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Categories: Biology: Biochemistry, Paleontology: Fossils

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Researchers have uncovered intriguing details about the origins and spread of the bottle gourd, one of the oldest domesticated crops. Their work unveils the genetic diversification and population history of this hard-shelled plant that was used to make bottles, instruments, and containers for over 10,000 years by ancient civilizations.

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Infectious diseases specialists call the medical field to be ready to deal with the impact of climate change on spreading diseases, such as malaria, Valley fever, E. coli and Lyme disease.

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A new study finds a complex interplay between diet, genes, and the gut microbiota that could explain why IBD develops.

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Motor neurons are the cells the brain uses to command muscles to act. Scientists typically thought of them as simple connections, much like the cables that link computers with their accessories. Now, in fly studies, researchers have discovered that single motor neurons can each direct an insect's body to move in far more complex ways than previously thought.

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Once thrown away, disposable diapers and sanitary pads can take hundreds of years to decompose, because they contain plastics and other synthetic polymers. But now, researchers are replacing these materials with components made from protein biomass that is often discarded. They are sustainable and biodegradable, and they could potentially allow future diapers and pads to be flushed down a toilet or used as fertilizer.

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Researchers have discovered that the mere act of attaching their microparticle 'backpacks' to neutrophils is enough to activate them against cancer -- no drugs needed. In experiments, backpack-bearing neutrophils shrank tumors and extended the survival of mice with cancer, and treated animals retained an immune memory of the disease. This approach opens the door to a new class of drug-free immunotherapy for cancer.

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In a series of trials involving trained distance runners, researchers found that ingesting a cranberry supplement for 28 consecutive days led to noticeable improvements in both performance and muscle fatigue following 1,500-metre time trials. Reoxygenation rates were faster and running speeds improved by 1.5 per cent. The researchers found that 28 days of cranberry extract consumption by elite level endurance runners demonstrated a trend toward increased speed in 1,500-metre time trials but not in 400-metre ones. However, they did notice that lactate buildup was reduced following the 400-metre but not the 1,500-metre compared to baseline. The data also indicated that the cranberry extract promoted better oxygen extraction by the muscle, improved lactate clearance and slower muscle deoxygenation.

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Human sweat contains a protein that may protect against Lyme disease. About one-third of the population carries a genetic variant of this protein that is associated with Lyme disease in genome-wide association studies.

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To better understand a carbon sink in danger, scientists are turning to tiny organisms that have long been overlooked.

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Dinosaurs get all the glory. But aetosaurs, a heavily armored cousin of modern crocodiles, ruled the world before dinosaurs did. These tanks of the Triassic came in a variety of shapes and sizes before going extinct around 200 million years ago. Today, their fossils are found on every continent except Antarctica and Australia.

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Some soil bacteria can acquire sets of genes that enable them to pump the heavy metal nickel out of their systems, a study has found. This enables the bacteria to not only thrive in otherwise toxic soils but help plants grow there as well. A research team pinpointed a set of genes in wild soil bacteria that allows them to do this in serpentine soils which have naturally high concentrations of toxic nickel. The genetic discovery could help inform future bioremediation efforts that seek to return plants to polluted soils.

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Heparin, the world's most widely used blood thinner, is used during procedures ranging from kidney dialysis to open heart surgery. Currently, heparin is derived from pig intestines, but scientists have discovered how to make it in the lab. They have also developed a path to a biomanufacturing process that could potentially revolutionize how the world gets its supply of this crucial medicine.

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Researchers have used a series of artificial stream channels to mimic the behavior of headwater creeks under future climate change scenarios. They found that drier conditions shifted the life cycles of the algae and insects that form the base of the alpine food web. However, because species adjusted to the shifts in a variety of ways, the stream ecosystems were generally resilient to the changing conditions.

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Researchers have developed a strategy for using genomics to monitor for and identify emerging resistance to pesticides, helping farmers prolong the effectiveness of pest management tools.

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Our eating habits in industrialized societies are far removed from those of ancient humans. This is impacting our intestinal flora, it seems, as newly discovered cellulose degrading bacteria are being lost from the human gut microbiome, especially in industrial societies.

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Polyphenols, abundant in fruits, vegetables, tea, and coffee, offer potential health benefits. However, owing to low bioavailability, the mechanisms underlying their beneficial effects remain unknown. In a recent study, researchers have explored the interaction between polyphenols and human sensory receptors. Their findings elucidate how polyphenols influence brain function and metabolic pathways by interacting with gut receptors, explaining their role in well-being and nutrition innovation.

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The development of hair was of central importance for the evolution of mammals and thus also of humans. However, the evolutionary origin of the genetic program of hair was previously unknown. Researchers have now been able to show that important hair components and their genetic control have already evolved in amphibians. Human hair therefore shows unexpected similarities to the claws of clawed frogs.

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Scientists have discovered how female Diadem butterflies have evolved to look like African Queen butterflies to repel predators.

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Research is exploring how to add value to lignin by breaking it down into small molecules that are structurally similar to oxygenated hydrocarbons. These renewable chemicals are key components in many industrial processes and products, but they are traditionally sourced from non-renewable petroleum.

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The curvature of a surface determines the migration behavior of biological cells. They preferentially move along valleys or grooves while avoiding ridges. These findings gave rise to a model predicting cellular behavior. Such universal principles now allow a better understanding of the migration of immune and cancer cells, paving the way for new treatment options.