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Categories: Biology: Biochemistry, Paleontology: Fossils
Published Protein complex discovered to control DNA repair



The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team has now discovered a previously unrecognized control point for these processes. This could lead to a new approach for the development of cancer therapies aimed at inhibiting the repair of damaged cancer cells.
Published Prehistoric person with Turner syndrome identified from ancient DNA



Researchers have developed a new technique to measure the number of chromosomes in ancient genomes more precisely, using it to identify the first prehistoric person with mosaic Turner syndrome (characterized by one X chromosome instead of two [XX]), who lived about 2500 years ago.
Published Experiments in infant mice suggest new way to prevent spread of flu in people



Scientists have long known that some viruses and bacteria begin infections by latching first onto sugar molecules on the surfaces of cells lining the sinuses and throat of mammals, including humans. Viral particles, for instance, can attach to these molecules, called sialic acids, or SAs, like keys fitting into locks.
Published Toxic algae blooms: Study assesses potential health hazards to humans



Water samples from 20 sites were tested using a panel of immortalized human cell lines corresponding to the liver, kidney and brain to measure cytotoxicity. Results show that each control toxin induced a consistent pattern of cytotoxicity in the panel of human cell lines assayed. Known toxins were seen only during blooms. Because cell toxicity was seen in the absence of blooms, it suggests that there might be either emergent toxins or a combination of toxins present at those times. Findings suggest that other toxins with the potential to be harmful to human health may be present in the lagoon.
Published A new type of plant metalloreductase maintains root growth under low phosphorus



Phosphorus is essential for undisturbed plant growth and development. However, in many soils, phosphorus is only poorly available. One mechanism used by plants to increase phosphorus availability is the release of malate, an organic acid, which can form complexes with iron or aluminium in the soil, thereby liberating sorbed phosphate. However, this response can also result in iron overaccumulation, which can inhibit root growth.
Published New research sheds light on an old fossil solving an evolutionary mystery



Picrodontids -- an extinct family of placental mammals that lived several million years after the extinction of the dinosaurs -- are not primates as previously believed.
Published Red deer populations in Europe: More influenced by humans than by wolves and other predators



A new study shows that human hunting and land use have a decisive influence on red deer density in Europe. Red deer density is only reduced when wolves, lynx and bears co-occur at the same site.
Published Focus on biological processes does not capture the whole picture



The ocean plays a crucial role in the storage of carbon dioxide (CO2). The so-called marine biological carbon pump is an important research topic in this context. However a key component is often overlooked. Colleagues outline why it is insufficient to focus solely on biological processes when investigating the accumulation of CO2 in the ocean by the biological carbon pump.
Published Study on lamprey embryos sheds light on the evolutionary origin of vertebrate head



Scientists have investigated lamprey embryos using cutting-edge microscopic techniques to reveal interesting insights about vertebrate head evolution, clarifying an unresolved mystery in basic science.
Published 'Carbon vault' peat suffers greatly from drought



Peatlands are affected more by drought than expected. This is concerning, as these ecosystems are an important ally in the fight against climate change. Following long periods of drought, peat is able to absorb little to no extra carbon (CO2). Increasing biodiversity also does little to make peat more drought-resilient.
Published A beating biorobotic heart aims to better simulate valves



Combining a biological heart and a silicone robotic pump, researchers created a biorobotic heart that beats like a real one, with a focus on a valve on the left side of the heart. The heart valve simulator can mimic the structure, function, and motion of a healthy or diseased heart, allowing surgeons and researchers to demonstrate various interventions while collecting real-time data.
Published The extinction of the giant ape: Long-standing mystery solved



The largest ever primate Gigantopithecus blacki went extinct when other Asian great apes were thriving, and its demise has long been a mystery. A massive regional study of 22 caves in southern China explores a species on the brink of extinction between 295,000 and 215,000 years ago. As the environment became more seasonal, forest plant communities changed Primates such as orangutans adapted their eating habits and behaviors in response but G. blacki showed signs of stress, struggled to adapt and their numbers dwindled.
Published Scientists name the most common tropical tree species



Researchers have found almost identical patterns of tree diversity across the world's tropical forests. The study of over one million trees across 1,568 locations found that just 2.2% of tree species make up 50% of the total number of trees in tropical forests across Africa, the Amazon, and Southeast Asia. Each continent consists of the same proportion of a few common species and many rare species.
Published Largest diversity study of 'magic mushrooms' investigates the evolution of psychoactive psilocybin production



The genomic analysis of 52 Psilocybe specimens includes 39 species that have never been sequenced. Psilocybe arose much earlier than previously thought -- about 65 million years ago -- and the authors found that psilocybin was first synthesized in mushrooms in the genus Psilocybe. Their analysis revealed two distinct gene orders within the gene cluster that produces psilocybin. The two gene patterns correspond to an ancient split in the genus, suggesting two independent acquisitions of psilocybin in its evolutionary history. The study is the first to reveal such a strong evolutionary pattern within the gene sequences underpinning the psychoactive proteins synthesis.
Published Plant warfare: The crucial function of Nrc proteins in tomato defense mechanisms



New research delves into the intricate defense mechanisms of tomatoes against the notorious bacterial pathogen, Pseudomonas syringae pv. tomato (Pst). It's a classic tale of nature's arms race: as pathogens evolve to outsmart plant defenses, plants counter with more sophisticated immune responses.
Published With only the pawprints, researchers study elusive bobcat



With DNA recovered from animal tracks, scientists revealed information about the ancestry and microbial community of bobcats without having to sample the animal directly.
Published Smart skin bacteria are able to secrete and produce molecules to treat acne



An experimental study has shown that a type of skin bacterium can efficiently be engineered to produce a protein to regulate sebum production. This application could treat acne without compromising the homeostasis of the entire skin microbiome.
Published Large-scale mapping of pig genes could pave the way for new human medicines



Researchers have carried out complex genetic analyses of hundreds of pigs and humans to identify differences and similarities. This new knowledge can be used to ensure healthier pigs for farmers and can help the pharmaceutical industry breed better laboratory pigs for testing new medicines.
Published Nine new snail species discovered in Papua New Guinea, a biodiversity hot spot at risk



A new study describes nine new species of carnivorous land snails, all of which are so small they could fit together on a U.S. nickel. They present a rare opportunity to study a group that in many other places is disappearing fast. Worldwide, mollusks account for more than 50% of all recorded extinctions since the year 1500, and many of these were land snails from Pacific islands.
Published Life span increases in mice when specific brain cells are activated



A new study identifies, in mice, a critical communication pathway connecting the brain and the body's fat tissue in a feedback loop that appears central to energy production throughout the body. The research suggests that the gradual deterioration of this feedback loop contributes to the increasing health problems that are typical of natural aging.