in the shell in varying concentrations. Fossil shells, on the other hand, are usually pale and inconspicuous because the pigments are very sensitive and have already decomposed. Residues of ancient color patterns are therefore very rare. This makes a new discovery all the more astonishing: researchers found pigments in twelve-million-year-old fossilized snail shells.

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Beaked whales are among the least studied mammals in the world. Now, a new study reveals surprising information about the Baird's beaked whale species.

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Nearly 400 exceptionally well-preserved fossils dating back 470 million years have been discovered in the south of France by two amateur paleontologists. The discovery provides unprecedented information on the polar ecosystems of the Ordovician period.

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Scientists have discovered that nighttime air pollution -- coming primarily form car exhaust and power plant emissions -- is responsible for a major drop in nighttime pollinator activity. Nitrate radicals (NO3) in the air degrade the scent chemicals released by a common wildflower, drastically reducing the scent-based cues that its chief pollinators rely on to locate the flower. The findings show how nighttime pollution creates a chain of chemical reactions that degrades scent cues, leaving flowers undetectable by smell. The researchers also determined that pollution likely has worldwide impacts on pollination.

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Researchers have discovered a previously unknown ability of a group of immune system cells, known as Atypical B cells (ABCs), to fight infectious diseases such as malaria. The scientists say ABCs could also be key to developing new treatments for chronic autoimmune conditions such as lupus.

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Researchers report the results of the first ever genome-wide association study (GWAS) of a biosafety level 4 (BSL-4) virus. The team found two key human genetic factors that could help explain why some people develop severe Lassa fever, and a set of LARGE1 variants linked to a reduced chance of getting Lassa fever. The work could lay the foundation for better treatments for Lassa fever and other similar diseases. The scientists are already working on a similar genetics study of Ebola susceptibility.

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Scientists have discovered a tiny worm species that infects and kills insects. These worms, called nematodes, could control crop pests in warm, humid places where other beneficial nematodes are currently unable to thrive.

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A newly discovered neural circuit mediates between navigational brain cells, acting as a sort of mental steering wheel.

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Researchers have shed new light on the ancient relationship between moss and fungi. They discovered that intricate moss-fungi interactions often depended on a third variable -- the presence of endobacteria within the fungi themselves.

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Tiny external structures in the wax coating of blueberries give them their blue color, researchers reveal.

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Researchers have made a groundbreaking discovery: a new cell that remembers allergies.